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CAS No 2062-78-4 , 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one

  • Name: 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one
  • Synonyms: pimozida; 2062-78-4; Halomonth; Opiran; Neoperidole; Pimozidum [INN-Latin];3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one; Pimozidum;Orap; McN-JR-6238;
  • CAS Registry Number:
  • Transport: 3249
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.224g/cm3
  • Refractive index: 1.596
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: °C
  • EINECS: 218-171-7
  • Molecular Weight: 461.546166
  • InchiKey: YVUQSNJEYSNKRX-UHFFFAOYSA-N
  • InChI: InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-
    3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,
    24-25H,3-4,15-19H2,(H,31,34)
  • Risk Statements: S36
  • Molecular Formula: C28H29F2N3O
  • Molecular Structure:CAS No:2062-78-4 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one

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2062-78-4 Pimozide

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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2062-78-4 Pimozide

  • Pimozide, 99.54%
  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland null,nullSwitzerland
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2062-78-4 PIMOZIDE

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany null,nullGermany
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2062-78-4 Pimozide

  • Pimozide, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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2062-78-4 PIMOZIDE

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
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2062-78-4 Pimozide

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2062-78-4 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one

  • 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-onePimozide
  • United Kingdom Tocris Bioscience [Manufacturer]
  • Tel: + 44 (0)117 916 3333
  • Fax: + 44 (0)117 916 3344
  • Address: Tocris Bioscience Tocris House Hung Road BS11 9XJ BristolUNITED KINGDOM BS11 9XJ Bristol,nullUnited Kingdom
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2062-78-4 PIMOZIDE

  • PIMOZIDE
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
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2062-78-4 PIMOZIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
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References of 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one
Title: Pimozide
CAS Registry Number: 2062-78-4
CAS Name: 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Synonyms: 1-[1-[4,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone; 1-[4,4-di-(4-fluorophenyl)butyl]-4-(2-oxo-1-benzimidazolinyl)piperidine
Manufacturers' Codes: R-6238
Trademarks: Orap (Janssen); Opiran (Cassenne)
Molecular Formula: C28H29F2N3O
Molecular Weight: 461.55
Percent Composition: C 72.86%, H 6.33%, F 8.23%, N 9.10%, O 3.47%
Literature References: Prepn: Janssen, FR M3695 (1965 to Janssen), C.A. 66, 115709t (1967). Pharmacological studies: Janssen et al., Arzneim.-Forsch. 18, 261, 279, 282 (1968). Metabolism in rats: Soudijn, Wijngaarden, Life Sci. 8, 291 (1969). Clinical experience: Poldinger, Curr. Ther. Res. 13, 23 (1971). Pimozide blocks establishment but not expression of amphetamine-produced environment-specific conditioning: R. J. Beninger, B. L. Hahn, Science 220, 1304 (1983). Use in treatment of acute schizophrenia: B. Shopsin, G. Selzer, Curr. Ther. Res. 21, 755 (1977); in treatment of chronic schizophrenia: F. Kline et al., ibid. 768. In management of Gilles de la Tourette's syndrome: M. S. Ross, H. Moldofsky, Lancet 1, 103 (1977); A. K. Shapiro, E. Shapiro, Am. J. Psychiatry 140, 1235 (1983); eidem, J. Am. Acad. Child Psychiatry 23, 161 (1984).
Properties: Microcrystals, mp 214-218°. Weak base, pKa 7.32. Almost insol in water (<0.01 mg/ml). Very slightly sol in dil aq solns of organic and mineral acids (<5 mg/ml).
Melting point: mp 214-218°
pKa: pKa 7.32
Therap-Cat: Antipsychotic.
Keywords: Antidyskinetic; Antipsychotic.