Home > Name List By s > Saquinavir

CAS No 127779-20-8 , Saquinavir

  • Name: Saquinavir
  • Synonyms: Saquinavir;N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-butanediamide;
  • CAS Registry Number:
  • Melting Point: 91.5 deg C
  • Density: 1.211 g/cm3
  • Refractive index: 1.598
  • Molecular Weight: 670.85
  • InChI: InChI=1/C38H50N6O5/c1-38(2,3)43-37(49)32-20-26-14-7-8-15-27(26)22-44(32)23-33(45)30(19-24-11-5-4-6-12-24)41-36(48)31(21-34(39)46)42-35(47)29-18-17-25-13-9-10-16-28(25)40-29/h4-6,9-13,16-18,26-27,30-33,45H,7-8,14-15,19-23H2,1-3H3,(H2,39,46)(H,41,48)(H,42,47)(H,43,49)/t26?,27?,30-,31-,32-,33+/m0/s1
  • Molecular Formula: C38H50N6O5
  • Molecular Structure:CAS No:127779-20-8 Saquinavir

Related products

Search by region :

Select to

127779-20-8 Saquinavir

  • An HIV protease inhibitor. It is often used in combination with ritonavir or lopinavir/ritonavir for HIV/AIDS infection therapy.https://www.bocsci.com/saquinavir-cas-127779-20-8-item-84-82825.html
  • Min. Order: 10
  • United States BOC Sciences [Manufacturer]
  • Tel: 1-631-4854226
  • Fax: 1-631-6147828
  • Address: Ramsey Road Shirley,New YorkUnited States
Contact Supplier

127779-20-8 SAQUINAVIR

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
Contact Supplier

127779-20-8 Saquinavir

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
Contact Supplier

127779-20-8 SAQUINAVIR

  • United States EJY Tech, Inc. [Manufacturer]
  • Tel: 301-526-7059
  • Fax: 301-561-6521
  • Address: 9430 Key West Avenue
    Suite 220
    Rockville , MD 20850 null,nullUnited States
Contact Supplier

127779-20-8 SAQUINAVIR

  • Canada Synth?se AptoChem Inc. [Manufacturer]
  • Tel: 514-496-4252
  • Fax: 514-496-4253
  • Address: Synth?se AptoChem Inc.
    6100 Royalmount Ave
    Montreal, QC
    Canada
    H4P 2R2 null,nullCanada
Contact Supplier

127779-20-8 aquinavir

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China null,ZheJiangChina
Contact Supplier

127779-20-8 SAQUINAVIR

  • China Taizhou Creating Chemical Co.,Ltd [Manufacturer]
  • Tel: +86-576-88827176/ +86-576-88820069
  • Fax: +86-576-88822496
  • Address: B Suite 12F,
    Jiangbin Building,Jiaojiang,Taizhou,
    Zhejiang China null,nullChina
Contact Supplier

127779-20-8 Saquinavir Mesylate

Contact Supplier

127779-20-8 Saquinavir

  • United States Louston International null
  • Tel: +1-610-85909860
  • Fax: +1-610-8599861
  • Address: 168 East Ridge Road, Industrial Center, # 202, Linwood, PA 19061.USA null,nullUnited States
Contact Supplier

127779-20-8 aquinavir

  • China Shanghai Hao Su Chem-Tech lnc. [Manufacturers]
  • Tel: 021-6661 0036 021-5653 8833
  • Fax: (86 21) 5653 3269
  • Address: 201-204,2 BLDG,1009 North Zhong Shan Road, Shanghai Shanghai,ShanghaiChina
Contact Supplier

Select to

References of Saquinavir
Title: Saquinavir
CAS Registry Number: 127779-20-8
CAS Name: (2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide
Synonyms: (S)-N-[(aS)-a-[(1R)-2-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydro-2(1H)-isoquinolyl]-1-hydroxyethyl]phenethyl]-2-quinaldamido succinamide; N-tert-butyldecahydro-2-[2(R)-hydroxy-4-phenyl-3(S)-[[N-(2-quinolylcarbonyl)-L-asparaginyl]amino]butyl](4aS,8aS)-isoquinoline-3(S)-carboxamide
Manufacturers' Codes: Ro-31-8959
Molecular Formula: C38H50N6O5
Molecular Weight: 670.84
Percent Composition: C 68.04%, H 7.51%, N 12.53%, O 11.92%
Literature References: Selective HIV protease inhibitor. Prepn: J. A. Martin, S. Redshaw, EP 432695; eidem, US 5196438 (1991, 1993 both to Hoffmann-LaRoche); K. E. B. Parkes et al., J. Org. Chem. 59, 3656 (1994). In vitro HIV proteinase inhibition: N. A. Roberts et al., Science 248, 358 (1990). Antiviral properties: J. C. Craig et al., Antiviral Res. 16, 295 (1991); S. Galpin et al., Antiviral Chem. Chemother. 5, 43-45 (1994). Clinical evaluation of tolerability and activity: V. S. Kitchen et al., Lancet 345, 952 (1995). Review of pharmacology and clinical experience: S. Kravcik, Expert Opin. Pharmacother. 2 303-315 (2001).
Properties: White crystalline solid. [a]D20 -55.9° (c = 0.5 in methanol). Soly (21°): 0.22 g/100 ml water.
Optical Rotation: [a]D20 -55.9° (c = 0.5 in methanol)
 
Derivative Type: Methanesulfonate salt
CAS Registry Number: 149845-06-7
Synonyms: Saquinavir mesylate
Manufacturers' Codes: Ro-31-8959/003
Trademarks: Fortovase (Roche); Invirase (Roche)
Molecular Formula: C38H50N6O5.CH3SO3H
Molecular Weight: 766.95
Percent Composition: C 61.08%, H 7.10%, N 10.96%, O 16.69%, S 4.18%
 
Therap-Cat: Antiviral.
Keywords: Antiviral; Peptidomimetics; HIV Protease Inhibitor.