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CAS No 116-38-1 , ethyl-(3-hydroxyphenyl)-dimethylazanium

  • Name: ethyl-(3-hydroxyphenyl)-dimethylazanium
  • Synonyms: Antirex; 116-38-1;chloride;ethyl-(3-hydroxyphenyl)-dimethylazanium; Cloruro de edrofonio; Edrophonii chloridum; Enlon; Tensilon chloride;Edrophonium chloride; Ethyl(m-hydroxyphenyl)dimethylammonium chloride;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Water Solubility: Soluble in water (50mg/ml)
  • Safety Statements: Poison by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of Cl−, NH3, and NOx. See also CHLORIDES.
  • Flash Point: °C
  • EINECS: 204-138-4
  • Molecular Weight: 201.69314
  • InchiKey: BXKDSDJJOVIHMX-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H15NO.ClH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H
  • Molecular Formula: C10H16ClNO
  • Molecular Structure:CAS No:116-38-1 ethyl-(3-hydroxyphenyl)-dimethylazanium

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References of ethyl-(3-hydroxyphenyl)-dimethylazanium
Title: Edrophonium Chloride
CAS Registry Number: 116-38-1
CAS Name: N-Ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride
Synonyms: ethyl(m-hydroxyphenyl)dimethylammonium chloride; (3-hydroxyphenyl)dimethylethylammonium chloride; 3-hydroxy-N,N-dimethyl-N-ethylanilinium chloride
Trademarks: Antirex (Kyorin); Enlon (Ohmeda); Reversol (Organon); Tensilon (Valeant)
Molecular Formula: C10H16ClNO
Molecular Weight: 201.69
Percent Composition: C 59.55%, H 8.00%, Cl 17.58%, N 6.94%, O 7.93%
Literature References: Cholinesterase inhibitor. Prepn: J. A. Aeschlimann, A. Stempel, US 2647924 (1953 to Hoffmann-La Roche). LC determn in biological fluids: M. G. M. DeRuyter et al., J. Chromatogr. 183, 193 (1980). Clinical evaluation in reversal of neuromuscular blockade: D. M. Fisher et al., Anesthesiology 61, 428 (1984). Clinical study in supraventricular tachycardia: J. D. Cantwell et al., Arch. Int. Med. 130, 221 (1972). Diagnostic use in myasthenia gravis: I. M. Williams et al., Clin. Exp. Neurol. 22, 1 (1986); in esophageal chest pain: C. A. Lee et al., Dig. Dis. Sci. 32, 682 (1987).
Properties: Crystals from isopropanol, dec 162-163°. pH of 1% aq soln 4-5. Very sol in water; freely sol in alcohol. Insol in chloroform, ether.
 
Derivative Type: Edrophonium Bromide
Synonyms: Edrophone bromide
Manufacturers' Codes: Ro-2-3198
Molecular Formula: C10H16BrNO
Molecular Weight: 246.14
Percent Composition: C 48.80%, H 6.55%, Br 32.46%, N 5.69%, O 6.50%
Properties: Crystals from ethanol + ether, dec 151-152°. Bitter taste. Sol in water (more than 10%). Moderately sol in alcohol. Practically insol in ether. Solns are stable.
 
Therap-Cat: Cholinergic; antidote to curare; diagnostic aid (myasthenia gravis).
Keywords: Antidote (Curare); Cholinergic; Diagnostic Aid.