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CAS No 16960-16-0 , a1-24-Corticotropin

  • Name: a1-24-Corticotropin
  • Synonyms: HumanACTH (1-24); Cortrosinta;a1-24-Corticotropin; 10: PN: WO03051390 PAGE: 52 claimed protein; Porcine ACTH (1-24); Synacthene-retard;(1-24)a-ACTH; Tetracosactrin; Synacthene; 1-24corticotropin (human); Ba 30920; Cortrophin S; b-Corticotrophin-(1-24)-tetracosapeptide; Tetracosapeptide; Tetracosactid; Cortrosyn;Nuvacthen Depot; b1-24-Tetracosactide;Synacthen; Cosyntropin;Corticotropin-(1-24); 8: PN: WO0069900 SEQID: 7 unclaimedsequence; PN: WO9952928 SEQID: 9 claimed protein; Synecthen; ACTHa1-24;Tetracosactide; L-Proline, L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-glutamyl-L-a-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-; 2136: PN: WO03060071 SEQID: 2198unclaimed; a1-24-Adrenocorticotropic hormone; a1-24-ACTH; 20: PN:WO2006052468 SEQID: 2 claimed sequence;b1-24-ACTH; 1-24 ACTH (human); 4: PN: WO2004045592 SEQID: 3 unclaimed sequence; Adrenocorticotropin(1-24); Actholain; b1-24-Corticotropin; ACTH1-24; 7: PN:US20090175821 SEQID: 7 claimed protein; Ba 36716;
  • CAS Registry Number:
  • Density: 1.476g/cm3
  • Refractive index: 1.681
  • EINECS: 241-031-1
  • Molecular Weight: 2933.437
  • InChI: InChI=1/C136H210N40O31S/c1-75(2)109(127(200)154-71-106(181)156-88(31-13-17-52-137)114(187)158-89(32-14-18-53-138)115(188)159-91(35-21-56-149-134(142)143)116(189)164-96(37-23-58-151-136(146)147)131(204)175-60-25-39-104(175)126(199)173-111(77(5)6)128(201)163-90(33-15-19-54-139)120(193)171-110(76(3)4)129(202)169-101(65-80-43-47-84(180)48-44-80)132(205)176-61-26-40-105(176)133(206)207)172-125(198)103-38-24-59-174(103)130(203)95(34-16-20-55-140)157-107(182)70-153-113(186)99(66-81-68-152-87-30-12-11-29-85(81)87)167-117(190)92(36-22-57-150-135(144)145)160-121(194)98(63-78-27-9-8-10-28-78)166-123(196)100(67-82-69-148-74-155-82)168-118(191)93(49-50-108(183)184)161-119(192)94(51-62-208-7)162-124(197)102(73-178)170-122(195)97(165-112(185)86(141)72-177)64-79-41-45-83(179)46-42-79/h8-12,27-30,41-48,68-69,74-77,86,88-105,109-111,152,177-180H,13-26,31-40,49-67,70-73,137-141H2,1-7H3,(H,148,155)(H,153,186)(H,154,200)(H,156,181)(H,157,182)(H,158,187)(H,159,188)(H,160,194)(H,161,192)(H,162,197)(H,163,201)(H,164,189)(H,165,185)(H,166,196)(H,167,190)(H,168,191)(H,169,202)(H,170,195)(H,171,193)(H,172,198)(H,173,199)(H,183,184)(H,206,207)(H4,142,143,149)(H4,144,145,150)(H4,146,147,151)/t86-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,109-,110-,111-/m0/s1
  • Molecular Formula: C136H210 N40 O31 S
  • Molecular Structure:CAS No:16960-16-0 a1-24-Corticotropin
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16960-16-0 a1-24-Corticotropin

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16960-16-0 a1-24-Corticotropin

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16960-16-0 a1-24-Corticotropin

  • China GL Biochem(Shanghai) Ltd. [Manufacturer, Other]
  • Tel: +86-021-61263400
  • Fax: +86-021-61263399
  • Address: 519 Ziyue Road,shanghai 200241,china null,nullChina
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16960-16-0 a1-24-Corticotropin

  • China Leap Labchem Co.Ltd [Manufacturer]
  • Tel: +86-571-87756549
  • Fax: +86-571-87755464
  • Address: Leap Labchem Co.,Ltd
    Zhongtian Mansion,No.173,
    Yugu Road Xihu District,
    Hangzhou,310007,PR,China null,nullChina
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16960-16-0 a1-24-Corticotropin

