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CAS No 182485-36-5 , Phosphinic acid,P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)-

  • Name: Phosphinic acid,P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)-
  • Synonyms: Phosphinic acid,P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)-; TPMPA;Phosphinicacid, methyl(1,2,3,6-tetrahydro-4-pyridinyl)- (9CI);
  • CAS Registry Number:
  • Safety Statements:
    WGK Germany 3
  • Molecular Weight: 161.14
  • Molecular Formula: C6H12 N O2 P
  • Molecular Structure:CAS No:182485-36-5 Phosphinic acid,P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)-

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182485-36-5 TPMPA

  • TPMPA
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182485-36-5 TPMPA; (1,2,5,6-TETRAHYDRO(PYRIDIN-4-YL))METHYLPHOSPHINIC ACID

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182485-36-5 TPMPA

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182485-36-5 (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid

  • (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acidTPMPA
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182485-36-5 TPMPA

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References of Phosphinic acid,P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)-
Title: TPMPA
CAS Registry Number: 182485-36-5
CAS Name: Methyl (1,2,3,6-tetrahydro-4-pyridinyl)phosphinic acid
Synonyms: (1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid
Molecular Formula: C6H12NO2P
Molecular Weight: 161.14
Percent Composition: C 44.72%, H 7.51%, N 8.69%, O 19.86%, P 19.22%
Literature References: Selective antagonist for GABAc receptors. Prepn: Y. Murata et al., Bioorg. Med. Chem. Lett. 6, 2073 (1996); R. Miledi et al., US 5627169 (1997 to Univ. California). Design and in vitro pharmacology: D. Ragozzino et al., Mol. Pharmacol. 50, 1024 (1996). Specificity vs human receptors and alternate synthesis: M. Chebib et al., Eur. J. Pharmacol. 357, 227 (1998). Use as antagonist: A. Rozzo et al., Neuroscience 90, 1085 (1999).
Properties: Off-white solid from ethanol, mp 252-254°. Soly in water 16 mg/ml. Insol in DMSO.
Melting point: mp 252-254°
Use: Neurochemical tool.