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CAS No 29216-28-2 , 10-(1-azabicyclo[2.2.2]octan-3-ylmethyl)phenothiazine

  • Name: 10-(1-azabicyclo[2.2.2]octan-3-ylmethyl)phenothiazine
  • Synonyms: Butix; Virginan; Vigigan; Instotal; Metaplexan; Mircol; Mequitazinum [INN-Latin]; Mequitazina [Spanish];Primalan;10-(1-azabicyclo[2.2.2]octan-3-ylmethyl)phenothiazine;
  • CAS Registry Number:
  • Density: 1.28 g/cm3
  • Safety Statements: Poison by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. An antihistamine. When heated to decomposition it emits toxic fumes of SOx and NOx.
  • EINECS: 249-521-7
  • Molecular Weight: 322.46708
  • InchiKey: HOKDBMAJZXIPGC-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H22N2S/c1-3-7-19-17(5-1)22(18-6-2-4-8-20(18)23-19)14-16-13-
    21-11-9-15(16)10-12-21/h1-8,15-16H,9-14H2
  • Molecular Formula: C20H22N2S
  • Molecular Structure:CAS No:29216-28-2 10-(1-azabicyclo[2.2.2]octan-3-ylmethyl)phenothiazine

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29216-28-2 MEQUITAZINE

  • CAS: 29216-28-2 MF: C20H22N2S MW: 322.47 EINECS: 249-521-7 mp 143-145°C storage temp. Refrigerator Chemical Properties White Solid Usage It is an antihistamine Purity: 99% Usage: API Package: 1KG foil bag; 25Kg drum
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References of 10-(1-azabicyclo[2.2.2]octan-3-ylmethyl)phenothiazine
Title: Mequitazine
CAS Registry Number: 29216-28-2
CAS Name: 10-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-10H-phenothiazine
Synonyms: 10-(3-quinuclidinylmethyl)phenothiazine
Manufacturers' Codes: LM-209
Trademarks: Butix (Fabre); Metaplexan (Rh>e-Poulenc); Mircol (Rh>e-Poulenc); Primalan (Inava); Zesulan (Toyo Jozo)
Molecular Formula: C20H22N2S
Molecular Weight: 322.47
Percent Composition: C 74.49%, H 6.88%, N 8.69%, S 9.94%
Literature References: Prepn: G. Gueremy et al., DE 2009555 corresp to US 3987042 (1970, 1976 to Sogeras). Absorption, distribution, and excretion: A. Uzan et al., Xenobiotica 6, 633 (1976). Biotransformation: eidem, ibid. 649. Pharmacologic study: eidem, J. Pharm. Pharmacol. 31, 701 (1979). Clinical studies: J. Blamoutier, Curr. Med. Res. Opin. 5, 366 (1978); P. Laugier, M. Orusco, ibid. 371.
Properties: Crystals from acetonitrile, mp 130-131°.
Melting point: mp 130-131°
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Tricyclics; Phenothiazines.