Home > Name List By 5 > 5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2- carboxylic acid India

CAS No 16110-51-3 , 5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-
carboxylic acid Search by region : India

  • Name: 5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-
    carboxylic acid
  • Synonyms: Frenasma; CHEBI:59773; 16110-51-3; Lomudal; Cromoglicic acid; Aararre; Lomusol; Cromoglycate;5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-
    carboxylic acid; Lomudas;cromolyn;
  • CAS Registry Number:
  • Melting Point: 241-242 ºC
  • Density: 1.623
  • Refractive index: 1.681
  • Safety Statements: 26-36
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 240-279-8
  • Molecular Weight: 468.36654
  • InchiKey: IMZMKUWMOSJXDT-UHFFFAOYSA-N
  • InChI: InChI=1S/C23H16O11/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)
    28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30/h1-8,11,24H,9-10H2,
    (H,27,28)(H,29,30)
  • Risk Statements: 36/37/38
  • Molecular Formula: C23H16O11
  • Molecular Structure:CAS No:16110-51-3 5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-<br />carboxylic acid

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16110-51-3 Cromoglicic acid

  • IUPAC NAME-5,5′-(2-hydroxypropane-1,3-diyl)bis(oxy)bis(4-oxo-4H-chromene-2-carboxylic acid) MOLECULAR FORMULA-C23H16O11 MOLAR MASS-468.367 g/mol
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References of 5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-
carboxylic acid
Title: Cromolyn
CAS Registry Number: 16110-51-3
CAS Name: 5,5￠-[(2-Hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-4H-1-benzopyran-2-carboxylic acid]
Synonyms: 5,5￠-[(2-hydroxytrimethylene)dioxy]bis(4-oxo-4H-1-benzopyran-2-carboxylic acid); 5,5￠-(2-hydroxytrimethylenedioxy)bis(4-oxochromene-2-carboxylic acid); 1,3-bis(2-carboxychromon-5-yloxy)-2-hydroxypropane; 1,3-di(2-carboxy-4-oxochromen-5-yloxy)propan-2-ol; cromoglycic acid
Molecular Formula: C23H16O11
Molecular Weight: 468.37
Percent Composition: C 58.98%, H 3.44%, O 37.58%
Literature References: Chromone complex which blocks mast cell degranulation. Prepn: NL 6603997; C. Fitzmaurice, T. B. Lee, US 3419578 (1966, 1968 both to Fisons). Metabolism: M. J. Ashton et al., Toxicol. Appl. Pharmacol. 26, 319 (1973). Mechanism of action: T. C. Theoharides et al., Science 207, 80 (1980); R. G. Alvarez et al., Agents Actions 11, 94 (1981). Toxicology in primates: J. E. Beach et al., Toxicol. Appl. Pharmacol. 57, 367 (1981). Clinical study in allergic conjunctivitis: G. A. Friday et al., Am. J. Ophthalmol. 95, 169 (1983). Review of pharmacology and clinical use: G. G. Shapiro, P. Konig, Pharmacotherapy 5, 156-170 (1985). Review: J. S. G. Cox in Pharmacological and Biochemical Properties of Drug Substances vol. 1, M. E. Goldberg, Ed. (Am. Pharm. Assoc., Washington, DC, 1977) pp 277-310; W. Storms, M. A. Kaliner, J. Asthma 42, 79-89 (2005).
Properties: mp 241-242° (dec).
Melting point: mp 241-242° (dec)
 
Derivative Type: Monohydrate
Properties: Colorless crystals from ethanol + ether, mp 216-217° (dec).
Melting point: mp 216-217° (dec)
 
Derivative Type: Disodium salt
CAS Registry Number: 15826-37-6
Synonyms: Cromolyn sodium; disodium cromoglycate; DSCG
Manufacturers' Codes: FPL-670
Trademarks: Alloptrex (Fabre); Allergocrom (Ursapharm); Colimune (Sanofi-Aventis); Cromabak (Th?); Cromadoses (Th?); Cromedil (Europhta); Cromogen (Ivax); Cromoptic (Chauvin); Duracroman (Merck KGaA); Gastrofrenal (Sigma-Tau); Hay-Crom (Ivax); Intal (Sanofi-Aventis); Intercron (Zambon); Lomudal (Sanofi-Aventis); Lomupren (Sanofi-Aventis); Lomusol (Sanofi-Aventis); Multicrom (Menarini); Nalcrom (Sanofi-Aventis); Nalcron (Sanofi-Aventis); Nasalcrom (Pharmacia & Upjohn); Ophtacalm (Chauvin); Opticrom (Sanofi-Aventis); Rynacrom (Sanofi-Aventis); Vividrin (Mann)
Molecular Formula: C23H14Na2O11
Molecular Weight: 512.33
Percent Composition: C 53.92%, H 2.75%, Na 8.97%, O 34.35%
Properties: Hygroscopic. Freely sol in water (100 mg/ml at 20°). Practically insol in chloroform and alcohol. LD50 in mice, rats (mg/kg): >8000 orally (Cox).
Toxicity data: LD50 in mice, rats (mg/kg): >8000 orally (Cox)
 
Therap-Cat: Antiasthmatic; antiallergic.
Therap-Cat-Vet: Antiallergic.
Keywords: Antiallergic; Antiasthmatic (Nonbronchodilator).