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CAS No 13655-52-2 , 1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol Search by region : India

  • Name: 1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol
  • Synonyms: Aptine; Alprenololum [INN-Latin];1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol; Alprenolol [INN:BAN];Alfeprol; Alpheprol; Alprenololum; Yobir; Alfeprol [Russian];
  • CAS Registry Number:
  • Transport: 3249
  • Flash Point: 185.7°C
  • Boiling Point: 383.4°Cat760mmHg
  • Density: 1.007g/cm3
  • Safety Statements: A human poison by ingestion. Poison experimentally by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. See also ALLYL COMPOUNDS. A beta-adrenergic blocker.
  • Hazard Symbols: T: Toxic;
  • Flash Point: 185.7°C
  • EINECS: 237-140-9
  • Molecular Weight: 249.34862
  • InchiKey: PAZJSJFMUHDSTF-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-
    6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3
  • Risk Statements: 23/24/25-43
  • Molecular Formula: C15H23NO2
  • Molecular Structure:CAS No:13655-52-2 1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol

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References of 1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol
Title: Alprenolol
CAS Registry Number: 13655-52-2
CAS Name: 1-[(1-Methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-2-propanol
Synonyms: 1-(o-allylphenoxy)-3-(isopropylamino)-2-propanol
Manufacturers' Codes: H-56/28
Molecular Formula: C15H23NO2
Molecular Weight: 249.35
Percent Composition: C 72.25%, H 9.30%, N 5.62%, O 12.83%
Literature References: b-Adrenergic blocker. Prepn: Brandstrom et al., Acta Pharm. Suec. 3, 303 (1966); NL 6605692 (1966 to AB Hassle), C.A. 66, 46214p (1967); NL 6612958 (1967 to ICI), C.A. 67, 99851w (1967). Pharmacology: Marmo, Clin. Ter. 56, 121-176 (1971). Series of articles on clinical effect in myocardial infarction: Acta Med. Scand. 1984, Suppl. 680, 1-64.
 
Derivative Type: Hydrochloride
CAS Registry Number: 13707-88-5
Trademarks: Apllobal (Fujisawa); Aptine (Astra); Aptol Duriles (Astra); Gubernal (Novartis); Regletin (Teikoku Zoki); Yobir (Maruko)
Molecular Formula: C15H23NO2.HCl
Molecular Weight: 285.81
Percent Composition: C 63.04%, H 8.46%, N 4.90%, O 11.20%, Cl 12.40%
Properties: Crystals from ethyl acetate, mp 107-109°. LD50 in mice, rats, rabbits (mg/kg): 278.0, 597.0, 337.3 orally (Marmo).
Melting point: mp 107-109°
Toxicity data: LD50 in mice, rats, rabbits (mg/kg): 278.0, 597.0, 337.3 orally (Marmo)
 
Therap-Cat: Antihypertensive; antianginal; antiarrhythmic.
Keywords: ?Adrenergic Blocker; Antianginal; Antiarrhythmic; Antihypertensive; Aryloxypropanolamine Derivatives.