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CAS No 133-67-5 , 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1λ

  • Name: 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1λ
  • Synonyms: Cretonin; Chlopolidine; Diurese;6,2,
    4-benzothiadiazine-7-sulfonamide; Naqua; Aponorin; Achletin; Metahydrin;Trichloromethiazide;6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1λ Trichlormetazid;
  • CAS Registry Number:
  • Melting Point: 248-250 ºC
  • Flash Point: 335.6°C
  • Boiling Point: 631.3°Cat760mmHg
  • Density: 1.748
  • Refractive index: 1.625
  • Safety Statements: R42/43
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 335.6°C
  • EINECS: 205-118-8
  • Molecular Weight: 380.65582
  • InchiKey: LMJSLTNSBFUCMU-UHFFFAOYSA-N
  • InChI: InChI=1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,
    18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)
  • Risk Statements: S36
  • Molecular Formula: C8H8Cl3N3O4S2
  • Molecular Structure:CAS No:133-67-5 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1λ
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133-67-5 TRICHLOROMETHIAZIDE; 99%

  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
  • Fax: +49 721 95061-80
  • Address: Im Schlehert 10
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    Germany null,nullGermany
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133-67-5 TRICHLORMETHIAZIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
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  • Address: Rm.902 Longyin Plaza,
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    (N)Nanjing 210009,China null,nullChina
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133-67-5 trichlormethiazide

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133-67-5 TRICHLORMETHIAZIDE

  • United States ACIC [Manufacturer]
  • Tel: 800-265-6727/ 519-751-3668
  • Fax: 519-751-1378
  • Address: 11772 West Sample Road,
    Coral Springs, Florida, 33065 USA null,nullUnited States
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133-67-5 Trichlormethiazide

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133-67-5 trichlormethiazide

  • China SINOCHEM NINGBO LTD. [Manufacturer]
  • Tel: +86-574-87260209/ +86-574-87348868
  • Fax: +86-574-87342797, 87262630
  • Address: 21 Jiangxia St., Ningbo 315000
    Zhejiang China null,nullChina
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133-67-5 Trichlormethiazide

  • United States CBSCHEM LIMITED null
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 null,nullUnited States
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References of 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1λ
Title: Trichlormethiazide
CAS Registry Number: 133-67-5
CAS Name: 6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Synonyms: 6-chloro-3-dichloromethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide; 3-dichloromethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide; 3-dichloromethylhydrochlorothiazide; hydrotrichlorothiazide; trichloromethiazide
Trademarks: Achletin (Toyama); Anatran (Tobishi); Anistadin (Maruko); Aponorin (Kodama); Carvacron (Taiyo); Diurese (Am. Urologicals); Esmarin (Merck KGaA); Fluitran (Shionogi); Flutra (Schering); Intromene (Teikoku); Kubacron (Kayaku); Metahydrin (HMR); Naqua (Schering); Salurin (Syntex); Tachionin (Sana); Tolcasone (RPR); Triflumen (Serono)
Molecular Formula: C8H8Cl3N3O4S2
Molecular Weight: 380.66
Percent Composition: C 25.24%, H 2.12%, Cl 27.94%, N 11.04%, O 16.81%, S 16.85%
Literature References: Prepn: deStevens et al., Experientia 16, 113 (1960); Sherlock et al., ibid. 184. Toxicity: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: Crystals from methanol + acetone + water, dec 266-273°, also reported as 248-250°. Soly (mg/ml) at 25°: water 0.8; ethanol 21; methanol 60. LD50 orally in rats: >20000 mg/kg (Goldenthal).
Toxicity data: LD50 orally in rats: >20000 mg/kg (Goldenthal)
Therap-Cat: Diuretic; antihypertensive.
Therap-Cat-Vet: Diuretic.
Keywords: Antihypertensive; Thiazides and Analogs; Diuretic; Thiazides and Analogs.