Title: Paraflutizide
CAS Registry Number: 1580-83-2
CAS Name: 6-Chloro-3-[(4-Fluorophenyl)methyl]-3,4-dihydro-2
H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Synonyms: 1,1-dioxo-3-(
p-fluorophenylmethyl)-3,4-dihydro-6-chloro-1,2,4-benzothiadiazine-7-sulfonamide
Manufacturers' Codes: LD-3612
Molecular Formula: C14H13ClFN3O4S2
Molecular Weight: 405.85
Percent Composition: C 41.43%, H 3.23%, Cl 8.74%, F 4.68%, N 10.35%, O 15.77%, S 15.80%
Literature References: Prepn:
BE 620829 (1962 to Lab. Dausse),
C.A. 58, 12585g (1963), corresponds to
GB 961641;
FR M1374 (1962 to Lab. Dausse),
C.A. 58, 2462c (1963). Synthesis: J. Klosa,
J. Prakt. Chem. 33, 298 (1966).
Properties: Crystals from 50% alcohol, mp 238-240°.
Melting point: mp 238-240°
Therap-Cat: Diuretic.
Keywords: Antihypertensive; Thiazides and Analogs; Diuretic; Thiazides and Analogs.
Status: This monograph has been retired and is no longer subject to revision or update.