Home > Name List By e > ethyl 2-amino-6-benzyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate

CAS No 24237-54-5 , ethyl
2-amino-6-benzyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate

  • Name: ethyl
    2-amino-6-benzyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate
  • Synonyms: ethyl
    2-amino-6-benzyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate; Dimaten; 24237-54-5;Nonflamin (free base); ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate;
  • CAS Registry Number:
  • Density: 1.256 g/cm3
  • EINECS: 246-102-0
  • Molecular Weight: 316.4179
  • InchiKey: PFENFDGYVLAFBR-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H20N2O2S/c1-2-21-17(20)15-13-8-9-19(11-14(13)22-16(15)18)10-
    12-6-4-3-5-7-12/h3-7H,2,8-11,18H2,1H3
  • Molecular Formula: C17H20N2O2S
  • Molecular Structure:CAS No:24237-54-5 ethyl<br />2-amino-6-benzyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate

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References of ethyl
2-amino-6-benzyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate
Title: Tinoridine
CAS Registry Number: 24237-54-5
CAS Name: 2-Amino-4,5,6,7-tetrahydro-6-(phenylmethyl)thieno[2,3-c]pyridine-3-carboxylic acid ethyl ester
Synonyms: 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid ethyl ester; 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine; ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
Manufacturers' Codes: Y-3642
Molecular Formula: C17H20N2O2S
Molecular Weight: 316.42
Percent Composition: C 64.53%, H 6.37%, N 8.85%, O 10.11%, S 10.13%
Literature References: Prepn: M. Nakanishi et al., DE 1812404; eidem, US 3563997 (1969, 1971 both to Yoshitomi). Pharmacological studies: M. Nakanishi et al., J. Pharm. Soc. Jpn. 90, 272-334 (1970), C.A. 73, 54504t-54510s (1970); eidem, Arzneim.-Forsch. 20, 998, 1004 (1970); Yakuri to Chiryo 2, 1028 (1974). Protective effect vs carbon tetrachloride hepatotoxicity: H. Yasuda et al., Toxicol. Appl. Pharmacol. 52, 407 (1980).
Properties: Slightly sol in H2O, mp 112-113°. LD50 in mice, rats (mg/kg): 5400, >10200 orally; 1600, 1250 i.p. (Nakanishi, 1970).
Melting point: mp 112-113°
Toxicity data: LD50 in mice, rats (mg/kg): 5400, >10200 orally; 1600, 1250 i.p. (Nakanishi, 1970)
 
Derivative Type: Hydrochloride
CAS Registry Number: 25913-34-2
Trademarks: Dimaten (Promeco); Nonflamin (Yoshitomi)
Molecular Formula: C17H20N2O2S.HCl
Molecular Weight: 352.88
Percent Composition: C 57.86%, H 6.00%, N 7.94%, O 9.07%, S 9.09%, Cl 10.05%
Properties: Yellowish white to yellow powder, mp 234-235° (dec). Practically odorless with a bitter taste. Slightly sol in methanol; very slightly sol in water, ether, acetone, benzene. LD50 orally in mice: 1601 mg/kg (Nakanishi, 1974).
Melting point: mp 234-235° (dec)
Toxicity data: LD50 orally in mice: 1601 mg/kg (Nakanishi, 1974)
 
Therap-Cat: Analgesic; antipyretic; anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Arylcarboxylic Acids; Analgesic (Non-Narcotic); Antipyretic.