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CAS No 122841-10-5 , Cefoselis

  • Name: Cefoselis
  • Synonyms: (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[2-(2-hydroxyethyl)-3-iminopyrazol-1-yl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Cefoselis;Cefoselis main-ring;
  • CAS Registry Number:
  • Flash Point: °Cat760mmHg
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Flash Point: °Cat760mmHg
  • Molecular Weight: 522.56
  • InChI: InChI=1/C19H22N8O6S2/c1-33-24-12(10-8-35-19(21)22-10)15(29)23-13-16(30)27-14(18(31)32)9(7-34-17(13)27)6-25-3-2-11(20)26(25)4-5-28/h2-3,8,13,17,20,28H,4-7H2,1H3,(H4,21,22,23,29,31,32)/b24-12+/t13-,17-/m1/s1
  • Molecular Formula: C19H22N8O6S2
  • Molecular Structure:CAS No:122841-10-5 Cefoselis

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  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
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References of Cefoselis
Title: Cefoselis
CAS Registry Number: 122841-10-5
CAS Name: (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms: (syn)-7b-[2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-[3-amino-2-(2-hydroxyethyl)-1-pyrazolio]methyl-3-cephem-4-carboxylate; (-)-5-amino-2-[[(6R,7R)-7-[2-(2-amino-4-thiazolyl)glyoxylamido]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-(2-hydroxyethyl)pyrazolium hydroxide inner salt 72-(Z)-(O-methyloxime)
Molecular Formula: C19H22N8O6S2
Molecular Weight: 522.56
Percent Composition: C 43.67%, H 4.24%, N 21.44%, O 18.37%, S 12.27%
Literature References: Fourth generation cephalosporin antibiotic. Prepn: K. Sakane et al., EP 307804; eidem, US 4952578 (1989, 1990 both to Fujisawa); H. Ohki et al., J. Antibiot. 46, 359 (1993). In vitro activity and b-lactamase stability: H. C. Neu et al., Antimicrob. Agents Chemother. 37, 566 (1993). Clinical pharmacokinetics: R. Wise et al., ibid. 38, 2369 (1994). Series of articles on activity, clinical pharmacology and therapeutic efficacy: Chemotherapy (Tokyo) 42, Suppl. 3, 1-464 (1994).
 
Derivative Type: Sulfate
CAS Registry Number: 122841-12-7
Manufacturers' Codes: FK-037
Trademarks: Wincef (Fujisawa)
Molecular Formula: C19H22N8O6S2.H2SO4
Molecular Weight: 620.64
Percent Composition: C 36.77%, H 3.90%, N 18.05%, O 25.78%, S 15.50%
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Cephalosporins.