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CAS No 159519-65-0 , Enfuvirtide

  • Name: Enfuvirtide
  • Synonyms: T 20;1: PN:WO0155439 SEQID: 1 claimed protein;636: PN: WO0151673 FIGURE: 54claimed protein;6: PN: WO2004091542 SEQID: 7 claimed protein;Pentafuside;Fuzeon;Enfuvirtide;GP 41-127-162AA;1: PN: WO0224149 PAGE: 24 claimed protein;414: PN: WO0164013 FIGURE: 24 claimed protein;1: PN: US20030044411 PAGE: 10 claimed protein;1: PN: US20020146415 PAGE: 10claimed protein;DP 178;11:PN: WO2008112736 SEQID: 11 claimed protein;T 20 (peptide);
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.59g/cm3
  • Flash Point: °C
  • Molecular Weight: 4491.90
  • InChI: InChI=1S/C204H301N51O64/c1-20-102(15)166(253-195(310)137(75-100(11)12)239-200(315)150(93-258)251-190(305)143(82-112-90-215-95-219-112)248-203(318)167(103(16)21-2)254-196(311)138(76-101(13)14)240-201(316)151(94-259)252-204(319)168(105(18)260)255-197(312)139(221-106(19)261)78-108-45-47-113(262)48-46-108)202(317)233-131(58-68-164(280)281)178(293)228-130(57-67-163(278)279)182(297)250-149(92-257)198(313)232-125(52-62-155(210)266)179(294)245-145(84-157(212)268)191(306)229-124(51-61-154(209)265)175(290)224-122(49-59-152(207)263)173(288)226-126(53-63-159(270)271)176(291)222-120(43-31-33-69-205)172(287)244-144(83-156(211)267)192(307)231-127(54-64-160(272)273)177(292)225-123(50-60-153(208)264)174(289)227-128(55-65-161(274)275)180(295)235-134(72-97(5)6)185(300)237-133(71-96(3)4)184(299)230-129(56-66-162(276)277)181(296)236-135(73-98(7)8)187(302)247-147(86-165(282)283)194(309)223-121(44-32-34-70-206)171(286)241-140(79-109-87-216-117-40-28-25-37-114(109)117)183(298)220-104(17)170(285)249-148(91-256)199(314)238-136(74-99(9)10)186(301)242-142(81-111-89-218-119-42-30-27-39-116(111)119)189(304)246-146(85-158(213)269)193(308)243-141(80-110-88-217-118-41-29-26-38-115(110)118)188(303)234-132(169(214)284)77-107-35-23-22-24-36-107/h22-30,35-42,45-48,87-90,95-105,120-151,166-168,216-218,256-260,262H,20-21,31-34,43-44,49-86,91-94,205-206H2,1-19H3,(H2,207,263)(H2,208,264)(H2,209,265)(H2,210,266)(H2,211,267)(H2,212,268)(H2,213,269)(H2,214,284)(H,215,219)(H,220,298)(H,221,261)(H,222,291)(H,223,309)(H,224,290)(H,225,292)(H,226,288)(H,227,289)(H,228,293)(H,229,306)(H,230,299)(H,231,307)(H,232,313)(H,233,317)(H,234,303)(H,235,295)(H,236,296)(H,237,300)(H,238,314)(H,239,315)(H,240,316)(H,241,286)(H,242,301)(H,243,308)(H,244,287)(H,245,294)(H,246,304)(H,247,302)(H,248,318)(H,249,285)(H,250,297)(H,251,305)(H,252,319)(H,253,310)(H,254,311)(H,255,312)(H,270,271)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)/t102-,103-,104-,105+,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,166-,167-,168-/m0/s1
  • Molecular Formula: C204H301N51O64
  • Molecular Structure:CAS No:159519-65-0 Enfuvirtide

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    References of Enfuvirtide
    Title: Enfuvirtide
    CAS Registry Number: 159519-65-0
    Synonyms: Pentafuside
    Manufacturers' Codes: DP-178; T-20
    Trademarks: Fuzeon (Roche)
    Molecular Formula: C204H301N51O64
    Molecular Weight: 4491.88
    Percent Composition: C 54.55%, H 6.75%, N 15.90%, O 22.80%
    Literature References: HIV fusion inhibitor. Synthetic, 36 amino acid peptide corresponding to a region of gp41, the transmembrane subunit of the HIV-1 envelope protein. Prepn and biological activity: D. P. Bolognesi et al., WO 9428920; eidem, US 5464933 (1994, 1995 both to Duke Univ.); C. T. Wild et al., Proc. Natl. Acad. Sci. USA 91, 9770 (1994). Mechanism of action study: R. A. Furuta et al., Nat. Struct. Biol. 5, 276 (1998). Clinical pharmacokinetics: J. M. Kilby et al., AIDS Res. Hum. Retroviruses 18, 685 (2002). Review of development: N. Press et al., Curr. Opin. Anti-Infect. Invest. Drugs 1, 171-178 (1999); of clinical evaluations: A. Pozniak, J. HIV Ther. 6, 91-94 (2001).
    Therap-Cat: Antiviral.
    Keywords: HIV Fusion Inhibitor; Antiviral.