Home > Name List By a > Apamin

CAS No 24345-16-2 , Apamin

  • Name: Apamin
  • Synonyms: 66: PN: WO2008088422 FIGURE: 8 claimed protein; Apamin (reduced), cyclic (1® 68: PN:WO2006116156 SEQID: 68 claimed protein; Apamine;Apamin;15)-bis(disulfide);11),(3®32,15-(Iminoethaniminopropanodithiomethano)-31H-pyrrolo[2,1-e1][1,2,5,8,11,14,17,20,23,26,29,32,35,38]dithiadodecaazacyclohentetracontine,cyclic peptide deriv.; L-Histidinamide,L-cysteinyl-L-asparaginyl-L-cysteinyl-L-lysyl-L-alanyl-L-prolyl-L-a-glutamyl-L-threonyl-L-alanyl-L-leucyl-L-cysteinyl-L-alanyl-L-arginyl-L-arginyl-L-cysteinyl-L-glutaminyl-L-glutaminyl-,cyclic (1® Ro 23-6721;
  • CAS Registry Number:
  • Transport: 2811
  • Refractive index: 1.724
  • Safety Statements: Poison by intravenous, parenteral, intracerebral, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of SOx and NOx.
  • EINECS: 246-182-7
  • Molecular Weight: 2027.65
  • InChI: InChI=1/C79H131N31O24S4/c1-35(2)26-49-70(127)107-51-31-136-135-30-41(81)63(120)105-50(28-57(84)114)71(128)108-53(73(130)99-42(12-7-8-22-80)64(121)96-38(5)77(134)110-25-11-15-54(110)75(132)102-47(18-21-58(115)116)69(126)109-59(39(6)111)76(133)95-37(4)62(119)104-49)33-138-137-32-52(106-66(123)44(14-10-24-92-79(88)89)98-65(122)43(13-9-23-91-78(86)87)97-61(118)36(3)94-72(51)129)74(131)101-45(16-19-55(82)112)67(124)100-46(17-20-56(83)113)68(125)103-48(60(85)117)27-40-29-90-34-93-40/h29,34-39,41-54,59,111H,7-28,30-33,80-81H2,1-6H3,(H2,82,112)(H2,83,113)(H2,84,114)(H2,85,117)(H,90,93)(H,94,129)(H,95,133)(H,96,121)(H,97,118)(H,98,122)(H,99,130)(H,100,124)(H,101,131)(H,102,132)(H,103,125)(H,104,119)(H,105,120)(H,106,123)(H,107,127)(H,108,128)(H,109,126)(H,115,116)(H4,86,87,91)(H4,88,89,92)/t36?,37-,38-,39+,41-,42-,43-,44?,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,59?/m0/s1
  • Molecular Formula: C79H131 N31 O24 S4
  • Molecular Structure:CAS No:24345-16-2 Apamin

Related products

Search by region :

Select to

24345-16-2 Apamin

  • Apamin
  • Germany chemcube UG [Manufacturer]
  • Tel: +49 (22 08) 7 75 04 06
  • Fax: +49 (22 08) 7 75 02 30 /
    +49 (32 12) 1 00 74 76
  • Address: chemcube UG
    Salierweg 1
    53859 Niederkassel
    Germany null,nullGermany
Contact Supplier

24345-16-2 Apamin

  • Apamin
  • United States Chem-Impex International, Inc. [Manufacturer]
  • Tel: 630 766 2112
  • Fax: 630 766 2218
  • Address: 935 Dillon Drive Wood Dale IL 60191 USA ,nullUnited States
Contact Supplier

24345-16-2 APAMIN

  • APAMIN
  • United States INTERNATIONAL LABORATORY LIMITED [Manufacturer]
  • Tel: ( 650 ) 278-9963
  • Fax: ( 650 ) 589-2786
  • Address: 1067 SNEATH LN SAN BRUNO CA 94066, USA SAN BRUNOUNITED STATES SAN BRUNO,nullUnited States
Contact Supplier

