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CAS No 204656-20-2 , liraglutide

  • Name: liraglutide
  • Synonyms: liraglutide;Liraglutide;
  • CAS Registry Number:
  • Molecular Weight: 0
  • InChI: InChI=1/C172H265N43O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-53-128(223)193-112(59-64-132(227)228)148(244)180-68-41-40-50-111(154(250)199-116(62-67-135(233)234)155(251)204-120(73-100-44-33-31-34-45-100)160(256)214-140(93(11)19-2)168(264)192-97(15)146(242)201-122(76-103-79-183-108-49-39-38-48-106(103)108)158(254)203-118(72-90(5)6)159(255)212-138(91(7)8)166(262)200-110(52-43-70-182-172(177)178)150(246)184-81-129(224)194-109(51-42-69-181-171(175)176)149(245)187-84-137(237)238)196-144(240)95(13)189-143(239)94(12)191-153(249)115(58-63-127(174)222)195-130(225)82-185-152(248)114(61-66-134(231)232)198-156(252)117(71-89(3)4)202-157(253)119(75-102-54-56-105(221)57-55-102)205-163(259)124(85-216)208-165(261)126(87-218)209-167(263)139(92(9)10)213-162(258)123(78-136(235)236)206-164(260)125(86-217)210-170(266)142(99(17)220)215-161(257)121(74-101-46-35-32-36-47-101)207-169(265)141(98(16)219)211-131(226)83-186-151(247)113(60-65-133(229)230)197-145(241)96(14)190-147(243)107(173)77-104-80-179-88-188-104/h31-36,38-39,44-49,54-57,79-80,88-99,107,109-126,138-142,183,216-221H,18-30,37,40-43,50-53,58-78,81-87,173H2,1-17H3,(H2,174,222)(H,179,188)(H,180,244)(H,184,246)(H,185,248)(H,186,247)(H,187,245)(H,189,239)(H,190,243)(H,191,249)(H,192,264)(H,193,223)(H,194,224)(H,195,225)(H,196,240)(H,197,241)(H,198,252)(H,199,250)(H,200,262)(H,201,242)(H,202,253)(H,203,254)(H,204,251)(H,205,259)(H,206,260)(H,207,265)(H,208,261)(H,209,263)(H,210,266)(H,211,226)(H,212,255)(H,213,258)(H,214,256)(H,215,257)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H,235,236)(H,237,238)(H4,175,176,181)(H4,177,178,182)/t93-,94-,95-,96-,97-,98+,99+,107-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,138-,139-,140-,141-,142-/m0/s1
  • Molecular Formula: C172H265N43O51
  • Molecular Structure:CAS No:204656-20-2 liraglutide

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  • CAS Number: 204656-20-2 Molecular formula: C172H265N43O51 Molar mass 3751.20 Sequence : H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ -Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH Application ar...
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    References of liraglutide
    Title: Liraglutide
    CAS Registry Number: 204656-20-2
    Synonyms: N26-(Hexadecanoyl-g-glutamyl)-(34-arginine)GLP-1-(7-37)-peptide; Lys26(Ne-(g-glutamyl-(Na-hexadecanoyl))), Arg34-GLP-1(7-37)
    Manufacturers' Codes: NN-2211
    Molecular Formula: C172H265N43O51
    Molecular Weight: 3751.20
    Percent Composition: C 55.07%, H 7.12%, N 16.06%, O 21.75%
    Literature References: Acylated derivative of glucagon-like peptide 1, q.v. Prepn: L. B. Knudsen et al., WO 9808871; idem et al., US 6268343 (1998, 2001 both to Novo Nordisk); eidem, J. Med. Chem. 43, 1664 (2000). Clinical effect on glucose and insulin homeostasis: H. Agerso, P. Vicini, Eur. J. Pharm. Sci. 19, 141 (2003). Clinical pharmacokinetics: B. Elbrond et al., Diabetes Care 25, 1398 (2002). Clinical trial in type 2 diabetes: S. Madsbad et al., ibid. 27, 1335 (2004); M. N. Feinglos et al., Diabetic Med. 22, 1016 (2005).
    Therap-Cat: Antidiabetic.
    Keywords: Antidiabetic; Hormones/Analogs.