  • China GL Biochem(Shanghai)Ltd. [Manufacturers]
  • Tel: +86-10-86637865
  • Fax: +86-10-62273627
  • Address: 519 Ziyue Road,Shanghai Minhang ZiZhu Science-Based Industrial Park Shanghai,ShanghaiChina
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16960-16-0 Tetracosactide

  • China Nanjing Samwon International Limited [Importer/Exporter]
  • Tel: +86-(25)-84873444
  • Fax: +86-(25)-84507436
  • Address: 1108, BLDG B, New Century Plaza, No 1, South Taiping Rd., Nanjing, Jiangsu 210002, Nanjing,JiangsuChina
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16960-16-0 Cosyntropin

  • China Yongyi Biotechnology Co,.Ltd [Importer/Exporter]
  • Tel: +86-21-60904639
  • Fax: +86-21-60904609
  • Address: Suite 3005, City Gateway, No.398 North CaoXi Road, XuHui District, Shanghai 200030, China. null,nullChina
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16960-16-0 ACTH (1-24), HUMAN

  • United States American Peptide Company, Inc. [Manufacturer]
  • Tel: 800-926-8272/ 408-733-7604
  • Fax: 888-670-0070
  • Address: Headquarters
    American Peptide Company, Inc.
    777 East Evelyn Ave
    Sunnyvale, CA 94086
    Tel: 800-926-8272; 408-733-7604
    Fax: 888-670-0070; 408-733-7603 null,nullUnited States
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16960-16-0 ACTH (1-24) (HUMAN)

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany null,nullGermany
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16960-16-0 a1-24-Corticotropin

  • France NeoMPS SA [Manufacturers]
  • Tel: +33 (0)3 88 79 08 79
  • Fax: +33 (0)3 88 79 18 56
  • Address: 7 rue de Boulogne 67100 Strasbourg · France Strasbourg,StrasbourgFrance
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References of a1-24-Corticotropin
Title: Cosyntropin
CAS Registry Number: 16960-16-0
CAS Name: a1-24-Corticotropin
Synonyms: b1-24-corticotropin; tetracosactide
Trademarks: Cortrosyn (Amphastar)
Molecular Formula: C136H210N40O31S
Molecular Weight: 2933.44
Percent Composition: C 55.68%, H 7.22%, N 19.10%, O 16.91%, S 1.09%
Literature References: Synthetic polypeptide corresponding to the first 24 amino acids of ACTH, q.v. Identification of activity: R. G. Shepherd et al., J. Am. Chem. Soc. 78, 5067 (1956). Synthesis: H. Kappeler, R. Schwyzer, Helv. Chim. Acta 44, 1136 (1961); eidem, ibid. 46, 1550 (1963); solid-state synthesis: R. Matsueda et al., J. Am. Chem. Soc. 97, 2573 (1975). Assessment of hormone levels for adrenal function in cats: M. E. Peterson et al., Res. Vet. Sci. 37, 331 (1984); in dogs: L. A. Frank et al., Domest. Anim. Endocrinol. 24, 43 (2003). Review as diagnostic aid in assessment of secondary adrenal insufficiency: T. A. M. Abdu, R. N. Clayton, Curr. Opin. Endocrinol. Diabetes 7, 116-121 (2000); in primary or secondary adrenal insufficiency: R. I. Dorin et al., Ann. Intern. Med. 139, 194-204, E205-E206 (2003).
 
Derivative Type: Hexaacetate
CAS Registry Number: 22633-88-1
CAS Name: a1-24-Corticotropin hexaacetate (salt)
Trademarks: Synacthen (Novartis)
Properties: [a]D22 -88 ±2° (c = 0.511 in 1% acetic acid). uv max (0.1 N NaOH): 283, 289 nm (e 8550, 8810).
Optical Rotation: [a]D22 -88 ±2° (c = 0.511 in 1% acetic acid)
Absorption maximum: uv max (0.1 N NaOH): 283, 289 nm (e 8550, 8810)
 
Therap-Cat: Diagnostic aid (adrenal function).
Therap-Cat-Vet: Diagnostic aid (adrenal function).
Keywords: Diagnostic Aid.