24345-16-2 Apamin

  • Apamin, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

24345-16-2 Apamin

Contact Supplier

24345-16-2 SC-200994 APAMIN

  • United States Santa Cruz Biotechnology, Inc. [Manufacturer]
  • Tel: 831-457-3800/ 800-457-3801
  • Fax: 831-457-3801
  • Address: Santa Cruz Biotechnology, Inc.
    2145 Delaware Ave.
    Santa Cruz, CA 95060 null,nullUnited States
Contact Supplier

24345-16-2 APAMIN

  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland null,nullSwitzerland
Contact Supplier

24345-16-2 APAMIN

  • United States American Peptide Company, Inc. [Manufacturer]
  • Tel: 800-926-8272/ 408-733-7604
  • Fax: 888-670-0070
  • Address: Headquarters
    American Peptide Company, Inc.
    777 East Evelyn Ave
    Sunnyvale, CA 94086
    Tel: 800-926-8272; 408-733-7604
    Fax: 888-670-0070; 408-733-7603 null,nullUnited States
Contact Supplier

24345-16-2 Apamin

  • Apamin
  • United States LKT Laboratories, Inc [Manufacturer]
  • Tel: (888)-558-5227
  • Fax:
  • Address: 2233 University Ave. West 55114-1600 St. PaulUNITED STATES 55114-1600 St. Paul,nullUnited States
Contact Supplier

24345-16-2 1652 APAMIN

  • United States Tocris Bioscience [Manufacturer]
  • Tel: (800) 421-3701/ (636) 207-7651
  • Fax: (800) 483-1993 / (636) 207-7683
  • Address: Tocris Bioscience
    16144 Westwoods Business Park
    Ellisville, Missouri 63021
    USA null,nullUnited States
Contact Supplier

Select to

1/2
1 2 Next
References of Apamin
Title: Apamin
CAS Registry Number: 24345-16-2
Molecular Formula: C79H131N31O24S4
Molecular Weight: 2027.34
Percent Composition: C 46.80%, H 6.51%, N 21.42%, O 18.94%, S 6.33%
Literature References: Neurotoxic polypeptide consisting of 18 amino acid residues and 2 disulfide bridges. Comprises about 2% by wt of the dried venom of Apis mellifica (mellifera), the honey bee. Isoln: E. Habermann, K. G. Reiz, Naturwissenschaften 51, 61 (1964); eidem, Biochem. Z. 341, 451 (1965). Structure: P. Haux et al., Z. Physiol. Chem. 348, 737 (1967); R. Shipolini et al., Chem. Commun. 1967, 679. Conformation: R. C. Hider, U. Ragnarsson, FEBS Lett. 111, 189 (1980); B. Busetta, ibid. 112, 138 (1980). Solution structure: J. H. B. Pease, D. E. Wemmer, Biochemistry 27, 8491 (1988). Solid-phase synthesis: J. van Rietschoten et al., Eur. J. Biochem. 56, 35 (1975); B. E. B. Sandberg, U. Ragnarsson, Int. J. Pept. Protein Res. 11, 238 (1978). Pharmacology: Wellheoner, Arch. Pharmakol. Exp. Pathol. 262, 29 (1969). Biochemistry: E. Habermann, K. G. Reiz, Biochem. Z. 343, 192 (1965). Action on CNS: E. Habermann, D. Cheng-Raude, Toxicon 13, 465 (1975). Binding and toxicity studies: C. Labbé-Jullié et al., Eur. J. Biochem. 196, 639 (1991). Review: E. Habermann, Science 177, 314-322 (1972); C. Granier, J. van Rietschoten, in Natural Toxins, D. Eaker, T. Wadstr?m, Eds. (Pergamon, New York, 1980) pp 481-486; E. Habermann, Pharmacol. Ther. 25, 255-270 (1984).
Properties: Highly basic compd. Pharmacologic activity destroyed by oxidn with performic acid. LD50 i.v. in mice: 4 mg/kg (Habermann, Reiz); LD50 intracerebroventricularly in mice: 12 ng/animal (Labbé-Jullié).
Toxicity data: LD50 i.v. in mice: 4 mg/kg (Habermann, Reiz); LD50 intracerebroventricularly in mice: 12 ng/animal (Labbé-Jullié)