Home > Name List By 4 > 4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine

CAS No 27314-97-2 , 4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine

  • Name: 4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine
  • Synonyms: 3-Amino-1,2,4-benzotriazine-1,4-dioxide; WIN 59075; SR 4233;Tirazone; Win-59075;4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine; 27314-97-2; SR-4233;
  • CAS Registry Number:
  • Density: 1.68 g/cm3
  • Refractive index: 1.777
  • Safety Statements: 26-36
  • Hazard Symbols: Xi: Irritant;
  • Molecular Weight: 178.14814
  • InchiKey: QVMPZNRFXAKISM-UHFFFAOYSA-N
  • InChI: InChI=1S/C7H6N4O2/c8-7-9-11(13)6-4-2-1-3-5(6)10(7)12/h1-4,8,12H
  • Risk Statements: 36/37/38
  • Molecular Formula: C7H6N4O2
  • Molecular Structure:CAS No:27314-97-2 4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine

Related products

Search by region :

Select to

27314-97-2 3-amino-1,2,4-benzotriazine-1,4-dioxide

Contact Supplier

27314-97-2 3-amino-1,2,4-benzotriazine-1,4-dioxide

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
Contact Supplier

27314-97-2 Tirapazamine

  • Tirapazamine B83649 27314-97-2
  • China bepharm ltd. null
  • Tel: 86-21-51816456
  • Address: 128 Xiangyin Road, Room C320-321 Yangpu District, Shanghai 200433, China null,nullChina
Contact Supplier

27314-97-2 Tirapazamine

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
Contact Supplier

27314-97-2 Tirapazamine

  • Tirapazamine 27314-97-2 Tretinoin 302-79-4 Vandetanib 443913-73-3 Varenicline tartrate 375815-87-5 Valsartan 137862-53-4 Verapamil HCl 36622-28-3 Vinflunine Tartrate 162652-95-1 Vinorelbine (BICINS ) 56124-62-0 vinorelbine tartrate 125317-39-7 Vildag...
  • China Wuhan Sunrise Technology development company limited [Manufacturers]
  • Tel: +86-27-83314682
  • Fax: 86 27 83314682
  • Address: Floor 5, Wunan Road No.15, Haixia Investment Zone, Wujiashan Wuhan, China Wuhan,HubeiChina
Contact Supplier

27314-97-2 3-amino-1,2,4-benzotriazine-1,4-dioxide

  • Hong kong ADVANCED TECH. & IND. CO., LTD. [Distributor/Wholesaler]
  • Tel: 86-23902293
  • Fax: 86-27898314
  • Address: UNIT B, 1/F, CHEONG SHING IND. BLDG., 17 WALNUT ST., TAI KOK TSUI, KLN, HONG KONG Hong Kong,nilHong kong
Contact Supplier

27314-97-2 Tirapazamine

  • China Hangzhou Pharma & Chem Co.,Ltd. [Manufacturers]
  • Tel: +86-571-87040515
  • Fax: +86-571-87214761
  • Address: Rm.1201,QinglianBldg.No,139QingchunRd,HangzhouCity,Zhejiang,China Hangzhou,ZhejiangChina
Contact Supplier

27314-97-2 Tirapazamine

  • China Kangrui BIO-TECH Co.,Ltd.(H.K.) [Manufacturers]
  • Tel: 0086-571-86680744
  • Fax: 0086-571-86680744
  • Address: 3-704, Xixi Fengshang, Wensan West Road, Hangzhou, Zhejiang, China Hangzhou,ZhejiangChina
Contact Supplier

27314-97-2 TIRAPAZAMINE

  • China Hangzhou Pharma & Chem Co., Ltd. [Manufacturer]
  • Tel: +86 571 87040515
  • Fax: +86 571 87214761
  • Address: Hangzhou Pharma & Chem Co., Ltd.
    139 Qingchun Road, Hangzhou City,
    Zhejiang, China 310003 null,nullChina
Contact Supplier

27314-97-2 3-amino-1,2,4-benzotriazine-1,4-dioxide

  • China Wuhan LR Chemical Co.,Ltd [Manufacturer, Distributor/Wholesaler]
  • Tel: 86-027-15926275869
  • Fax: 86-027-87674578
  • Address: Guangguguoji, East Lake Hi-Tech Development Zone wuhan,hubeiChina
Contact Supplier

Select to

1/1
References of 4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine
Title: Tirapazamine
CAS Registry Number: 27314-97-2
CAS Name: 1,2,4-Benzotriazin-3-amine 1,4-dioxide
Synonyms: 3-amino-1,2,4-benzotriazine 1,4-dioxide
Manufacturers' Codes: NSC-130181; SR-4233; Win-59075
Trademarks: Tirazone (Sanofi Winthrop)
Molecular Formula: C7H6N4O2
Molecular Weight: 178.15
Percent Composition: C 47.19%, H 3.39%, N 31.45%, O 17.96%
Literature References: Bioreductive anticancer agent; selectively toxic to cells under hypoxic conditions. Prepn: R. F. Robbins, K. Schofield, J. Chem. Soc. 1957, 3186; J. C. Mason, G. Tennant, J. Chem. Soc. B 1970, 911. See also: K. Ley et al., DE 2204574; eidem, US 3868371 (1973, 1975 both to Bayer). HPLC determn in plasma: H. Robin, Jr. et al., Cancer Chemother. Pharmacol. 36, 266 (1995). Review of pharmacology and mechanism of action studies: J. M. Brown, Br. J. Cancer 67, 1163-1170 (1993). Clinical evaluation in combination with cisplatin: C. A. Johnson et al., J. Clin. Oncol. 15, 773 (1997).
Properties: Orange needles from methanol, mp 229-230° (dec) (Robbins, Scholfield). Also reported as reddish-golden crystals from water + acetic acid, mp 220° (dec) (Ley). uv max: 272, 474 nm (log e 4.24, 3.52).
Melting point: mp 229-230° (dec) (Robbins, Scholfield); mp 220° (dec) (Ley)
Absorption maximum: uv max: 272, 474 nm (log e 4.24, 3.52)
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic.