Title: Aluminum Hydroxide
CAS Registry Number: 21645-51-2
Synonyms: Aluminum hydrate; aluminum trihydrate; hydrated alumina
Molecular Formula: AlH3O3
Molecular Weight: 78.00
Percent Composition: Al 34.59%, H 3.88%, O 61.54%
Line Formula: Al(OH)3
Literature References: Prepn and properties: Dominé-Berges,
Ann. Chim. [12]
5, 106 (1950); Hennig,
Chem. Tech. 1, 66 (1949),
C.A. 44, 965f (1950);
Gmelins, Aluminum (8th ed.)
35B, pp 98-132 (1934); Becher in
Handbook of Preparative Inorganic Chemistry vol. 1, G. Brauer, Ed. (Academic Press, New York, 2nd ed., 1963) pp 820-821; Wagner,
ibid. vol. 2 (1965) pp 1652-1654. Comparative pharmacology and clinical use of antacids: F. W. Green, Jr.
et al., Am. J. Hosp. Pharm. 32, 425 (1975). Clinical comparison with calcium carbonate as phosphate binder in chronic renal failure: R. H. K. Mak
et al., Br. Med. J. 291, 623 (1985). Review of use as vaccine adjuvant: W. Nicklas,
Res. Immunol. 143, 489-494 (1992).
Properties: Usually obtained as a white, bulky, amorphous powder. Practically insol in water, but sol in alkaline aq solns or in HCl, H2SO4 and other strong acids in the presence of some water. Forms gels on prolonged contact with water. Absorbs acids, CO2.
Derivative Type: Aluminum hydroxide gel
Trademarks: Aldrox (Am. Home); ALternaGEL (J & J-Merck); Aludyal (Sandoz); Amphojel (Wyeth-Ayerst); Cremorin (Sanofi Winthrop); Pepsamar (Sanofi Winthrop); Uracid (HÝsle)
Properties: White, viscous suspension. May also be used as the dried gel.
Use: Adsorbent; emulsifier; ion-exchanger; in chromatography; mordant in dyeing; filtering medium; manuf glass, fire clay, paper, pottery, printing inks, lubricating compositions, detergents; waterproofing fabrics; in antiperspirants, dentifrices. Vaccine adjuvant.
Therap-Cat: Antacid; antihyperphosphatemic.
Therap-Cat-Vet: Antacid.
Keywords: Antacid; Antihyperphosphatemic.