Home > Name List By 2 > 2,2-dichloro-N-[(1R,2R)-1, 3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

CAS No 15318-45-3 , 2,2-dichloro-N-[(1R,2R)-1,
3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

  • Name: 2,2-dichloro-N-[(1R,2R)-1,
    3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
  • Synonyms: (+)-Thiamphenicol; Macphenicol;Thiophenicol;2,2-dichloro-N-[(1R,2R)-1,
    3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide; 15318-45-3; Thiamphenicolum; Thiamcol; Thiocymetin; Dextrosulphenidol;
  • CAS Registry Number:
  • Melting Point: 163-166 °C
  • Flash Point: 374.7°C
  • Boiling Point: 695.9°Cat760mmHg
  • Density: 1.491g/cm3
  • Refractive index: 1.589
  • Safety Statements: Poison by intravenous route. Moderately toxic by subcutaneous route. Mildly toxic by ingestion. Human systemic effects by an unspecified route: sleep disorders, dermatitis, nausea or vomiting. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl−. See also CHLORAMPHENICOL.
  • Flash Point: 374.7°C
  • EINECS: 239-355-3
  • Molecular Weight: 356.2222
  • InchiKey: OTVAEFIXJLOWRX-NXEZZACHSA-N
  • InChI: InChI=1S/C12H15Cl2NO5S/c1-21(19,
    20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,
    1H3,(H,15,18)/t9-,10-/m1/s1
  • Molecular Formula: C12H15Cl2NO5S
  • Molecular Structure:CAS No:15318-45-3 2,2-dichloro-N-[(1R,2R)-1,<br />3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
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15318-45-3 Thiamphenicol

  • Thiamphenicol CAS No.: 15318-45-3 EINECS No.: 239-355-3 Grade Standard: Medicine Grade Purity: 99% MF: C12H15Cl2NO5S Molecular Weight:401.22 Usage: thiamphenicol a class of broad-spectrum antibiotic chloramphenicol, against Gram-positive bacteria, su...
  • Min. Order: 500
  • China Hubei Yuancheng Group [Manufacturer, Trading Company]
  • Tel: 86-027-50756063
  • Address: Zhongshan Road Wuhan,HubeiChina
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15318-45-3 Thiamphenicol

  • Specifications Thiamphenicol CAS No.:15318-45-3 EINECS No.: 239-355-3 Grade Standard: Medicine Grade Purity: 99% MF: C12H15Cl2NO5S Molecular Weight:401.22 Usage: thiamphenicol a class of broad-spectrum antibiotic chloramphenicol, against Gram-positiv...
  • China Wuhan Far City Science and Technology Development Co., LTD [Distributor/Wholesaler]
  • Tel: 86-27-50756153
  • Fax: 86-027-68886696
  • Address: Wuchang District of Wuhan City, Hubei Province, 496 Zhongshan Road wuhan,HubeiChina
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15318-45-3 Thiamphenicol

  • Thiamphenicol
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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15318-45-3 Thiamphenicol

  • Product Name: Thiamphenicol Alias:Methylsulfonyl chloramphenicol CAS:15318-45-3 EINECS:239-355-3 MF:C12H15Cl2NO5S MW:356.22 Assay: 99% Standard: EP/BP/JP/CP Melting point: 163-166°C Density: 1.491g/cm3 Boiling point: 695.9° Cat760mmHg Storage: -20° C...
  • FOB Price: USD1 - 2 /
  • China Yuanchen [Trading Company]
  • Tel: 86-027-50756024
  • Address: No. 496 Zhongshan Road, Wuchang, Wuhan, Hubei Wuhan, Hubei,HubeiChina
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15318-45-3 Thiamphenicol

