Home > Name List By other > [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 4-[4-...

CAS No 29069-24-7 , [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate

  • Name: [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate
  • Synonyms: [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate;
  • CAS Registry Number:
  • Melting Point: 646.641
  • Flash Point: 432.5°C
  • Boiling Point: 791.5°C at 760 mmHg
  • Density: 1.3g/cm3
  • Refractive index: 1.606
  • Flash Point: 432.5°C
  • EINECS: 249-410-3
  • Molecular Weight: 646.6409
  • InchiKey: HFVNWDWLWUCIHC-GUPDPFMOSA-N
  • InChI: InChI=1S/C35H45Cl2NO6/c1-33-14-12-26(39)20-24(33)8-11-27-28-13-15-35(43,34(28,2)21-29(40)32(27)33)30(41)22-44-31(42)5-3-4-23-6-9-25(10-7-23)38(18-16-36)19-17-37/h6-7,9-10,12,14,20,27-29,32,40,43H,3-5,8,11,13,15-19,21-22H2,1-2H3/t27-,28-,29-,32+,33-,34-,35-/m0/s1
  • Molecular Formula: C35H45Cl2NO6
  • Molecular Structure:CAS No:29069-24-7 [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate

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29069-24-7 Prednimustine

  • United States LGM Pharma [Manufacturer]
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  • Address: 922 Clint Moore Road
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29069-24-7 Prednimustine

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29069-24-7 [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate

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29069-24-7 PREDNIMUSTINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
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References of [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate
Title: Prednimustine
CAS Registry Number: 29069-24-7
CAS Name: (11b)-21-[4-[4-[Bis(2-chloroethyl)amino]phenyl]-1-oxobutoxy]-11,17-dihydroxypregna-1,4-diene-3,20-dione
Synonyms: 11b,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-[4-[p-[bis(2-chloroethyl)amino]phenyl]butyrate]; prednisolone 21-[4-[p-[bis(2-chloroethyl)amino]phenyl]butyrate]
Manufacturers' Codes: Leo-1031
Trademarks: Sterecyt (Pharmaleo); Stereocyt (Bellon)
Molecular Formula: C35H45Cl2NO6
Molecular Weight: 646.64
Percent Composition: C 65.01%, H 7.01%, Cl 10.97%, N 2.17%, O 14.85%
Literature References: Prednisolone ester of chlorambucil, q.v. Prepn: H. F. Fex et al., DE 2001305 corresp to US 3732260 (1970, 1973 both to AB Leo). In vitro study: A. H. Evenaar et al., Eur. J. Cancer 9, 773 (1973). Metabolism: R. Y. Kirdani et al., Oncology 35, 47 (1978). Clinical studies: L. Hakarsson et al., ibid. 103; J. E. Johnsson et al., Cancer Treat. Rep. 63, 421 (1970). Toxicity and antitumor activity study: K. R. Harrap et al., Eur. J. Cancer 13, 873 (1977). Series of articles on pharmacology, toxicology and clinical efficacy: Semin. Oncol. 13, Suppl. 1, 1-44 (1986).
Properties: Crystals from methanol-water, mp 163-164°. [a]D24 +92.9° (c = 1.06 in chloroform).
Melting point: mp 163-164°
Optical Rotation: [a]D24 +92.9° (c = 1.06 in chloroform)
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Alkylating Agents; Nitrogen Mustards.