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CAS No 162808-62-0 , Caspofungin

  • Name: Caspofungin
  • Synonyms: Caspofungin;PneumocandinB0,1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)-;
  • CAS Registry Number:
  • Flash Point: 805.4°C
  • Boiling Point: 1408.1°Cat760mmHg
  • Density: 1.36g/cm3
  • Refractive index: 1.623
  • Flash Point: 805.4°C
  • Molecular Weight: 1093.31
  • InChI: InChI=1/C52H88N10O15/c1-5-28(2)24-29(3)12-10-8-6-7-9-11-13-39(69)56-34-26-38(68)46(55-22-21-54)60-50(75)43-37(67)19-23-61(43)52(77)41(36(66)18-20-53)58-49(74)42(45(71)44(70)31-14-16-32(64)17-15-31)59-48(73)35-25-33(65)27-62(35)51(76)40(30(4)63)57-47(34)72/h14-17,28-30,33-38,40-46,55,63-68,70-71H,5-13,18-27,53-54H2,1-4H3,(H,56,69)(H,57,72)(H,58,74)(H,59,73)(H,60,75)/t28?,29?,30-,33-,34+,35+,36-,37+,38-,40?,41+,42?,43+,44+,45+,46-/m1/s1
  • Molecular Formula: C52H88N10O15
  • Molecular Structure:CAS No:162808-62-0 Caspofungin

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162808-62-0 Caspofungin

  • Caspofungin is an antifungal drug, the first of a new class termed the echinocandins from Merck & Co., Inc. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. Caspofung...
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162808-62-0 Caspofungin

  • Name;Caspofungin CAS # 162808-62-0, Caspofungin Molecular Formula;C52H88N10O15 Molecular Weight;1093.31 CAS Registry Number;162808-62-0
  • Min. Order: 10000
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162808-62-0 Caspofungine

  • Caspofungine
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162808-62-0 Caspofungin

  • Product Name: Caspofungin Synonyms: Caspofungine;CASPOFUNGIN;CASPORFUNGIN;Aids058650;Aids-058650;Cancidas (tm);m991;Caspofungin .CH3COOH CAS: 162808-62-0 MF: C53H89N9O15 MW: 1092.33
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162808-62-0 Caspofungin,162808-62-0

  • Product Name: Caspofungin Synonyms: Caspofungine;CASPOFUNGIN;CASPORFUNGIN;Aids058650;Aids-058650;Cancidas (tm);m991;Caspofungin .CH3COOH CAS: 162808-62-0 MF: C53H89N9O15 MW: 1092.33 EINECS: Mol File: 162808-62-0.mol
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162808-62-0 Pneumocandin B0,1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-

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162808-62-0 Caspofungin

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162808-62-0 Caspofungin

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162808-62-0 Caspofungin

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162808-62-0 Caspofungin

  • Caspofungin, Min 99%
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References of Caspofungin
Title: Caspofungin
CAS Registry Number: 162808-62-0
CAS Name: 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0
Molecular Formula: C52H88N10O15
Molecular Weight: 1093.31
Percent Composition: C 57.13%, H 8.11%, N 12.81%, O 21.95%
Literature References: Semisynthetic echinocandin antifungal that inhibits 1,3-b-D-glucan synthase which is required for cell wall synthesis. Prepn: J. M. Balkovec et al., WO 9421677; eidem, US 5378804 (1994, 1995 both to Merck & Co.). HPLC/MS determn in plasma: C. M. Chavez-Eng et al., J. Chromatogr. B 721, 229 (1999). Clinical study vs amphotericin B, q.v. in Candida esophagitis: A. Villanueva et al., Clin. Infect. Dis. 33, 1529 (2001). Review of in vitro antifungal activity, pharmacology and clinical development: A. H. Groll, T. J. Walsh, Expert Opin. Invest. Drugs 10, 1545-1558 (2001); A. Hoang, Am. J. Health-Syst. Pharm. 58, 1206-1214 (2001).
 
Derivative Type: Acetate
CAS Registry Number: 179463-17-3
Manufacturers' Codes: MK-0991
Trademarks: Cancidas (Merck & Co.)
Molecular Formula: C52H88N10O15.2C2H4O2
Molecular Weight: 1213.42
Percent Composition: C 55.43%, H 7.97%, N 11.54%, O 25.05%
Properties: Hygroscopic white to off-white powder. Freely sol in water, methanol; slightly sol in ethanol.
 
Therap-Cat: Antifungal.
Keywords: Antifungal (Antibiotics); Echinocandins.