Title: Bacitracin Zinc
CAS Registry Number: 1405-89-6
Synonyms: Zinc bacitracin
Trademarks: Albac (Alpharma); Baciferm (Roche)
Literature References: Prepn: H. S. Anker
et al., J. Bacteriol. 55, 249 (1948). Review of properties and formulatory characteristics: H. M. Gross,
Drug Cosmet. Ind. 75, 612 (1954);
idem et al., J. Am. Pharm. Assoc. Sci. Ed. 45, 447 (1956). Solubility data: P. J. Weiss
et al., Antibiot. Chemother. 7, 374 (1957). ELISA determn in animal feed: C. Williams
et al., Analyst 119, 427 (1994). Field trials as performance enhancer in pigs: S. C. Kyriakis
et al., Vet. Rec. 138, 489 (1996); in chickens: G. Huyghebaert, G. De Groote,
Poult. Sci. 76, 849 (1997). Clinical trial in giardiasis: B. J. Andrews
et al., Am. J. Trop. Med. Hyg. 52, 318 (1995); in prevention of wound infection: D. J. Dire
et al., Acad. Emerg. Med. 2, 4 (1995).
Properties: Creamy powder contg 1-4% H2O. Less bitter and more stable than bacitracin. Soly at about 28° (mg/ml): water 5.1; methanol 6.55; ethanol 2.0; isopropanol 0.16; ethyl acetate 1.3; chloroform 0.01; petr ether 0.025.
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial; growth promotant.
Keywords: Antibacterial (Antibiotics); Polypeptides.
