Home > Name List By 4 > 4-oxo-4-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]butanoic acid

CAS No 116-43-8 , 4-oxo-4-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]butanoic acid

  • Name: 4-oxo-4-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]butanoic acid
  • Synonyms: 116-43-8;4-oxo-4-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]butanoic acid; Sulfasuccinil; Sulfadigesin; 4'-(2-Thiazolylsulfamoyl)succinanilic acid; Cremosuxidine; Sulfasuccidine; Colistatin; Kaoxidin;
  • CAS Registry Number:
  • Transport: 3249
  • Melting Point: 187 - 193
  • Density: 1.601g/cm3
  • Refractive index: 1.679
  • Safety Statements: R42/43
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 204-141-0
  • Molecular Weight: 355.38942
  • InchiKey: SKVLYVHULOWXTD-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,
    21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)
  • Risk Statements: S22;S36/37;S45
  • Molecular Formula: C13H13N3O5S2
  • Molecular Structure:CAS No:116-43-8 4-oxo-4-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]butanoic acid

Related products

Search by region :

Select to

116-43-8 SUCCINYLSULFATHIAZOLE

  • United States City Chemical LLC [Manufacturer]
  • Tel: (800)-248-2436/ 203-932-2489
  • Fax: 203 937-8400
  • Address: 139 Allings Crossing Road
    West Haven, CT 06516 null,nullUnited States
Contact Supplier

116-43-8 SUCCINYLSULFATHIAZOLE

  • United States Advance Scientific & Chemical, Inc. [Manufacturer]
  • Tel: (954) 327-0900
  • Fax: (954) 327-0903
  • Address: Advance Scientific & Chemical, Inc.
    2345 SW 34th Street
    Fort Lauderdale, FL 33312 null,nullUnited States
Contact Supplier

116-43-8 AOKCHEM40020 SUCCINYLSULFATHIAZOLE

  • China AOKchem Group Limited [Manufacturer]
  • Tel: +86-21-68712331
  • Fax: +86-21-68712362
  • Address: Shanghai AOKChem Group Limited
    Room 4-302, No. 1768 Boxing Rd.,
    Shanghai, China null,nullChina
Contact Supplier

116-43-8 4-(Succinylamino)-N-(2-Thiazolyl)Benzenesulfonamide

  • SCFC-Sourcing Chemicals From China is the best vender for this materials Name:4-(Succinylamino)-N-(2-Thiazolyl)Benzenesulfonamide CAS:116-43-8
  • China Sourcing Chemicals Inc. [Manufacturer]
  • Tel: 86-13385832632
  • Fax: 86-0573-82222646
  • Address: No.1000 South Lake District, Jiaxing City, Zhejiang Province Jiaxing,nullChina
Contact Supplier

116-43-8 SUCCINYLSULFATHIAZOLE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of 4-oxo-4-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]butanoic acid
Title: Succinylsulfathiazole
CAS Registry Number: 116-43-8
CAS Name: 4-Oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]butanoic acid
Synonyms: 4￠-(2-thiazolylsulfamoyl)succinanilic acid; p-2-thiazolylsulfamylsuccinanilic acid; 2-(N4-succinylsulfanilamido)thiazole
Trademarks: Sulfasuxidine (Merck & Co.)
Molecular Formula: C13H13N3O5S2
Molecular Weight: 355.39
Percent Composition: C 43.93%, H 3.69%, N 11.82%, O 22.51%, S 18.04%
Literature References: Prepd by refluxing sulfathiazole with a slight excess of succinic anhydride in alcohol: Moore, Miller, J. Am. Chem. Soc. 64, 1572 (1942); US 2324013; US 2324014 (both 1943); by refluxing p-succinimidobenzenesulfonyl chloride with 2-aminothiazole in benzene: GB 578004 (1946). Toxicology: A. D. Welch et al., J. Pharmacol. Exp. Ther. 75, 231 (1942).
 
Derivative Type: Monohydrate
Properties: Crystals with unclear mp. Has been reported as mp 184-186°; also reported as mp 192-195°. Emits pungent fumes on heating to mp. One gram dissolves in about 4800 ml water. Soluble in solns of alkali hydroxides and in solns of sodium bicarbonate with the evolution of carbon dioxide; sparingly sol in alcohol and in acetone. Insol in chloroform and ether. LD50 i.p. in mice: ~5.7 g/kg (Welch).
Melting point: mp 184-186°; mp 192-195°
Toxicity data: LD50 i.p. in mice: ~5.7 g/kg (Welch)
 
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial, esp in enteric infections.
Keywords: Antibacterial (Synthetic); Sulfonamides.