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CAS No 147-20-6 , 4-benzhydryloxy-1-methylpiperidine

  • Name: 4-benzhydryloxy-1-methylpiperidine
  • Synonyms: Allergen; Mepiben; Lyssipoll; Histyn; Neargal; Belfene;4-benzhydryloxy-1-methylpiperidine; Dayfen; Hispril; Histryl;
  • CAS Registry Number:
  • Transport: 3249
  • Density: 1.08 g/cm3
  • Refractive index: 1.587
  • Safety Statements: Poison by ingestion and intravenous routes. An eye irritant. When heated to decomposition it emits toxic fumes of NOx.
  • EINECS: 205-686-7
  • Molecular Weight: 281.39202
  • InchiKey: OWQUZNMMYNAXSL-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H23NO/c1-20-14-12-18(13-15-20)21-19(16-8-4-2-5-9-16)17-10-6-
    3-7-11-17/h2-11,18-19H,12-15H2,1H3
  • Molecular Formula: C19H23NO
  • Molecular Structure:CAS No:147-20-6 4-benzhydryloxy-1-methylpiperidine

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References of 4-benzhydryloxy-1-methylpiperidine
Title: Diphenylpyraline
CAS Registry Number: 147-20-6
CAS Name: 4-(Diphenylmethoxy)-1-methylpiperidine
Synonyms: diphenylpyrilene; 4-benzhydryloxy-N-methylpiperidine; 1-methyl-4-piperidyl benzhydryl ether; 1-methyl-4-hydroxypiperidine benzhydryl ether
Manufacturers' Codes: P-253
Molecular Formula: C19H23NO
Molecular Weight: 281.39
Percent Composition: C 81.10%, H 8.24%, N 4.98%, O 5.69%
Literature References: Prepn: L. H. Knox, R. Kapp, US 2479843 (1949 to Nopco). Pharmacokinetics: G. Graham, A. G. Bolt, J. Pharmacokinet. Biopharm. 2, 191 (1974). Clinical trial in allergic rhinitis: H. Puhakka et al., J. Int. Med. Res. 5, 37 (1977). GC determn in blood and urine: H. Hattori et al., J. Chromatogr. 581, 213 (1992).
 
Derivative Type: Hydrochloride
CAS Registry Number: 132-18-3
Trademarks: Dayfen (3M Pharma); Diafen (3M Pharma); Hispril (SKB); Histryl (SKB); Histyn (HÝsle); Kolton (Promonta); Lergoban (3M Pharma); Lergobine (3M Pharma)
Molecular Formula: C19H23NO.HCl
Molecular Weight: 317.85
Percent Composition: C 71.80%, H 7.61%, N 4.41%, O 5.03%, Cl 11.15%
Properties: Crystals from isopropanol + ether, mp 206°. Sol in water, ethanol, isopropanol. Practically insol in ether, benzene.
Melting point: mp 206°
 
Derivative Type: Hydrobromide
CAS Registry Number: 5807-87-4
Molecular Formula: C19H23NO.HBr
Molecular Weight: 362.30
Percent Composition: C 62.99%, H 6.68%, N 3.87%, O 4.42%, Br 22.05%
Literature References: Prepn: R. F. Phillips, US 2595405 (1952 to Merck & Co.).
Properties: Crystals, mp 201-202°. Soluble in water, ethanol.
Melting point: mp 201-202°
 
Derivative Type: 8-Chlorotheophyllinate
CAS Registry Number: 606-90-6
Synonyms: Piprinhydrinate; diphenylpyraline theoclate
Trademarks: Mepedyl (Glaxo)
Molecular Formula: C19H23NO.C7H7ClN4O2
Molecular Weight: 496.00
Percent Composition: C 62.96%, H 6.10%, N 14.12%, O 9.68%, Cl 7.15%
Literature References: Prepn: W. A. Schuler, DE 934890 (1955 to Promonta), C.A. 52, 20065i (1958).
Properties: White to off-white crystalline powder, mp 174-176°. Sparingly sol in water. Freely sol in alcohol.
Melting point: mp 174-176°
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Aminoalkylethers.