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CAS No 14028-44-5 , 8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine

  • Name: 8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine
  • Synonyms: 14028-44-5;Asendin; Desmethylloxapin; Amoxepine; Amoxapina; Defanyl; Asendis; Demolox; Moxadil;8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine;
  • CAS Registry Number:
  • Transport: 3249
  • Melting Point: 175-1760C
  • Flash Point: 238°C
  • Boiling Point: 469.9°Cat760mmHg
  • Density: 1.37g/cm3
  • Refractive index: 1.685
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 238°C
  • EINECS: 237-867-1
  • Molecular Weight: 313.78144
  • InchiKey: QWGDMFLQWFTERH-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-
    3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2
  • Risk Statements: S36
  • Molecular Formula: C17H16ClN3O
  • Molecular Structure:CAS No:14028-44-5 8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine
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14028-44-5 amoxapine

  • amoxapine 2-Chloro-11-(1-piperazinyl)dibenz[b,f][1,4]oxazepine AMOXAPINE USP STANDARD 2-Chloro-11-piperazin-1-yl-dibenzo[b,f][1,4]oxazepine
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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14028-44-5 Amoxapine

  • Amoxapine
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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14028-44-5 amoxapine

  • IUPAC NAME-2-chloro-11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazepine MOLECULAR FORMULA-C17H16ClN3O MOLAR MASS-313.781 g/mol
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Harsool Aurangabad,MaharashtraIndia

14028-44-5 Amoxapine

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14028-44-5 Amoxapine

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14028-44-5 Amoxapine

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China null,nullChina
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14028-44-5 Amoxapine

  • Amoxapine, 99.4%
  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland null,nullSwitzerland
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14028-44-5 AMOXAPINE

  • AMOXAPINE
  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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14028-44-5 Amoxapine

  • Amoxapine
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
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14028-44-5 Amoxapine

  • Amoxapine, 98.0%MIN
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
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References of 8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine
Title: Amoxapine
CAS Registry Number: 14028-44-5
CAS Name: 2-Chloro-11-(1-piperazinyl)dibenz[b,f][1,4]oxazepine
Manufacturers' Codes: CL-67772
Trademarks: Asendin (Lederle); Asendis (Wyeth); Defanyl (Lederle); Demolox (Am. Cyanamid); Moxadil (Lederle)
Molecular Formula: C17H16ClN3O
Molecular Weight: 313.78
Percent Composition: C 65.07%, H 5.14%, Cl 11.30%, N 13.39%, O 5.10%
Literature References: Prepn: J. Schmutz et al., Helv. Chim. Acta 50, 245 (1967); eidem, Chim. Ther. 2, 424 (1967); C. F. Howell et al., FR 1508536; eidem, US 3663696 (1968, 1972 both to Am. Cyanamid). Analysis of amoxapine and its metabolites by GLC: T. B. Cooper, R. G. Kelly, J. Pharm. Sci. 68, 216 (1979). X-ray crystallography: D. B. Cosulich, F. M. Lovell, Acta Crystallogr. B33, 1147 (1977). Pharmacology: E. N. Greenblatt et al., Arch. Int. Pharmacodyn. Ther. 233, 107 (1978). Clinical study: R. Takahashi et al., J. Int. Med. Res. 7, 7 (1979). Review: T. A. Ban, Psychopharmacol. Bull. 15, 22-25 (1979); E. N. Greenblatt et al., in Pharmacological and Biochemical Properties of Drug Substances vol. 2, M. E. Goldberg, Ed. (Am. Pharm. Assoc., Washington, DC, 1979) pp 1-18. Review of pharmacology and therapeutic efficacy: S. G. Jue et al., Drugs 24, 1-23 (1982).
Properties: Crystals from benzene/petr ether, mp 175-176°. LD50 in mice (mg/kg): 122 i.p.; 112 orally (Howell, 1972).
Melting point: mp 175-176°
Toxicity data: LD50 in mice (mg/kg): 122 i.p.; 112 orally (Howell, 1972)
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tricyclics.