CAS No 16679-58-6 , N-[1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-
oxopentan-2-yl]-1-[7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-
benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,
8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide Search by region : Germany

Name: N-[1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-
oxopentan-2-yl]-1-[7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-
benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,
8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Synonyms: N-[1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-
oxopentan-2-yl]-1-[7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-
benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,
8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide; Desmopressinum; DDAVP; Adiuretin; Desmopressine; Desmopresina; Adiuretin SD;DESMOPRESSIN; Minirin; Deamino Arginine Vasopressin;
CAS Registry Number:16679-58-6
Density: 1.56 g/cm³
Refractive index: 1.713
EINECS: 240-726-7
Molecular Weight: 1069.21696
InchiKey: NFLWUMRGJYTJIN-UHFFFAOYSA-N
InChI: InChI=1S/C46H64N14O12S2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43
(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-
23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)
57-31(42(69)55-29)20-25-6-2-1-3-7-25/h1-3,6-7,10-13,28-34,61H,4-5,8-9,
14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,
71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52)
Molecular Formula: C₄₆H₆₄N₁₄O₁₂S₂
Molecular Structure:

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References of N-[1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-
oxopentan-2-yl]-1-[7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-
benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,
8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide

Title: Desmopressin
CAS Registry Number: 16679-58-6
CAS Name: 1-(3-Mercaptopropanoic acid)-8-D-arginine vasopressin
Synonyms: 8-D-arginine-1-(3-mercaptopropanoic acid) vasopressin; 1-desamino-8-D-arginine vasopressin
Molecular Formula: C46H64N14O12S2
Molecular Weight: 1069.22
Percent Composition: C 51.67%, H 6.03%, N 18.34%, O 17.96%, S 6.00%
Literature References: Synthetic analog of vasopressin, q.v., with antidiuretic activity and decreased pressor effects. Improves hemostasis by increasing plasma levels of von Willebrand factor, factor VIII and tissue plasminogen activator, q.q.v. Prepn: M. Zaoral et al., FR 1540536; eidem, US 3497491 (1968, 1970 both to Ceskoslovenska Akad. Ved). Syntheses: R. L. Huguenin, R. A. Boissonnas, Helv. Chim. Acta 49, 695 (1966); M. Zaoral et al., Collect. Czech. Chem. Commun. 32, 1250 (1967). Review of clinical experience in bleeding disorders: P. M. Mannucci, Blood 90, 2515-2521 (1997); in treatment of nocturnal enuresis: P. E. V. van Kerrebroeck, BJU Int. 89, 420-425 (2002); of mechanism of hemostatic effects: J. E. Kaufmann, U. M. Vischer, J. Thromb. Haemostasis 1, 682-689 (2003).
Properties: [a]D25 +85.5 ± 2° (calculated for the free peptide).
Optical Rotation: [a]D25 +85.5 ± 2° (calculated for the free peptide)

Derivative Type: Monoacetate
CAS Registry Number: 62288-83-9
Trademarks: Adiuretin SD (Ferring); DDAVP (Ferring); Desmospray (Ferring); Minirin (Ferring); Octim (Ferring); Octostim (Ferring); Presinex (Pliva); Stimate (ZLB Behring)
Molecular Formula: C46H64N14O12S2.C2H4O2
Molecular Weight: 1129.27
Percent Composition: C 51.05%, H 6.07%, N 17.36%, O 19.84%, S 5.68%
Literature References: Occurs as the trihydrate.

Therap-Cat: Antidiuretic; hemostatic.
Keywords: Antidiuretic; Hemostatic.