CAS No 25155-18-4 , benzyl-dimethyl-[2-[2-[2-methyl-4-(2,4,
4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]azanium

Title: Methylbenzethonium Chloride
CAS Registry Number: 25155-18-4
CAS Name: N,N-Dimethyl-N-[2-[2-[methyl-4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethyl]benzenemethanaminium chloride
Synonyms: benzyldimethyl[2-[2-(p-1,1,3,3-tetramethylbutylcresoxy)ethoxy]ethyl]ammonium chloride; [2-[2-(p-octylcresoxy)ethoxy]ethyl]dimethylbenzylammonium chloride; benzyldimethyl[2-[2-[4-(1,1,3,3-tetramethylbutyl)tolyloxy]ethoxy]ethyl]ammonium chloride
Molecular Formula: C28H44ClNO2
Molecular Weight: 462.11
Percent Composition: C 72.77%, H 9.60%, Cl 7.67%, N 3.03%, O 6.92%
Literature References: Quaternary ammonium salt with antimicrobial activity. Germicidal activity: F. Hart, C. L. Huyck, J. Am. Pharm. Assoc. Sci. Ed. 37, 272 (1948). In vitro activity vs Leishmania major: J. El-On, G. Messer, Am. J. Trop. Med. Hyg. 35, 1110 (1986). Clinical trial in combination with paramomycin, q.v., in cutaneous leishmaniasis: G. Krause, A. Kroeger, Trans. R. Soc. Trop. Med. Hyg. 88, 92 (1994). Review of properties, commercial uses and toxicology: J. Am. Coll. Toxicol. 4, 65-106 (1985).
 
Derivative Type: Monohydrate
CAS Registry Number: 1320-44-1
Trademarks: Diaparene (Sterling Winthrop); Hyamine 10X (Rohm & Haas)
Properties: Bitter tasting crystals, mp 161-163°. Freely sol in water, alcohol, cellosolve, chloroform, hot benzene. LD50 in rats (mg/kg): 100 s.c. (Hart, Huyck).
Melting point: mp 161-163°
Toxicity data: LD50 in rats (mg/kg): 100 s.c. (Hart, Huyck)
 
Use: In cosmetics as preservative; cationic surfactant.
Therap-Cat: Antiseptic, disinfectant.
Keywords: Antiseptic/Disinfectant; Quaternary Ammonium Compounds.