Title: Folescutol
CAS Registry Number: 15687-22-6
CAS Name: 6,7-Dihydroxy-4-(4-morpholinylmethyl)-2
H-1-benzopyran-2-one
Synonyms: 6,7-dihydroxy-4-(morpholinomethyl)coumarin; 4-morpholinomethylescutol; pholescutol
Molecular Formula: C14H15NO5
Molecular Weight: 277.27
Percent Composition: C 60.64%, H 5.45%, N 5.05%, O 28.85%
Literature References: Prepn by the reaction of 4-chloromethyl-6,7-dihydroxycoumarin with morpholine:
FR M2035 (1963 to Labs. Dausse),
C.A. 60, 4113 (1964). Pharmacological study: J. P. Tarayre
et al., Ann. Pharm. Fr. 33, 467 (1975).
Properties: Crystals from 50% ethanol, mp 232°.
Melting point: mp 232°
Derivative Type: Hydrochloride
CAS Registry Number: 36002-19-4
Manufacturers' Codes: LD-2988
Trademarks: Covalan (Dausse)
Molecular Formula: C14H15NO5.HCl
Molecular Weight: 313.73
Percent Composition: C 53.60%, H 5.14%, N 4.46%, O 25.50%, Cl 11.30%
Properties: Crystals from 75% ethanol, mp 259-261°.
Melting point: mp 259-261°
Therap-Cat: Capillary protectant.
Keywords: Vasoprotectant.
Status: This monograph has been retired and is no longer subject to revision or update.