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CAS No 13422-51-0 , Hydroxocobalamin

  • Name: Hydroxocobalamin
  • Synonyms: Hydroxocobalamin;Vitamin B12b;
  • CAS Registry Number:
  • Melting Point: 200 deg C (decomposes)
  • Safety Statements: S26;S36;
  • Hazard Symbols: Xi
  • EINECS: 236-533-2
  • Molecular Weight: 1346.37
  • InChI: InChI=1S/C62H90N13O14P.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;1H2/q;+2;/p-2/t31-,34+,35+,36+,37-,41+,52+,53+,56?,57-,59+,60-,61-,62-;;/m0../s1
  • Risk Statements: 36/37/38
  • Molecular Formula: C62H89CoN13O15P
  • Molecular Structure:CAS No:13422-51-0 Hydroxocobalamin
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13422-51-0 HYDROXOCOBALAMIN ACETATE SALT

  • HYDROXOCOBALAMIN ACETATE SALT
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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13422-51-0 Vitamin B12

  • Vitamin B12
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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13422-51-0 LTS00950 HYDROXOCOBALAMIN(VITAMINB12)

  • Hong kong Lotus chemical (HK) Limited [Manufacturer]
  • Tel: +86 23 86092822 (China)/ +852 29738324 (Hong Kong)
  • Fax: +86 23 86092822
  • Address: Lotus Chemical Limited,. (China office)
    Address: 602 Room, 172#, Gaoyan Road, Yubei District, Chongqing, China
    Postcode: 401120 ,Hong kong
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13422-51-0 Hydroxocobalamin Acetate

  • Hydroxocobalamin Acetate
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,China
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13422-51-0 Cobinamide,Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with(5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3)

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13422-51-0 Hydroxocobalamin

  • India Triveni Chemicals []
  • Tel: +91-(260)-2400022, 3258683
  • Fax: +91-(260)-2400022/3264008
  • Address: 135, Pancharatna, Char Rasta, G.I.D.C., Vapi, Gujarat 396 195, ,India
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13422-51-0 Hydroxocobalamin

  • China Ningbo Inno Pharmchem Co., Ltd. [Manufacturers]
  • Tel: +86-(574)-87319282
  • Fax: +86-(574)-56877908
  • Address: 5F, Building 4, 1035 Guangxian Rd., Ningbo Hi-Tech Park, Ningbo, Zhejiang 315040, Ningbo,ZhejiangChina
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13422-51-0 Hydroxocobalamin

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13422-51-0 HYDROXOCOBALAMIN USP

  • United States Carbomer, Inc. [Manufacturer]
  • Tel: 858-552-0992/ (800) 239-7129
  • Fax: 858-552-0999
  • Address: PO Box 261026-1026
    San Diego, CA 92196 ,United States
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References of Hydroxocobalamin
Title: Hydroxocobalamin
CAS Registry Number: 13422-51-0
CAS Name: Cobinamide hydroxide dihydrogen phosphate (ester) inner salt 3¢-ester with 5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
Synonyms: a-(5,6-dimethylbenzimidazolyl)hydroxocobamide; vitamin B12a; hydroxocobemine; OHB12
Trademarks: Cobalin-H (Link); Dodécavit (Serb); Duradoce (Atlantis); Neo-Cytamen (Medeva); Redisol H (Merck & Co.)
Molecular Formula: C62H89CoN13O15P
Molecular Weight: 1346.36
Percent Composition: C 55.31%, H 6.66%, Co 4.38%, N 13.52%, O 17.83%, P 2.30%
Literature References: Physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aq soln as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide, q.q.v. Prepn: E. A. Kaczka et al., J. Am. Chem. Soc. 71, 1514 (1949); eidem, ibid. 73, 335 (1951); eidem, US 2738301 (1956 to Merck & Co.). Acids replace the hydroxo group with the anion of the acid: eidem, Science 112, 354 (1950). Prepn from cyanocobalamin: R. Bieganowski, G. Klar, Chem. Ztg. 106, 235 (1982). Clinical evaluation as antidote to cyanide: J. C. Forsyth et al., Clin. Toxicol. 31, 277 (1993). Review: "Vitamin B12" in Vitamins, W. Friedrich, Ed. (de Gruyter, Berlin, 1988) pp 837-928.
Properties: Dark red, orthorhombic needles or platelets from water + acetone. Darkens at 200°, but not melted at 300°. Absorption max (H2O): 279, 325, 359, 516, 537 nm (e 19000, 11400, 20600, 8900, 9500). Moderately sol in water and in the lower aliphatic alcohols. Practically insol in acetone, ether, petr ether, halogenated hydrocarbons, benzene.
Absorption maximum: Absorption max (H2O): 279, 325, 359, 516, 537 nm (e 19000, 11400, 20600, 8900, 9500)
 
