Home > Name List By p > Pemetrexed disodium

CAS No 137281-23-3 , Pemetrexed disodium

  • Name: Pemetrexed disodium
  • Synonyms: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt; L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-; PEMETREXED; 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H pyrodo[2,3-d]Pyrimidin-5-yl)ethyl]-benzoic Acid; N-(4-[2-(2-Amino-4,7-Dihydro-4-oxo-1H-pyrrolo)[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-Gluamic Acid; PEFLOXACINMESYLATE PHARMA-0549;PEMETREXED ACID;Pemetrexed disodium; N-(4-(2-(2-Amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid;
  • CAS Registry Number:
  • Density: 1.59g/cm3
  • Refractive index: 1.723
  • Molecular Weight: 471.38
  • InChI: InChI=1/C20H21N5O6/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29)/t13-/m1/s1
  • Molecular Formula: C20H19N5Na2O6
  • Molecular Structure:CAS No:137281-23-3 Pemetrexed disodium

Related products

Search by region :

Select to

137281-23-3 Pemetrexed

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
Contact Supplier

137281-23-3 PEMETREXED-13C5

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
Contact Supplier

137281-23-3 N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid

Contact Supplier

137281-23-3 N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid

  • China Wuxi Mizat Chemical Technology Co., Ltd. [Manufacturer]
  • Tel: +86-510-86106900/ +86-510-86125752
  • Fax: +86-510-86125752
  • Address: No.205,zhencheng Road,
    HI-TECT District,
    Wuxi, Jiangsu,China null,nullChina
Contact Supplier

137281-23-3 Pemetrexed

  • Hong kong LEO CHEMICAL (HONG KONG) CO., LTD [Manufacturer]
  • Tel: 86-519-85098858/ 86-519-85098877
  • Fax: 86-519-85098888/8889
  • Address: Hong Kong Office :
    LEO CHEMICAL (HONG KONG) CO., LTD
    MNJ2070, RM1602,
    OMEGA PLAZA, 32 DUNDAS STREET,
    MONKOK, KL, HONG KONG null,nullHong kong
Contact Supplier

137281-23-3 N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid

Contact Supplier

137281-23-3 N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid

Contact Supplier

137281-23-3 N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid

  • China Beyond Pharmatech Corp, Ltd [Manufacturer, Agent]
  • Tel: +86-157-2497-1806
  • Fax: +86-571-5811-0575
  • Address: XiangYuan Road, GongShu District, Hangzhou, ZheJiang, 310011, China hangzhou,zhejiangChina
Contact Supplier

137281-23-3 N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid

  • China Originchem Co., Ltd. [Manufacturer]
  • Tel: 86-25-8697-8001/ 86-137-7051-9126 (mobile)
  • Fax: 86-25-8697-8002
  • Address: 101,Building 4, 8 HuaYuan Road,
    XuanWu District,
    NanJing P.R.China 210042 null,nullChina
Contact Supplier

137281-23-3 N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid

  • China Hangzhou Sida Organic Chemical Co., Ltd. [Manufacturers]
  • Tel: +86-571-88212350
  • Fax: +86-571-28050260
  • Address: Room 301, Building Auxiliary, Longdu Mansion,No.376.Tianmushan Road,Hangzhou 310012 China Hangzhou,ZhejiangChina
Contact Supplier

Select to

1/3
1 2 3 Next
References of Pemetrexed disodium
Title: Pemetrexed
CAS Registry Number: 137281-23-3
CAS Name: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid
Molecular Formula: C20H21N5O6
Molecular Weight: 427.41
Percent Composition: C 56.20%, H 4.95%, N 16.39%, O 22.46%
Literature References: Multitargeted antifolate; inhibits thymidylate synthase as well as other folate dependent enzymes. Prepn: E. C. Taylor et al., EP 432677; idem, US 5344932 (1991, 1994 both to Trustees Princeton Univ.); idem et al., J. Med. Chem. 35, 4450 (1992). Profile of enzyme inhibition: C. Shih et al., Adv. Enzyme Regul. 38, 135 (1998). HPLC determn in plasma: C. L. Hamilton, J. A. Kirkwood, J. Chromatogr. B 654, 297 (1994). Clinical pharmacokinetics in cancer patients: A. C. McDonald et al., Clin. Cancer Res. 4, 605 (1998). Clinical evaluation in colorectal carcinoma: W. John et al., Cancer 88, 1807 (2000); in pancreatic cancer: K. D. Miller et al., Ann. Oncol. 11, 101 (2000).
Properties: Crystals from 50% methanol/methylene chloride.
 
Derivative Type: Sodium salt
CAS Registry Number: 150399-23-8
Synonyms: Pemetrexed disodium
Manufacturers' Codes: LY-231514
Trademarks: Alimta (Lilly)
Molecular Formula: C20H19N5Na2O6
Molecular Weight: 471.37
Percent Composition: C 50.96%, H 4.06%, N 14.86%, Na 9.75%, O 20.37%
 
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Folic Acid Analogs/Antagonists.