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CAS No 300-37-8 , 3,5-DIIODO-4-OXO-1(4H)PYRIDINEACETIC ACID-2,2&prime

  • Name: 3,5-DIIODO-4-OXO-1(4H)PYRIDINEACETIC ACID-2,2&prime
  • Synonyms: bis(2-hydroxyethyl)ammonium 1,4-dihydro-3,5-diiodo-4-oxo-1-pyridylacetate;diodone;-IMINODIETHANOL SALT ;3,5-DIIODO-4-OXO-1(4H)PYRIDINEACETIC ACID-2,2′
  • CAS Registry Number:
  • Flash Point: 209.5°C
  • Boiling Point: 422.8°Cat760mmHg
  • Density: g/cm3
  • Safety Statements: Moderately toxic by intravenous route. When heated to decomposition it emits very toxic fumes of NOx and I−.
  • Flash Point: 209.5°C
  • EINECS: 206-089-4
  • Molecular Weight: 510.09
  • InChI: InChI=1/C7H5I2NO3.C4H11NO2/c8-4-1-10(3-6(11)12)2-5(9)7(4)13;6-3-1-5-2-4-7/h1-2H,3H2,(H,11,12);5-7H,1-4H2
  • Molecular Formula: C7H5I2O3•C4H11NO2
  • Molecular Structure:CAS No:300-37-8 3,5-DIIODO-4-OXO-1(4H)PYRIDINEACETIC ACID-2,2&prime

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References of 3,5-DIIODO-4-OXO-1(4H)PYRIDINEACETIC ACID-2,2&prime
Title: Iodopyracet
CAS Registry Number: 300-37-8
CAS Name: 3,5-Diiodo-4-oxo-1(4H)-pyridineacetic acid compound with 2,2￠-iminobis[ethanol] (1:1)
Synonyms: bis(hydroxyethyl)ammonium 3,5-diiodo-4-pyridone-N-acetate; diethanolamine 3,5-diiodo-4-pyridone-N-acetate; 3,5-diiodo-4-pyridone-N-acetic acid diethanolamine salt; diodone
Manufacturers' Codes: RP-3203
Trademarks: Diatrast; Diodrast (Winthrop); Iopyracil; Nosylan; Neo-Methiodal; Neo-Skiodan; Neo-Tenebryl; Nosydrast; Oparenol; Per-Abrodil; Per-Radiographol; Pyelosil; Pylumbrin; Savac (Am. Cyanamid); Umbradil; Uriodone; Vasiodone; Xumbradil (Astra Pharm.)
Molecular Formula: C11H16I2N2O5
Molecular Weight: 510.06
Percent Composition: C 25.90%, H 3.16%, I 49.76%, N 5.49%, O 15.68%
Literature References: Prepn: FR 728634 (1931 to I. G. Farbenhind AG); J. Reitmann, US 1993039 (1935 to Winthrop). Pharmacology, toxicology and radiographic studies: R. St. A. Heathcote, R. A. Gardner, Br. J. Radiol. 6, 304 (1933). HPLC determn in biological fluids: P. Hekman, C. A. M. Van Ginneken, J. Chromatogr. 182, 492 (1980).
Properties: Odorless powder, dec 155-157°. Soly: about 36% in water; about 12% in methanol, much less sol in ice-cold methanol. Practically insol in acetone, ether, chloroform. pH of aq solns: 5 to 8, depending on concn. 3,5-Diiodo-4-pyridone-N-acetic acid separated by pptn with dil HCl and dried at 100°, mp 245-249°, and contains not less than 61.5% and not more than 63.5% iodine: N.F. XI.
Melting point: mp 245-249°
 
Derivative Type: Iodopyracet Injection
Properties: 35% (w/v) soln of the diethanolamine salt of 3,5-diiodo-4-pyridone-N-acetic acid. Contains about 22% I (w/v). d425 1.185. Neutral to litmus.
Density: d425 1.185
 
Derivative Type: Iodopyracet Concentrated Solution
Trademarks: Diodrast Concentrated Solution (Winthrop)
Properties: 70% soln (w/v) of the diethanolamine salt of 3,5-diiodo-4-pyridone-N-acetic acid. Contains about 44% I (w/v). Neutral to litmus.
 
Derivative Type: Iodopyracet Compound Solution
Trademarks: Diodrast Compound Solution (Winthrop)
Properties: Soln contg approx 40.5% (w/v) of the diethanolamine salt and approx 9.5% (w/v) of the diethylamine salt of 3,5-diiodo-4-pyridone-N-acetic acid. Contains about 25% I. Neutral to litmus. d425 1.270.
Density: d425 1.270
 
Therap-Cat: Diagnostic aid (radiopaque medium?urographic).
Therap-Cat-Vet: Diagnostic aid (radiopaque medium).
Keywords: Diagnostic Aid (Radiopaque Medium).