Home > Name List By 2 > 2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5, 6-dihydropyrido[2,3-d]pyrimidin-7-one

CAS No 145733-36-4 , 2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,
6-dihydropyrido[2,3-d]pyrimidin-7-one

  • Name: 2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,
    6-dihydropyrido[2,3-d]pyrimidin-7-one
  • Synonyms: Verdia; Tasosartan (USAN/INN); AC1Q6LAA; Tasosartan; AC1L1U5X;145733-36-4; ANA-756;2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,
    6-dihydropyrido[2,3-d]pyrimidin-7-one; S1539_Selleck; WAY-ANA-756; DB01349;
  • CAS Registry Number:
  • Flash Point: 413.1°C
  • Boiling Point: 759.4°C at 760 mmHg
  • Density: 1.328g/cm3
  • Refractive index: 1.665
  • Flash Point: 413.1°C
  • Molecular Weight: 411.45914
  • InchiKey: ADXGNEYLLLSOAR-UHFFFAOYSA-N
  • InChI: InChI=1S/C23H21N7O/c1-14-18-11-12-21(31)30(23(18)25-15(2)24-14)13-16-7-
    9-17(10-8-16)19-5-3-4-6-20(19)22-26-28-29-27-22/h3-10H,11-13H2,1-2H3,(H,
    26,27,28,29)
  • Molecular Formula: C23H21N7O
  • Molecular Structure:CAS No:145733-36-4 2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,<br />6-dihydropyrido[2,3-d]pyrimidin-7-one

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145733-36-4 Tasosartan

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145733-36-4 Pyrido[2,3-d]pyrimidin-7(6H)-one,5,8-dihydro-2,4-dimethyl-8-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-

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145733-36-4 Pyrido[2,3-d]pyrimidin-7(6H)-one,5,8-dihydro-2,4-dimethyl-8-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-

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145733-36-4 TASOSARTAN

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References of 2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,
6-dihydropyrido[2,3-d]pyrimidin-7-one
Title: Tasosartan
CAS Registry Number: 145733-36-4
CAS Name: 5,8-Dihydro-2,4-dimethyl-8-[[2￠-(1H-tetrazol-5-yl)[1,1￠-biphenyl]-4-yl]methyl]pyrido[2,3-d]pyrimidin-7(6H)-one
Manufacturers' Codes: ANA-756
Trademarks: Verdia (Am. Home)
Molecular Formula: C23H21N7O
Molecular Weight: 411.46
Percent Composition: C 67.14%, H 5.14%, N 23.83%, O 3.89%
Literature References: Selective angiotensin II type 1 (AII1)-receptor antagonist. Prepn: J. W. Ellingboe et al., US 5149699 (1992 to Am. Home); idem et al., J. Med. Chem. 37, 542 (1994). Clinical tolerability in patients with essential hypertension: S. Oparil et al., Curr. Ther. Res. 58, 930 (1997); and efficacy: J. M. Neutel et al., Am. Heart J. 137, 118 (1999).
Properties: White crystals from ethanol, mp 197-199°.
Melting point: mp 197-199°
Therap-Cat: Antihypertensive.
Keywords: Angiotensin II Receptor Antagonist; Antihypertensive; Biphenyltetrazole Derivatives.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.