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CAS No 160337-95-1 , Insulin (human),21A-glycine-30Ba-Larginine- 30Bb-L-arginine-

  • Name: Insulin (human),21A-glycine-30Ba-Larginine- 30Bb-L-arginine-
  • Synonyms: Insulin (human),21A-glycine-30Ba-Larginine- 30Bb-L-arginine- ;
  • CAS Registry Number:
  • Molecular Weight: 6050
  • InChI: InChI=1S/C41H50N6O2/c1-38(2,3)24-40(7,8)28-20-26(36(48)34(22-28)46-42-30-15-11-12-16-31(30)43-46)19-27-21-29(41(9,10)25-39(4,5)6)23-35(37(27)49)47-44-32-17-13-14-18-33(32)45-47/h11-18,20-23,48-49H,19,24-25H2,1-10H3
  • Molecular Formula: C267H404N72O78S6
  • Molecular Structure:CAS No:160337-95-1 Insulin (human),21A-glycine-30Ba-Larginine- 30Bb-L-arginine-

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160337-95-1 Insulin (human),21A-glycine-30Ba-Larginine- 30Bb-L-arginine-

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160337-95-1 INSULIN GLARGINE

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References of Insulin (human),21A-glycine-30Ba-Larginine- 30Bb-L-arginine-
Title: Insulin Glargine
CAS Registry Number: 160337-95-1
CAS Name: 21A-Glycine-30Ba-L-arginine-30Bb-L-arginine-insulin (human)
Synonyms: [Gly(A21),Arg(B31),Arg(B32)]insulin (human)
Manufacturers' Codes: HOE-901
Trademarks: Lantus (Aventis)
Literature References: Long-acting analog of human insulin produced by recombinant DNA technology. Prepn: M. D?rschug, DE 3837825; idem, US 5656722 (1990, 1997 both to Hoechst). Characterization of receptor interaction: L. Berti et al., Horm. Metab. Res. 30, 123 (1998). Clinical pharmacodynamics: L. Heinemann et al., Diabetes Care 23, 644 (2000); pharmacokinetics: D. R. Owens et al., ibid. 813. Clinical trial in type 1 diabetics: R. E. Ratner et al., ibid. 639. Review of clinical experience: P. S. Gillies et al., Drugs 59, 253-260 (2000).
Properties: pI 6.7. Sol in acid pH. Insol at physiological pH.
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic; Hormones/Analogs.