Title: Dicapthon
CAS Registry Number: 2463-84-5
CAS Name: Phosphorothioic acid
O-(2-chloro-4-nitrophenyl)
O,O-dimethyl ester
Synonyms: O,O-dimethyl
O-(2-chloro-4-nitrophenyl)phosphorothioate;
O,O-dimethyl-
O-(2-chloro-4-nitrophenyl)thionophosphate;
p-nitro-
o-chlorophenyl dimethyl thionophosphate; isochlorothion
Manufacturers' Codes: American Cyanamid 4124; insecticide ACC 4124
Trademarks: Dicaptan
Molecular Formula: C8H9ClNO5PS
Molecular Weight: 297.65
Percent Composition: C 32.28%, H 3.05%, Cl 11.91%, N 4.71%, O 26.88%, P 10.41%, S 10.77%
Literature References: Prepn: J. H. Fletcher,
US 2664437; Geoghegan, McPherson,
US 2784207 (1953, 1957 both to Am. Cyanamid); Schrader,
Angew. Chem. 66, 265 (1954);
idem, Die Entwicklung neuer insektizider Phosphors?ure-Ester (Verlag Chemie, 3rd ed., 1963) pp 289-291. Toxicity study: T. B. Gaines,
Toxicol. Appl. Pharmacol. 14, 515 (1969).
Properties: Crystals from methanol, mp 53°. Sol in acetone, cyclohexanone, ethyl acetate, toluene, xylene, ethylene glycol, propylene glycol, some oils. Practically insol in water. LD50 in male, female rats (mg/kg): 400, 330 orally; 790, 1250 dermally (Gaines).
Melting point: mp 53°
Toxicity data: LD50 in male, female rats (mg/kg): 400, 330 orally; 790, 1250 dermally (Gaines)
CAUTION: Cholinesterase inhibitor.
Use: Insecticide.
Status: This monograph has been retired and is no longer subject to revision or update.