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CAS No 14008-44-7 , 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide

  • Name: 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide
  • Synonyms: EINECS 237-818-4; 14008-44-7; EXP 999;1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide; BRN 4278585;Vogalene; RP 9965; Metopimazina [INN-Spanish]; Nortrip; Metopimazinum [INN-Latin];
  • CAS Registry Number:
  • Melting Point: 445.598
  • Flash Point: 390°C
  • Boiling Point: 721.2°Cat760mmHg
  • Density: 1.293g/cm3
  • Refractive index: 1.626
  • Safety Statements: Poison by intravenous, intraperitoneal, and subcutaneous routes. Moderately toxic by ingestion. An anti-emetic agent. When heated to decomposition it emits very toxic fumes of SOx and NOx.
  • Flash Point: 390°C
  • EINECS: 237-818-4
  • Molecular Weight: 445.59808
  • InchiKey: BQDBKDMTIJBJLA-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H27N3O3S2/c1-30(27,
    28)17-7-8-21-19(15-17)25(18-5-2-3-6-20(18)29-21)12-4-11-24-13-9-16(10-
    14-24)22(23)26/h2-3,5-8,15-16H,4,9-14H2,1H3,(H2,23,26)
  • Molecular Formula: C22H27N3O3S2
  • Molecular Structure:CAS No:14008-44-7 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide
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14008-44-7 Metopimazine

  • Metopimazine
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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14008-44-7 Metopimazine

  • Metopimazine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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14008-44-7 Metopimazine

  • Metopimazine, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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14008-44-7 METOPIMAZINE

  • Canada TLC PharmaChem., Inc. [Manufacturer]
  • Tel: 905-760-1098
  • Fax: 905-760-2098
  • Address: TLC PharmaChem., Inc.
    5-150 Connie Crescent
    Concord, Ontario
    L4K 1L9, Canada null,nullCanada
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14008-44-7 Metopimazine, 99%

  • Metopimazine, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,nullChina
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14008-44-7 Metopimazine

  • United States CBSCHEM LIMITED null
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 null,nullUnited States
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14008-44-7 Metopimazine

  • Metopimazine
  • India J.INC. [Manufacturer]
  • Tel: +91 79 30071152, 30071190, 30071175, 30071153
  • Fax: +91 79 30071176, 26574630
  • Address: # 95, Rangwala Towers, Law garden, Ellisbridge, Ahmedabad 380006, Gujarat State, India. 380006 AhmedabadINDIA Ahmedabad,nullIndia
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14008-44-7 4-Piperidinecarboxamide,1-[3-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]propyl]-

  • Denmark kemikalieimport [Manufacturers]
  • Tel: + 45 - 2034 3359
  • Fax: + 45 - 4542 3436
  • Address: Lyngby Hovedgade 61.2800 Lyngby. Lyngby,HovedgadeDenmark
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14008-44-7 METOPIMAZINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide
Title: Metopimazine
CAS Registry Number: 14008-44-7
CAS Name: 1-[3-[2-(Methylsulfonyl)-10H-phenothiazin-10-yl]propyl]-4-piperidinecarboxamide
Synonyms: 1-[3-[2-(methylsulfonyl)phenothiazin-10-yl]propyl]isonipecotamide; 10-[3-(4-carbamoylpiperidino)propyl]-2-(methanesulfonyl)phenothiazine; 1-[3-[2-(methylsulfonyl)phenothiazin-10-yl]propyl]-4-piperidinecarboxamide
Manufacturers' Codes: EXP-999; RP-9965
Trademarks: Vogalene (Thraplix)
Molecular Formula: C22H27N3O3S2
Molecular Weight: 445.60
Percent Composition: C 59.30%, H 6.11%, N 9.43%, O 10.77%, S 14.39%
Literature References: Prepn: Jacob, Robert, DE 1092476 (to Rh?ne-Poulenc), C.A. 56, 8723h (1962). Toxicity study: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: Solid, mp 170-171°. LD50 in male rats (mg/kg): 976 orally, 1080 s.c. (Goldenthal).
Melting point: mp 170-171°
Toxicity data: LD50 in male rats (mg/kg): 976 orally, 1080 s.c. (Goldenthal)
Therap-Cat: Antiemetic.
Keywords: Antiemetic.