Home > Name List By other > (3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3, 4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a...

CAS No 23930-19-0 , (3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,
4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one

  • Name: (3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,
    4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one
  • Synonyms: Alfaxalone; Alfaxalonum [INN-Latin]; 5alpha-Pregnan-3alpha-ol-11,20-dione; Alfaxalona [INN-Spanish]; GR 2/234; 23930-19-0;(3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,
    4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one;
  • CAS Registry Number:
  • Transport: UN 2811 6.1/PG 3
  • Flash Point: 251°C
  • Boiling Point: 468.1°C at 760 mmHg
  • Density: 1.112g/cm3
  • Refractive index: 1.532
  • Safety Statements: Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits acrid smoke and fumes.
  • Hazard Symbols: Xn
  • Flash Point: 251°C
  • Molecular Weight: 332.47698
  • InchiKey: DUHUCHOQIDJXAT-OLVMNOGESA-N
  • InChI: InChI=1S/C21H32O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,
    2)19(15)18(24)11-21(16,17)3/h13-17,19,23H,4-11H2,1-3H3/t13-,14+,15-,16+,
    17-,19+,20-,21+/m0/s1
  • Risk Statements: 22
  • Molecular Formula: C21H32O3
  • Molecular Structure:CAS No:23930-19-0 (3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,<br />4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one

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23930-19-0 AXALONE; (3A,5A)-3-HYDROXY-PREGNANE-11,20-DIONE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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23930-19-0 Alfaxalone

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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23930-19-0 Alfaxalone

  • China Haihang Industry Co., Ltd. null
  • Tel: +86-(531)-88032799
  • Fax: +86-(531)-85821093
  • Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100, null,nullChina
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23930-19-0 Alfaxalone

  • India Manus Aktteva null
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, null,nullIndia
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23930-19-0 3046 ALPHAXALONE

  • United States Tocris Bioscience [Manufacturer]
  • Tel: (800) 421-3701/ (636) 207-7651
  • Fax: (800) 483-1993 / (636) 207-7683
  • Address: Tocris Bioscience
    16144 Westwoods Business Park
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23930-19-0 Alfaxalone

  • United States Tocris Bioscience [Manufacturers]
  • Tel: +1-(800)-421-3701
  • Fax: +1-(800)-483-1993
  • Address: 16144 Westwoods Business Park, Ellisville, Missouri 63021, null,MissouriUnited States
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23930-19-0 Pregnane-11,20-dione,3-hydroxy-, (3a,5a)-

  • United States STERALOIDS [Manufacturers]
  • Tel: 401 848-5422
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23930-19-0 Alphaxalone

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  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
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    Germany null,nullGermany
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23930-19-0 Alphaxalone

  • Alphaxalone
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
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    Hong Kong null,nullHong kong
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References of (3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,
4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one
Title: Alfaxalone
CAS Registry Number: 23930-19-0
CAS Name: (3a,5a)-3-Hydroxypregnane-11,20-dione
Synonyms: alphaxalone
Manufacturers' Codes: GR-2/234
Molecular Formula: C21H32O3
Molecular Weight: 332.48
Percent Composition: C 75.86%, H 9.70%, O 14.44%
Literature References: Prepn: Nagata et al., Helv. Chim. Acta 42, 1399 (1959); Browne, Kirk, J. Chem. Soc. C 1969, 1653; Davis et al., DE 2030402; ZA 7003861 (both 1971 to Glaxo), C.A. 75, 20793n, 64114w (1971). Mass spectral data: Ende, Spiteller, Monatsh. Chem. 102, 929 (1971). Review of pharmacology and clinical efficacy of mixture with alfadolone acetate, q.v.: Postgrad. Med. J. 48, Suppl. 2, 1-139 (1972). See also Child et al.; Campbell et al.; Br. J. Anaesth. 43, 2-24 (1971); Lancet 1, 888 (1972). Pharmacology and toxicity data: M. I. Al-Khawashki et al., J. Egypt. Med. Assoc. 62, 191 (1979).
Properties: Colorless prisms from ether, mp 172-174°. [a]D26 +113.4° (c = 1.2 in chloroform). LD50 i.v. in mice: 43 mg/kg (Al-Khawashki).
Melting point: mp 172-174°
Optical Rotation: [a]D26 +113.4° (c = 1.2 in chloroform).
Toxicity data: LD50 i.v. in mice: 43 mg/kg (Al-Khawashki)
 
Derivative Type: Mixture with alfadolone acetate
CAS Registry Number: 8067-82-1
Synonyms: Alphadione; alfadione
Manufacturers' Codes: CT-1341
Trademarks: Alfatésin (Glaxo); Althesin (Glaxo); Saffan (Mallinckrodt)
Properties: LD50 in mice (mg/kg): 140 i.p., 47 i.v. (Al-Khawashki).
Toxicity data: LD50 in mice (mg/kg): 140 i.p., 47 i.v. (Al-Khawashki)
 
Therap-Cat: Combination with alfadolone acetate as anesthetic (intravenous).
Therap-Cat-Vet: Combination with alfadolone acetate as anesthetic (intravenous).
Keywords: Anesthetic (Intravenous).