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CAS No 23887-46-9 , 1-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-(3,4,
5-trimethoxyphenyl)prop-2-en-1-one

  • Name: 1-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-(3,4,
    5-trimethoxyphenyl)prop-2-en-1-one
  • Synonyms: BRN 0903854; 23887-46-9; EINECS 245-928-9;Cinepazidum [INN-Latin]; Cinepazida [INN-Spanish];1-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-(3,4,
    5-trimethoxyphenyl)prop-2-en-1-one;
  • CAS Registry Number:
  • Melting Point: 170 ~ 175ºC
  • Density: 1.2 g/cm3
  • Refractive index: 1.574
  • EINECS: 245-928-9
  • Molecular Weight: 417.49864
  • InchiKey: RCUDFXMNPQNBDU-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H31N3O5/c1-28-18-14-17(15-19(29-2)22(18)30-3)6-7-20(26)25-
    12-10-23(11-13-25)16-21(27)24-8-4-5-9-24/h6-7,14-15H,4-5,8-13,16H2,1-3H3
  • Molecular Formula: C22H31N3O5
  • Molecular Structure:CAS No:23887-46-9 1-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-(3,4,<br />5-trimethoxyphenyl)prop-2-en-1-one
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23887-46-9 Cinepazide

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China null,nullChina
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23887-46-9 2-Propen-1-one,1-[4-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1-piperazinyl]-3-(3,4,5-trimethoxyphenyl)-

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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23887-46-9 Cinepazide

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China null,nullChina
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23887-46-9 Cinepazide

  • Cinepazide 23887-46-9 B121339
  • China bepharm ltd. null
  • Tel: 86-21-51816456
  • Address: 128 Xiangyin Road, Room C320-321 Yangpu District, Shanghai 200433, China null,nullChina
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23887-46-9 Cinepazide

  • Cinepazide, 99.0%Min
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
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23887-46-9 Cinepazide

  • Cinepazide, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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23887-46-9 Cinepazide

  • Cinepazide
  • China Pharmasi Chemicals Co.Ltd [Manufacturer]
  • Tel: +86-21-67752521
  • Fax: +86-21-57819315
  • Address: Pharmasi Chemicals Co.Ltd
    Address: Room 903,
    JIAHE business building,
    songjiang,shanghai,china null,nullChina
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23887-46-9 Cinepazide

  • Cinepazide, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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23887-46-9 Cinepazide

  • China China Langchem Inc. null
  • Tel: +86-(21)-58956006
  • Fax: +86-(21)-58956100
  • Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203, null,nullChina
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23887-46-9 Cinepazide

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
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References of 1-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-(3,4,
5-trimethoxyphenyl)prop-2-en-1-one
Title: Cinepazide
CAS Registry Number: 23887-46-9
CAS Name: 1-[2-Oxo-2-(1-pyrrolidinyl)ethyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]piperazine
Synonyms: 1-[(1-pyrrolidinylcarbonyl)methyl]-4-(3,4,5-trimethoxycinnamoyl)piperazine; 1-[4-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1-piperazinyl]-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one; 1-[4-[(3¢,4¢,5¢-trimethoxycinnamoyl)-1-piperazinyl]acetyl]pyrrolidine
Molecular Formula: C22H31N3O5
Molecular Weight: 417.50
Percent Composition: C 63.29%, H 7.48%, N 10.06%, O 19.16%
Literature References: Prepn: BE 730345; C. P. Fauran et al., US 3634411 (1969, 1972 both to Delalande); C. P. Fauran, M. J. Turin, Chim. Ther. 4, 290 (1969). Pharmacology: G. Huguet et al., ibid. 293; E. Marmo et al., Farmaco Ed. Prat. 28, 132 (1973); B. M. Pourrias et al., Therapie 29, 29, 43 (1974).
 
Derivative Type: Maleate
CAS Registry Number: 26328-04-1
Manufacturers' Codes: MD-67350
Trademarks: Brendil (Daiichi); Vasodistal (Delalande)
Molecular Formula: C22H31N3O5.C4H4O4
Molecular Weight: 533.57
Percent Composition: C 58.53%, H 6.61%, N 7.88%, O 26.99%
Properties: Crystals from abs ethanol, mp 135°. LD50 in mice, rats (mg/kg): 1000, 1310 orally; 617, 414 i.v. (Pourrias).
Melting point: mp 135°
Toxicity data: LD50 in mice, rats (mg/kg): 1000, 1310 orally; 617, 414 i.v. (Pourrias)
 
Therap-Cat: Vasodilator (peripheral).
Keywords: Vasodilator (Peripheral).