Home > Name List By other > [4-(4-amino-6, 7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone

CAS No 19216-56-9 , [4-(4-amino-6,
7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone

  • Name: [4-(4-amino-6,
    7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone
  • Synonyms: Prazosina; Lentopres; Prazosinum; Minipress; Prazosine [INN-French];[4-(4-amino-6,
    7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone;Furazosin; Prazosinum [INN-Latin]; Prazosine;
  • CAS Registry Number:
  • Melting Point: 278-280 ºC
  • Flash Point: 339.9°C
  • Boiling Point: 638.4°Cat760mmHg
  • Density: 1.352g/cm3
  • Refractive index: 1.651
  • Safety Statements: Human systemic effects by ingestion of very small amounts: somnolence, hallucinations, distorted perceptions, changes in motor activity, decreased blood pressure, nausea or vomiting, and kidney effects. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 339.9°C
  • EINECS: 242-885-8
  • Molecular Weight: 383.40114
  • InchiKey: IENZQIKPVFGBNW-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)
    24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,
    22)
  • Molecular Formula: C19H21N5O4
  • Molecular Structure:CAS No:19216-56-9 [4-(4-amino-6,<br />7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone

Related products

Search by region :

Select to

19216-56-9 prazosin

  • IUPAC NAME-2-[4-(2-furoyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine MOLECULAR FORMULA-C19H21N5O4 MOLAR MASS-383.401 g/mol Prazosin is also useful in treating urinary hesitancy associated with prostatic hyperplasia, blocking alpha-1 receptors, w...
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Plot No: 04, Mayur Park Road, Harsool Aurangabad,MaharashtraIndia
Contact Supplier

19216-56-9 Methanone,[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-

Contact Supplier

19216-56-9 PRAZOSIN

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
Contact Supplier

19216-56-9 Prazosin

Contact Supplier

19216-56-9 PRAZOSIN

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
Contact Supplier

19216-56-9 Prazosin

  • China Pharmasi Chemicals Co.,Ltd null
  • Fax: +86-21-57819315
  • Address: Room 205, Renlesancun50-29,songjiang,shanghai,China null,nullChina
Contact Supplier

19216-56-9 Methanone,[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-

  • China KINFON PHARMACEUTICAL AND CHEMICAL CO.LTD [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: +86-23-8650081
  • Fax: +86-23-8650081
  • Address: 7F,Commercial Building, No.3 Nanping West Road,Nan null,nullChina
Contact Supplier

19216-56-9 Prazosin

Contact Supplier

19216-56-9 1-(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)-4-(2-FURANYLCARBONYL)PIPERAZINE HIDROCHLORIDE PRAZOSIN

Contact Supplier

Select to

1/1
References of [4-(4-amino-6,
7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone
Title: Prazosin
CAS Registry Number: 19216-56-9
CAS Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine
Synonyms: 2-[4-(2-furoyl)piperazin-1-yl]-4-amino-6,7-dimethoxyquinazoline; furazosin
Molecular Formula: C19H21N5O4
Molecular Weight: 383.40
Percent Composition: C 59.52%, H 5.52%, N 18.27%, O 16.69%
Literature References: a1-Adrenergic blocker. Prepn: GB 1156973; Hess, US 3511836 (1969, 1970 both to Pfizer); NL 7206067 (1972 to Brocades-Stheeman), C.A. 78, 72180s (1973); E. Honkanen et al., J. Heterocycl. Chem. 17, 797 (1980). Pharmacology and clinical data: Scriabine et al., Experientia 24, 1150 (1968); Cohen, J. Clin. Pharmacol. J. New Drugs 10, 408 (1970). Pharmacokinetics: P. Jaillon, Clin. Pharmacokinet. 5, 365 (1980). HPLC determn in biological fluids: R. K. Bhamra et al., J. Chromatogr. 380, 216 (1986). Clinical evaluation in Raynaud's phenomenon: I. J. Russell, J. A Lessard, J. Rheumatol. 12, 94 (1985); in dysuria with benign prostatic hypertrophy: A. LeDuc et al., Urol. Int. 45, Suppl. 1, 56 (1990). Book: Prazosin: Pharmacology, Hypertension and Congestive Heart Failure, M. D. Rawlins, Ed. (Grune & Stratton, New York, 1981) 143 pp. Review of pharmacology and therapeutic use: W. F. Stanaszek et al., Drugs 25, 339-384 (1983); J. L. Reid, J. Vincent, Cardiology 73, 164-174 (1986). Comprehensive description: L. J. Kostek, Anal. Profiles Drug Subs. 18, 351-378 (1989).
Properties: Crystals, mp 278-280°.
Melting point: mp 278-280°
 
Derivative Type: Hydrochloride
CAS Registry Number: 19237-84-4
Manufacturers' Codes: CP-12299-1
Trademarks: Alpress LP (Pfizer); Duramipress (Durachemie); Eurex (Labaz); Hypovase (Pfizer); Minipress (Pfizer); Peripress (Pfizer); Sinetens (Erba)
Molecular Formula: C19H21N5O4.HCl
Molecular Weight: 419.86
Percent Composition: C 54.35%, H 5.28%, N 16.68%, O 15.24%, Cl 8.44%
Properties: uv max (methanolic 0.01N HCl): 246, 329 nm (aM 137 ±3, 27.6 ±0.3). Soly at ambient temp (mg/ml): acetone 0.0072, methanol 6.4, ethanol 0.84, dimethylformamide 1.3, dimethylacetamide 1.2, water (pH~3.5) 1.4, chloroform 0.041.
Absorption maximum: uv max (methanolic 0.01N HCl): 246, 329 nm (aM 137 ±3, 27.6 ±0.3)
 
Therap-Cat: Antihypertensive.
Keywords: a-Adrenergic Blocker; Antihypertensive; Quinazoline Derivatives.