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CAS No 12192-57-3 , Gold, [1-(thio-kS)-D-glucopyranosato-kO2]-

  • Name: Gold, [1-(thio-kS)-D-glucopyranosato-kO2]-
  • Synonyms: Gold, (1-thio-D-glucopyranosato)- (8CI);(D-Glucopyranosylthio)gold; Goldthioglucose; Gold, (D-glucopyranosylthio)-; Aureotan; Solganal B;Gold, [1-(thio-kS)-D-glucopyranosato-kO2]-; Glucose, 1-thio-, gold salt (1:1); Gold,(1-thio-D-glucopyranosato-O2,S1)-;Authron; Auromyose; Solganal; D-Glucopyranose, 1-thio-, gold complex; Aurumine; Aurothioglucose; Oronol;D-Glucose,1-thio-, S-gold deriv. (6CI); Glysanol B; Brenol;
  • CAS Registry Number:
  • Transport: 2811
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Safety Statements: Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. A deadly human poison by an unspecified route. An experimental poison by intramuscular route. Moderately toxic by subcutaneous and intravenous routes. Human systemic effects: nausea or vomiting, cholestatic jaundice, and eye effects. An experimental teratogen. Other experimental reproductive effects. See also GOLD COMPOUNDS. When heated to decomposition it emits very toxic fumes of SOx. Used to treat rheumatoid arthritis.
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: °C
  • EINECS: 235-365-7
  • Molecular Weight: 392.20
  • InChI: InChI=1/C6H12O5S.Au/c7-1-2-3(8)4(9)5(10)6(12)11-2;/h2-10,12H,1H2;/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1/rC6H11AuO5S/c7-13-6-5(11)4(10)3(9)2(1-8)12-6/h2-6,8-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
  • Risk Statements: 42/43
  • Molecular Formula: C6H11 Au O5 S
  • Molecular Structure:CAS No:12192-57-3 Gold, [1-(thio-kS)-D-glucopyranosato-kO2]-

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References of Gold, [1-(thio-kS)-D-glucopyranosato-kO2]-
Title: Aurothioglucose
CAS Registry Number: 12192-57-3
CAS Name: (1-Thio-D-glucopyranosato-O2,S1)gold
Synonyms: (1-D-glucosylthio)gold; gold thioglucose
Trademarks: Aureotan (Byk Gulden); Solganal (Schering)
Molecular Formula: C6H11AuO5S
Molecular Weight: 392.18
Percent Composition: C 18.38%, H 2.83%, Au 50.22%, O 20.40%, S 8.18%
Literature References: Disease modifying antirheumatic drug (DMARD). Prepn: Lebeau-Janot, Traité Pharm. Chim. II, 661 (1956). Induction of obesity in exptl animals: A. F. Debons et al., Fed. Proc. 36, 143 (1977). Clinical comparison with auranofin, q.v., in rheumatoid arthritis: P. L. C. M. Van Riel et al., Clin. Rheumatol. 5, 359 (1986); P. E. Prete et al., Clin. Rheumatol. 13, 60 (1994).
Properties: Yellow crystals. Slight mercaptan-like odor. Sol in water with decompn; slightly sol in propylene glycol. Practically insol in acetone, alcohol, chloroform, ether.
Use: To produce obesity in exptl animals.
Therap-Cat: Antirheumatic.
Keywords: Antiarthritic/Antirheumatic.