Home > Name List By 7 > 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2, 4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

CAS No 147059-72-1 , 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,
4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

  • Name: 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,
    4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
  • Synonyms: TVFX; Trovan (oral); Fluorinated quinolone; Trovafloxacin (INN); 147059-72-1; Trovafloxacin [INN];7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,
    4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid; CP-99,219;Trovan;
  • CAS Registry Number:
  • Flash Point: 335.1°C
  • Boiling Point: 630.5°Cat760mmHg
  • Density: 1.612g/cm3
  • Refractive index: 1.672
  • Flash Point: 335.1°C
  • Molecular Weight: 416.35331
  • InchiKey: WVPSKSLAZQPAKQ-SOSAQKQKSA-N
  • InChI: InChI=1S/C20H15F3N4O3/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-
    14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24/h1-4,7,10-11,16H,5-6,24H2,
    (H,29,30)/t10-,11+,16?
  • Molecular Formula: C20H15F3N4O3
  • Molecular Structure:CAS No:147059-72-1 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,<br />4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

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147059-72-1 TROVAFLOXACIN

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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147059-72-1 TROVAFLOXACIN HYDROCHLORIDE

  • Canada Synth?se AptoChem Inc. [Manufacturer]
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  • Address: Synth?se AptoChem Inc.
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147059-72-1 1,8-Naphthyridine-3-carboxylic acid,7-(6-amino-3-azabicyclo[3.1.0]hex-3- yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4- dihydro-4-oxo-,(1R,5R,6R)-

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147059-72-1 TROVAFLOXACIN

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147059-72-1 1,8-Naphthyridine-3-carboxylic acid,7-(6-amino-3-azabicyclo[3.1.0]hex-3- yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4- dihydro-4-oxo-,(1R,5R,6R)-

  • China Bo Jia Science and Technology (Wuhan) Co., Ltd. [Manufacturers]
  • Tel: 02787526690-8155
  • Fax: 86-027-87526527
  • Address: Wuhan City, Hubei Province Luo Yu Road, Hongshan No. 424 Technology Innovation Center, 14 Floor, Block A wuhan,hubeiChina
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References of 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,
4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
Title: Trovafloxacin
CAS Registry Number: 147059-72-1
CAS Name: (1a,5a,6a)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
Manufacturers' Codes: CP-99219
Molecular Formula: C20H15F3N4O3
Molecular Weight: 416.35
Percent Composition: C 57.70%, H 3.63%, F 13.69%, N 13.46%, O 11.53%
Literature References: Fluorinated quinolone antibacterial. Prepn: K. E. Brighty, US 5164402 (1992 to Pfizer). Voltammetric determn in urine and serum: J. L. Vílchez et al., J. Pharm. Biomed. Anal. 31, 465 (2003). Antibacterial spectrum in vitro: H. C. Neu, N.-X. Chin, Antimicrob. Agents Chemother. 38, 2615 (1994). Clinical pharmacokinetics: R. Teng et al., J. Antimicrob. Chemother. 36, 385 (1995). Evaluation in gonorrhea: E. W. Hook et al., Antimicrob. Agents Chemother. 40, 1720 (1996). Mechanism of hepatotoxicity: M. J. Liguori et al., Hepatology 41, 177 (2005).
 
Derivative Type: Hydrochloride
CAS Registry Number: 146961-34-4
Molecular Formula: C20H15F3N4O3.HCl
Molecular Weight: 452.81
Percent Composition: C 53.05%, H 3.56%, F 12.59%, N 12.37%, O 10.60%, Cl 7.83%
Properties: Pale yellow crystals from acetonitrile/methanol, mp 246° (dec).
Melting point: mp 246° (dec)
 
Derivative Type: Methanesulfonate
CAS Registry Number: 147059-75-4
Synonyms: Trovafloxacin mesylate
Manufacturers' Codes: CP-99219-27
Trademarks: Trovan
Molecular Formula: C20H15F3N4O3.CH3SO3H
Molecular Weight: 512.46
Percent Composition: C 49.22%, H 3.74%, F 11.12%, N 10.93%, O 18.73%, S 6.26%
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Quinolones and Analogs.