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CAS No 123-78-4 , (E,2S,3R)-2-aminooctadec-4-ene-1,3-diol

  • Name: (E,2S,3R)-2-aminooctadec-4-ene-1,3-diol
  • Synonyms: cerebroside; Sphingenine;4-Sphingenine; Sphing-4-enine; D-Sphingosine; Sphingoid;(E,2S,3R)-2-aminooctadec-4-ene-1,3-diol; D-erythro-Sphingosine;
  • CAS Registry Number:
  • Transport: OTH
  • Melting Point: 81 - 82
  • Flash Point: 445.9°Cat760mmHg
  • Boiling Point: 445.9°Cat760mmHg
  • Density: 0.939g/cm3
  • Refractive index: 1.489
  • Safety Statements: S22-24/25
  • Hazard Symbols: Not regulated UN NO.
  • Flash Point: 445.9°Cat760mmHg
  • EINECS: 204-651-3
  • Molecular Weight: 299.49188
  • InchiKey: WWUZIQQURGPMPG-KRWOKUGFSA-N
  • InChI: InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-
    20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1
  • Molecular Formula: C18H37NO2
  • Molecular Structure:CAS No:123-78-4 (E,2S,3R)-2-aminooctadec-4-ene-1,3-diol
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123-78-4 D -ERYTHRO -SPHINGOSINE

  • D -ERYTHRO -SPHINGOSINE
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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123-78-4 D-erythro-Sphingosine

  • D-erythro-Sphingosine
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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123-78-4 D-ERYTHRO-SPHINGOSINE C-18

  • United States Cayman Chemical Company [Manufacturer]
  • Tel: 734-975-3939; 734-975-3897 (Sales)/ 800-364-9897 (Customer Service)
  • Address: 1180 E.Ellsworth Rd.
    Ann Arbor, MI 48197
    800-364-9897 null,nullUnited States
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123-78-4 D-erythro-Sphingosine (synthetic)

  • D-erythro-Sphingosine (synthetic), > 98%
  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland null,nullSwitzerland
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123-78-4 D-Sphingosine (from bovine brain sphinogomyelin)

  • D-Sphingosine (from bovine brain sphinogomyelin)
  • United States Chem-Impex International, Inc. [Manufacturer]
  • Tel: 630 766 2112
  • Fax: 630 766 2218
  • Address: 935 Dillon Drive Wood Dale IL 60191 USA ,nullUnited States
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123-78-4 D-ERYTHRO-SPHINGOSINE (SYNTHETIC)

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany null,nullGermany
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123-78-4 D-SPHINGOSINE; TRANS-D-ERYTHRO-2-AMINO-4-OCTADECENE-1,3-DIOL

  • United States CNH Technologies, Inc. [Manufacturer]
  • Tel: 781-933-0362
  • Fax: 781-933-1839
  • Address: CNH Technologies, Inc.
    10A Henshaw Street
    Woburn, MA 01801 null,nullUnited States
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123-78-4 trans-D-erythro-2-Amino-4-octadecene-1,3-diol

  • trans-D-erythro-2-Amino-4-octadecene-1,3-diolD-erythro-Sphingosine (synthetic)
  • United Kingdom Tocris Bioscience [Manufacturer]
  • Tel: + 44 (0)117 916 3333
  • Fax: + 44 (0)117 916 3344
  • Address: Tocris Bioscience Tocris House Hung Road BS11 9XJ BristolUNITED KINGDOM BS11 9XJ Bristol,nullUnited Kingdom
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123-78-4 D-Sphingosine

  • D-Sphingosine
  • United States LKT Laboratories, Inc [Manufacturer]
  • Tel: (888)-558-5227
  • Fax:
  • Address: 2233 University Ave. West 55114-1600 St. PaulUNITED STATES 55114-1600 St. Paul,nullUnited States
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123-78-4 4-Octadecene-1,3-diol,2-amino-, (2S,3R,4E)-

  • United States LKT Laboratories Inc. null
  • Tel: +1 888-558-5227
  • Fax: +1-(651)-644-8424
  • Address: Toll free 888-LKT-LABS St. Paul,nullUnited States
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References of (E,2S,3R)-2-aminooctadec-4-ene-1,3-diol
Title: Sphingosine
CAS Registry Number: 123-78-4
CAS Name: (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol
Synonyms: (E)-D-erythro-4-octadecene-1,3-diol; 1,3-dihydroxy-2-amino-4-octadecene; 4-sphingenine
Molecular Formula: C18H37NO2
Molecular Weight: 299.49
Percent Composition: C 72.19%, H 12.45%, N 4.68%, O 10.68%
Literature References: Important membrane component; long-chain amino-dialcohol; moiety of certain phosphatides, such as sphingomyelins, cerebrosides, and gangliosides. Natural sphingosine is D-(+)-erythro-1,3-dihydroxy-2-amino-4-trans-octadecene. Does not exist in the free state in animals, plants or microorganisms. First obtained by hydrolysis of cerebrosides from brains: J. L. W. Thudichum, Die Konstitution des Gehirns des Menschen und der Tiere (Tübingen, 1901). Separation procedures: Carter et al., J. Biol. Chem. 170, 269 (1947); Wittenberg, ibid. 216, 379 (1955); Tipton, Biochem. Prep. 9, 127 (1962). Stereospecific synthesis of DL-erythro-trans-form and isomers: C. A. Grob, F. Gadient, Helv. Chim. Acta 40, 1145 (1957). Stereoselective synthesis: H. Newman, J. Am. Chem. Soc. 95, 4098 (1973); B. Bernet, A. Vasella, Tetrahedron Lett. 24, 5491 (1983). Comprehensive review: C. A. Grob, Record Chem. Progr. (Kresge-Hooker Sci. Lib.) 18, 55-66 (1957); D. Shapiro, Chemistry of Sphingolipids (Hermann, Paris, 1969) 111 pp. Bibliography: Rodd's Chemistry of Carbon Compounds Vol. I, part E, S. Coffey, Ed. (Elsevier, New York, 2nd ed., 1976) pp 394-397.
 
Derivative Type: DL-Sphingosine
Properties: Waxy crystals from ether + pentane, mp 67°.
Melting point: mp 67°
 
Derivative Type: DL-Triacetylsphingosine
Molecular Formula: C24H43NO5
Molecular Weight: 425.60
Percent Composition: C 67.73%, H 10.18%, N 3.29%, O 18.80%
Properties: Crystals from pentane + ether, mp 91-92°.
Melting point: mp 91-92°
 
Derivative Type: Triacetyl derivative of natural sphingosine
Molecular Formula: C24H43NO5
Molecular Weight: 425.60
Percent Composition: C 67.73%, H 10.18%, N 3.29%, O 18.80%
Properties: Crystals, mp 101-102°. [a]D25 -11.7° (chloroform).
Melting point: mp 101-102°
Optical Rotation: [a]D25 -11.7° (chloroform)