  • Names: Thiamphenicol CAS No.: 15318-45-3 EINECS No.: 239-355-3 Grade Standard: Medicine Grade Purity: 99% MF: C12H15Cl2NO5S Molecular Weight:401.22 Usage: thiamphenicol a class of broad-spectrum antibiotic chloramphenicol, against Gram-positive bacte...
  • Min. Order: 3000
  • China Wuhan Yuancheng Gongchuang Technology Co.Ltd [Manufacturer]
  • Tel: 86-27-50756085
  • Fax: --
  • Address: No.496, Wuchang District, wuhan,HubeiChina
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15318-45-3 Thiamphenicol roy@yccreate.com

  • Names: Thiamphenicol CAS No.: 15318-45-3 EINECS No.: 239-355-3 Grade Standard: Medicine Grade Purity: 99% MF: C12H15Cl2NO5S Molecular Weight:401.22 Usage: thiamphenicol a class of broad-spectrum antibiotic chloramphenicol, against Gram-positive bacte...
  • FOB Price: USD1 - 10 /
  • China Hubei Yuancheng Saichuang Technology Co. [Manufacturer, Trading Company]
  • Tel: 86-027-50756025
  • Fax: 86-027-68886696
  • Address: No. 496 Zhongshan Road, Wuchang Wuhan,HubeiChina
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15318-45-3 thiamphenicol

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15318-45-3 thiamphenicol

  • China Syntechem Co.,Ltd [Manufacturer]
  • Tel: +86-519-89882658
  • Fax: +86-519-8512 5369
  • Address: Syntechem Co.,Ltd
    18 South Zhulin Rd.
    Tianning district,Changzhou
    Jiangsu China 213022 null,nullChina
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15318-45-3 Thiamphenicol

  • China Simag Chemicals [Manufacturer]
  • Tel: +86 592 2680277
  • Fax: +86 592 2680237
  • Address: Simag Chemicals
    A-9D Atlantic sea view city,
    No.9 Hubin West Rd.,
    Xiamen China. null,nullChina
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15318-45-3 thiamphenicol

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: null Union City,CaliforniaUnited States
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References of 2,2-dichloro-N-[(1R,2R)-1,
3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
Title: Thiamphenicol
CAS Registry Number: 15318-45-3
CAS Name: 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
Synonyms: D-d-threo-2-dichloroacetamido-1-(4-methylsulfonyl)phenyl-1,3-propanediol; dextrosulphenidol
Manufacturers' Codes: Win-5063-2; 8053CB
Trademarks: Hyrazin (Kowa); Igralin (Zeria); Neomyson (Eisai); Rigelon (Dojin); Thiamcol (Morishita); Thionicol (Mohan); Thiophenicol (Clin Comar); Urfamycine (Inpharzam); Urophenil (Nippon Seiyaku)
Molecular Formula: C12H15Cl2NO5S
Molecular Weight: 356.22
Percent Composition: C 40.46%, H 4.24%, Cl 19.91%, N 3.93%, O 22.46%, S 9.00%
Literature References: Synthesis: Cutler et al., J. Am. Chem. Soc. 74, 5475 (1952); Suter et al., ibid. 75, 4330 (1953); Suter, US 2759927; US 2759970; US 2759971; US 2759972; US 2759976 (all 1956 to Sterling Drugs); GB 770277 (1957 to Parke, Davis).
Properties: Crystals, mp 164.3-166.3°. [a]D25 +12.9° (ethanol). uv max (95% ethanol): 224, 266, 274 nm (e 13,700, 800, 700). Appreciably sol in water. Soluble in alcohol.
Melting point: mp 164.3-166.3°
Optical Rotation: [a]D25 +12.9° (ethanol)
Absorption maximum: uv max (95% ethanol): 224, 266, 274 nm (e 13,700, 800, 700)
 
Derivative Type: DL-Form
CAS Registry Number: 847-25-6
Synonyms: Raceophenidol; racephenicol
Trademarks: Dexawin (Winthrop); Thiocymetin (Winthrop)
 
Therap-Cat: Antibacterial.
Therap-Cat-Vet: D-Form as antimicrobial; DL-form in control of fowl cholera.
Keywords: Antibacterial (Antibiotics); Amphenicols.