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CAS No 106362-32-7 , L-Threonine,L-alanyl-L-seryl-L-threonyl-L-threonyl-L-threonyl-L-asparaginyl-L-tyrosyl-

  • Name: L-Threonine,L-alanyl-L-seryl-L-threonyl-L-threonyl-L-threonyl-L-asparaginyl-L-tyrosyl-
  • Synonyms: 1230: PN: US20090175821 SEQID: 1506 claimed protein; 5: PN: EP1479689 SEQID: 5 claimed sequence; 1: PN: WO2006138745 PAGE: 8 unclaimedsequence; 1:PN: WO03050136 SEQID: 1 claimed sequence; 224: PN: WO0069900SEQID: 1523 unclaimed sequence;L-Threonine,L-alanyl-L-seryl-L-threonyl-L-threonyl-L-threonyl-L-asparaginyl-L-tyrosyl-; 2: PN: US20030049253 PAGE: 17 claimed sequence; 208: PN: WO0069900SEQID: 1507 unclaimed sequence; 17: PN: US20060223140SEQID: 16 claimed protein; 1: PN: US20050176079 SEQID: 1 claimed sequence;L-Threonine,N-[N-[N2-[N-[N-[N-(N-L-alanyl-L-seryl)-L-threonyl]-L-threonyl]-L-threonyl]-L-asparaginyl]-L-tyrosyl]-; 207: PN: WO0069900 SEQID: 1506 unclaimed sequence; 215: PN: WO2008058016 SEQID: 219 claimedprotein; Peptide T; 223: PN: WO0069900 SEQID: 1522 unclaimed sequence; 3: PN: US6011014 SEQID: 5claimed protein;2: PN: WO2007117596 SEQID: 22 unclaimed sequence;
  • CAS Registry Number:
  • Flash Point: 860.7°C
  • Boiling Point: 1499.5°Cat760mmHg
  • Density: 1.432g/cm3
  • Refractive index: 1.596
  • Flash Point: 860.7°C
  • Molecular Weight: 0
  • InChI: InChI=1/C35H55N9O16/c1-13(36)28(52)40-22(12-45)31(55)41-25(15(3)47)33(57)43-26(16(4)48)34(58)42-24(14(2)46)32(56)39-21(11-23(37)51)29(53)38-20(10-18-6-8-19(50)9-7-18)30(54)44-27(17(5)49)35(59)60/h6-9,13-17,20-22,24-27,45-50H,10-12,36H2,1-5H3,(H2,37,51)(H,38,53)(H,39,56)(H,40,52)(H,41,55)(H,42,58)(H,43,57)(H,44,54)(H,59,60)/t13-,14+,15+,16+,17+,20-,21-,22-,24-,25-,26-,27-/m0/s1
  • Molecular Formula: C35H55 N9 O16
  • Molecular Structure:CAS No:106362-32-7 L-Threonine,L-alanyl-L-seryl-L-threonyl-L-threonyl-L-threonyl-L-asparaginyl-L-tyrosyl-

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References of L-Threonine,L-alanyl-L-seryl-L-threonyl-L-threonyl-L-threonyl-L-asparaginyl-L-tyrosyl-
Title: Peptide T
CAS Registry Number: 106362-32-7
Molecular Formula: C35H55N9O16
Molecular Weight: 857.86
Percent Composition: C 49.00%, H 6.46%, N 14.69%, O 29.84%
Literature References: Octapeptide segment of the human immunodeficiency virus (HIV) envelope glycoprotein (gp 120); named peptide T because of its high threonine content. Has been reported to block the in vitro binding of HIV envelope to human leukocyte receptor CD4. Isolation, neuropharmacology and anti-HIV activity of peptide and analogs: C. B. Pert et al., Proc. Natl. Acad. Sci. USA 83, 9254 (1986). Characterization of active core structure, T[4-8], and chemotactic effects: C. B. Pert, M. R. Ruff, Clin. Neuropharmacol. 9, Suppl. 4, 482 (1986). Chemotactic effects and structural homology with vasoactive intestinal peptide (VIP), q.v.: M. R. Ruff et al., FEBS Lett. 211, 17 (1987). Competitive binding studies at VIP receptor: T. D. Nguyen, Peptides 9, 425 (1988). Structural homology with thymosin a1, q.v.: T. D. Nguyen, L. A. Scheving, Biochem. Biophys. Res. Commun. 145, 884 (1987). Evaluation of anti-HIV activity: J. Sodroski et al., Lancet 1, 1428 (1987). Clinical evaluation in treatment of AIDS: L. Wetterberg et al., ibid. 159. Chromatographic purification of [D-ala1] peptide T amide, a metabolically stable and more potent analog of peptide T: T. R. Burke, M. Knight, J. Chromatogr. 411, 431 (1987). Blood to brain transport of the amide in mice: C. M. Barrera et al., Brain Res. Bull. 19, 629 (1987). Brief review of debate over effectiveness of peptide T: D. M. Barnes, Science 237, 128 (1987).