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CAS No 274901-16-5 , Vildagliptin

  • Name: Vildagliptin
  • Synonyms: (-)-(2S)-1-[[(3-Hydroxytricyclo[3.3.1.1[3,7]]dec-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile;Vildagliptin;
  • CAS Registry Number:
  • Melting Point: 153-155?C
  • Density: 1.27 g/cm3
  • Molecular Weight: 303.40
  • InChI: InChI=1/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m1/s1
  • Molecular Formula: C17H25N3O2
  • Molecular Structure:CAS No:274901-16-5 Vildagliptin

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274901-16-5 Vildagliptin

  • Product Name: Vildagliptin CAS No.:274901-16-5 Appearance: White or off-white crystalline powder Purity:>99%
  • China Nanjing CHICO Pharmaceutial Co.,LTD. [Manufacturer]
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274901-16-5 Vildagliptin

  • Vildagliptin (previously identified as LAF237, trade names Zomelis, Galvus, cas 274901-16-5) is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin (cas 274901-16-5) i...
  • China Viwit [Manufacturer]
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274901-16-5 Vildagliptin

  • Product Name: Vildagliptin (NVP-LAF 237);(-)-(2S)-1-[[(3-Hydroxytricyclo[3.3.1.1[3,7]]dec-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile;Vildagliptin;(-)-(2S)-1-[[(3-Hydroxytricyclo[3.3.1.1[3,7]]dec-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile;2-Pyrrol...
  • China Shanghai Send Pharmaceutical Technology Co., Ltd [Manufacturer]
  • Tel: 86-21-50266790
  • Fax: 86-21-50266790
  • Address: No.300 Chuantu Road Pudong District Shanghai,China Shanghai,ShanghaiChina
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274901-16-5 Vildagliptin

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China null,ZheJiangChina
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274901-16-5 Vildagliptin

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
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274901-16-5 Vildagliptin

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
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  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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274901-16-5 Vildagliptin

  • China Xilin Chemical Group Co., Ltd null
  • Tel: +86-(0)-15527136576
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  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, null,nullChina
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274901-16-5 VILDAGLIPTIN

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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274901-16-5 VILDAGLIPTIN

  • France DIVERCHIM SA [Manufacturer]
  • Tel: +33 (0) 3 44 64 61 90
  • Fax: +33 (0) 3 44 64 61 99
  • Address: DIVERCHIM SA
    "Les marches de l'Oise"
    100, rue Louis Blanc
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274901-16-5 Vildagliptin

  • China TaiZhou HiKong Chemical Co., Ltd. null
  • Tel: +86-18967213045,13957694715
  • Fax: +86-(580)-6033180,6034626
  • Address: Taizhou Economic Technical Development Zone, Taizhou, Zhejiang 318000, null,nullChina
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References of Vildagliptin
Title: Vildagliptin
CAS Registry Number: 274901-16-5
CAS Name: (2S)-1-[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile
Synonyms: 1-[[(3-hydroxy-1-adamantyl) amino]acetyl]-2-cyano-(S)-pyrrolidine
Manufacturers' Codes: LAF-237; NVP-LAF237
Trademarks: Galvus (Novartis)
Molecular Formula: C17H25N3O2
Molecular Weight: 303.40
Percent Composition: C 67.30%, H 8.31%, N 13.85%, O 10.55%
Literature References: Dipeptidyl peptidase-IV (DPP-IV) inhibitor. Prepn: E. Villhauer, WO 0034241; idem, US 6166063 (both 2000 to Novartis); and pharmacology: idem et al., J. Med. Chem. 46, 2774 (2003). Clinical evaluation in type 2 diabetes: B. Ahrén et al., J. Clin. Endocrinol. Metab. 89, 2078 (2004); in combination with metformin: idem et al., Diabetes Care 27, 2874 (2004). Review of development and therapeutic potential: D. Barlocco, Curr. Opin. Invest. Drugs 5, 1094-1100 (2004).
Properties: White solid from ethyl acetate, mp 138-140°; from 2-propanol, mp 148-150°. [a] -78.3° (c = 9.73 in methanol).
Melting point: mp 138-140°; mp 148-150°
Optical Rotation: [a] -78.3° (c = 9.73 in methanol)
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic; Dipeptidyl Peptidase IV Inhibitors .