Home > Name List By 2 > 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

CAS No 120014-06-4 , 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

  • Name: 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
  • Synonyms: Donepezil [INN:BAN]; 120014-06-4; Donaz (TN); Spectrum_001664; Aricept ODT; CHEBI:53289;Eranz;2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one; Donepezil (INN);
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 207 ºC
  • Flash Point: 273.1ºC
  • Boiling Point: 527.9ºCat760mmHg
  • Density: 1.141g/cm3
  • Refractive index: 1.578
  • Water Solubility: 2.931 MG/L
  • Safety Statements: 26-36
  • Hazard Symbols: Xi: Irritant;
  • Flash Point: 273.1ºC
  • Molecular Weight: 379.49196
  • InchiKey: ADEBPBSSDYVVLD-UHFFFAOYSA-N
  • InChI: InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-
    8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3
  • Risk Statements: 36/37/38
  • Molecular Formula: C24H29NO3
  • Molecular Structure:CAS No:120014-06-4 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
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120014-06-4 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

  • 99% Donepezil powder for Alzheimer's disease Donepezil Molecular Formula:C24H29NO3 Donepezil Formula Weight:379.49 Donepezil CAS No.:120014-06-4 Donepezil Purity:99% Donepezil Appearance:white powder
  • China Wuhan Yuancheng Technology Development Co., Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-188-72220796
  • Address: No.496 Zhongshan Road, Wuchang District, Wuhan wuhan,HubeiChina
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120014-06-4 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

  • 99% Donepezil Powder for Alzheimer′s Disease 99% Donepezil Powder for Alzheimer′s Disease CAS 120014-06-4 99% Donepezil powder for Alzheimer's disease Donepezil Molecular Formula:C24H29NO3 Donepezil Formula Weight:379.49 Donepezil CAS No.:120014-06...
  • China Hubei Yuancheng Hezhong Technology Co.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-188-72220796
  • Address: No.496 wuhan,HubeiChina
Contact Supplier

120014-06-4 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

  • 99% Donepezil powder for Alzheimer's disease Donepezil Molecular Formula:C24H29NO3 Donepezil Formula Weight:379.49 Donepezil CAS No.:120014-06-4 Donepezil Purity:99% Donepezil Appearance:white powder
  • China WuHan YuanCheng FeiChuang Technology Co.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-188-72220796
  • Address: No.496 wuhan,HubeiChina
Contact Supplier

120014-06-4 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

  • Donepezil CAS No.:120014-06-4 Donepezil Purity:99% Donepezil Appearance:white powder
  • China WuHan YuanCheng GongChuang Technology Co.,Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-188-72220796
  • Address: No.496 wuhan,HubeiChina
Contact Supplier

120014-06-4 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

  • Donepezil CAS No.:120014-06-4 Donepezil Purity:99% Donepezil Appearance:white powder
  • China Hubei Yuancheng Saichuang Technology Co,Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-188-72220799
  • Address: No.496 ZhongShan Road, Wuchang District, Wuhan,Hubei wuhan,HubeiChina
Contact Supplier

120014-06-4 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

  • Donepezil CAS No.:120014-06-4 Donepezil Purity:99% Donepezil Appearance:white powder
  • China Hubei Yuancheng Saisi Technology Co., Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-188-72220796
  • Address: No.496,Wuchang Distreet wuhan,HubeiChina
Contact Supplier

120014-06-4 DONEPEZIL

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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120014-06-4 Donepezil

  • Donepezil
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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120014-06-4 Donepezil

  • IUPAC NAME-(RS)-2-[(1-benzyl-4-piperidyl)methyl]- 5,6-dimethoxy-2,3-dihydroinden-1-one MOLECULAR FORMULA-C24H29NO3 MOLAR MASS-379.492 g/mol
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Harsool Aurangabad,MaharashtraIndia

120014-06-4 donepezil

  • IUPAC NAME-(RS)-2-[(1-benzyl-4-piperidyl)methyl]- 5,6-dimethoxy-2,3-dihydroinden-1-one MOLECULAR FORMULA-C24H29NO3 MOLAR MASS-379.492 g/mol Donepezil, marketed under the trade name Aricept by its developer Eisai and partner Pfizer, and also marketed ...
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641875
  • Address: Harsool Aurangabad,MaharashtraIndia

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References of 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
Title: Donepezil
CAS Registry Number: 120014-06-4
CAS Name: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one
Synonyms: 5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-2,3-dihydro-1H-inden-1-one; 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine
Molecular Formula: C24H29NO3
Molecular Weight: 379.49
Percent Composition: C 75.96%, H 7.70%, N 3.69%, O 12.65%
Literature References: Acetylcholinesterase inhibitor. Prepn: H. Sugimoto et al., EP 296560, eidem, US 4895841 (1988, 1990 both to Eisai). Synthesis: Y. Iimura et al., J. Labelled Compd. Radiopharm. 27, 835 (1989). Resolution of enantiomers: J. Haginaka, C. Seyama, J. Chromatogr. B 577, 95 (1992). Clinical pharmacokinetics: A. Ohnishi et al., J. Clin. Pharmacol. 33, 1086 (1993). Clinical trials in Alzheimer's disease: R. C. Mohs et al., Neurology 57, 481 (2001); B. Winblad et al., ibid. 489. Review of pharmacology and clinical experience in cognitive disorders: G. C. Román, S. J. Rogers, Expert Opin. Pharmacother. 5, 161-180 (2004).
 
Derivative Type: Hydrochloride
CAS Registry Number: 120011-70-3
Manufacturers' Codes: E-2020
Trademarks: Aricept (Eisai)
Molecular Formula: C24H29NO3.HCl
Molecular Weight: 415.95
Percent Composition: C 69.30%, H 7.27%, N 3.37%, O 11.54%, Cl 8.52%
Properties: Crystals from methanol/IPE, mp 211-212° (dec).
Melting point: mp 211-212° (dec)
 
Therap-Cat: Nootropic.
Keywords: Nootropic.