Derivative Type: Aquacobalamin
CAS Registry Number: 13422-52-1
CAS Name: Cobinamide hydroxide monohydrate dihydrogen phosphate (ester) inner salt 3¢-ester with 5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
Synonyms: aquocobalamin; vitamin B12b; vitamin B12d
Molecular Formula: C62H90CoN13O15P.OH
Molecular Weight: 1364.37
Percent Composition: C 54.58%, H 6.72%, Co 4.32%, N 13.35%, O 18.76%, P 2.27%
Properties: Absorption max (H2O): 274, 317, 351, 499, 527 nm (e 20600, 6100, 26500, 8100, 8500).
Absorption maximum: Absorption max (H2O): 274, 317, 351, 499, 527 nm (e 20600, 6100, 26500, 8100, 8500)
 
Derivative Type: Acetatocobalamin
CAS Registry Number: 22465-48-1
Synonyms: Cobinamide acetate (salt) dihydrogen phosphate (ester) inner salt 3¢-ester with 5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
Trademarks: Depogamma (Woerwag); Docelan (Aventis); Novidroxin (Fatol)
Molecular Formula: C64H91CoN13O16P
Molecular Weight: 1388.39
Percent Composition: C 55.37%, H 6.61%, Co 4.24%, N 13.11%, O 18.44%, P 2.23%
Literature References: Prepn of stable solns: Marcus et al., FR 1336671 (1963 to Merck & Co.), C.A. 60, 380a (1964).
 
Derivative Type: Nitrocobalamin
CAS Registry Number: 20623-13-6
CAS Name: Cobinamide nitrite (salt) dihydrogen phosphate (ester) inner salt 3¢-ester with 5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
Synonyms: nitritocobalamin; vitamin B12c
Molecular Formula: C62H88CoN14O16P
Molecular Weight: 1375.35
Percent Composition: C 54.14%, H 6.45%, Co 4.28%, N 14.26%, O 18.61%, P 2.25%
Literature References: Prepn: E. A. Kaczka et al., J. Am. Chem. Soc. 73, 3569 (1951).
Properties: Red crystalline solid. Absorption max in water: 352, 527.5 nm (E1%1cm 153.2, 59.5); in 0.01N NaOH: 357, 535 nm (E1%1cm 139, 62.5).
Absorption maximum: Absorption max in water: 352, 527.5 nm (E1%1cm 153.2, 59.5); in 0.01N NaOH: 357, 535 nm (E1%1cm 139, 62.5)
 
Derivative Type: Sulfitocobalamin
CAS Registry Number: 15671-27-9
CAS Name: Cobinamide sulfite (1:1) (salt) dihydrogen phosphate (ester) inner salt 3¢-ester with 5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
Synonyms: cobalaminsulfonic acid
Molecular Formula: C62H89CoN13O17PS
Molecular Weight: 1410.42
Percent Composition: C 52.80%, H 6.36%, Co 4.18%, N 12.91%, O 19.28%, P 2.20%, S 2.27%
Literature References: Prepn: Fricke, US 2721162 (1955 to Abbott).
Properties: Absorption max: 275, 365, 418, 516 nm (E1%1cm 328, 130, 49, 61).
Absorption maximum: Absorption max: 275, 365, 418, 516 nm (E1%1cm 328, 130, 49, 61)
 
Therap-Cat: Vitamin (hematopoietic).
Therap-Cat-Vet: Vitamin (hematopoietic).
Keywords: Vitamin/Vitamin Source; Vitamin B12.