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CAS No 1083-57-4 , N-(4-ethoxyphenyl)-3-hydroxybutanamide

  • Name: N-(4-ethoxyphenyl)-3-hydroxybutanamide
  • Synonyms: N-(4-Ethoxyphenyl)-3-hydroxybutanamide; Betadid;3-Hydroxy-p-butyrophenetidide;N-(4-ethoxyphenyl)-3-hydroxybutanamide; 1083-57-4; 4'-Ethoxy-3-hydroxybutyranilide;
  • CAS Registry Number:
  • Melting Point: 160 °C
  • Flash Point: 216°C
  • Boiling Point: 433.5°C at 760 mmHg
  • Density: 1.151g/cm3
  • Refractive index: 1.558
  • Safety Statements: Moderately toxic by ingestion and intraperitoneal routes. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
  • Hazard Symbols: T
  • Flash Point: 216°C
  • EINECS: 214-109-8
  • Molecular Weight: 223.26828
  • InchiKey: LIAWQASKBFCRNR-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H17NO3/c1-3-16-11-6-4-10(5-7-11)13-12(15)8-9(2)14/h4-7,9,
    14H,3,8H2,1-2H3,(H,13,15)
  • Risk Statements: 45-46-20/21/22
  • Molecular Formula: C12H17NO3
  • Molecular Structure:CAS No:1083-57-4 N-(4-ethoxyphenyl)-3-hydroxybutanamide
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1083-57-4 3-Hydroxy-p-butyrophenetidine;0.99

  • 3-Hydroxy-p-butyrophenetidine;0.99
  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
  • Fax: +49 721 95061-80
  • Address: Im Schlehert 10
    76187 Karlsruhe
    Germany null,nullGermany
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1083-57-4 3-HYDROXY-P-BUTYROPHENETIDINE

  • 3-HYDROXY-P-BUTYROPHENETIDINE
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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1083-57-4 3-Hydroxy-p-butyrophenetidine

  • 3-Hydroxy-p-butyrophenetidine
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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1083-57-4 Bucetin

  • Bucetin, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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1083-57-4 Bucetin

  • Bucetin, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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1083-57-4 BUCETIN

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of N-(4-ethoxyphenyl)-3-hydroxybutanamide
Title: Bucetin
CAS Registry Number: 1083-57-4
CAS Name: N-(4-Ethoxyphenyl)-3-hydroxybutanamide
Synonyms: 3-hydroxy-p-butyrophenetidide; b-hydroxybutyric acid p-phenetidide; p-ethoxy-N-(b-hydroxybutyryl)aniline
Trademarks: Betadid
Molecular Formula: C12H17NO3
Molecular Weight: 223.27
Percent Composition: C 64.55%, H 7.67%, N 6.27%, O 21.50%
Literature References: Phenetidine derivative with analgesic and antipyretic activity. Prepn: G. Ehrhart et al., US 2830087 (1958 to Hoechst); and pharmacology: eidem, Arzneim.-Forsch. 15, 727 (1965). Toxicity data: H. Fujimura, Folia Pharmacol. Jpn. 62, 123 (1966). Metabolism in rabbits: J. Shibasaki et al., Chem. Pharm. Bull. 16, 1726, 2269 (1968). Synergistic effect with ethenzamide, q.v.: H. Kojima et al., Oyo Yakuri 16, 549 (1978), C.A. 90, 81035y (1979). TLC determn in saliva: P. Rohdewald, G. Drehsen, J. Chromatogr. 225, 427 (1981).
Properties: Crystals from isopropanol, mp 160°. Sparingly sol in water. LD50 in mice (mg/kg): 790 i.p., 2800 orally (Fujimura).
Melting point: mp 160°
Toxicity data: LD50 in mice (mg/kg): 790 i.p., 2800 orally (Fujimura)
NOTE: Component in combination analgesics containing ethenzamide, caffeine and vitamin B1, e.g. Butylon (Grelan) , Bucetalon (Isei) .
Therap-Cat: Analgesic.
Keywords: Analgesic (Non-Narcotic).