Home > Name List By 4 > 4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1- one

CAS No 10457-90-6 , 4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-
one

  • Name: 4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-
    one
  • Synonyms: BRN 1552256; Bromoperidol; EINECS 233-943-3; CC 2489; Bromperidolum [INN-Latin]; 10457-90-6;Impromen; R 11333;4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-
    one;
  • CAS Registry Number:
  • Density: 1.366 g/cm3
  • Refractive index: 1.59
  • Hazard Symbols: Xn
  • EINECS: 233-943-3
  • Molecular Weight: 420.315223
  • InchiKey: RKLNONIVDFXQRX-UHFFFAOYSA-N
  • InChI: InChI=1S/C21H23BrFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-
    2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
  • Risk Statements: 22
  • Molecular Formula: C21H23BrFNO2
  • Molecular Structure:CAS No:10457-90-6 4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-<br />one
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10457-90-6 BROMPERIDOL

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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10457-90-6 Bromoperidol

  • United States Waterstone Technology LLC [Manufacturer]
  • Tel: 317-644-0862/ 317-218-7464
  • Fax: 317-569-8068
  • Address: Waterstone Technology LLC
    12202 Hancock Street
    Carmel, IN. 46032 ,United States
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10457-90-6 Bromperidol

  • Bromperidol
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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10457-90-6 Bromperidol

  • Bromperidol, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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10457-90-6 Bromperidol

  • China Haihang Industry Co., Ltd. []
  • Tel: +86-(531)-88032799
  • Fax: +86-(531)-85821093
  • Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100, ,China
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10457-90-6 Bromperidol

  • India Manus Aktteva []
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, ,India
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10457-90-6 Bromperidol

  • Bromperidol, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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10457-90-6 Bromperidol

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10457-90-6 Bromperidol

  • India JAI RADHE SALES []
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. ,India
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10457-90-6 Bromperidol

  • India Shreeji Pharma International [Manufacturers]
  • Tel: +91-265-3019110
  • Fax: +91-265-2465036
  • Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018, Vadodara,GujaratIndia
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References of 4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-
one
Title: Bromperidol
CAS Registry Number: 10457-90-6
CAS Name: 4-[4-(4-Bromophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone
Synonyms: 4-[4-(p-bromophenyl)-4-hydroxypiperidino]-4¢-fluorobutyrophenone
Manufacturers' Codes: R-11333
Trademarks: Azurene (Cilag-Chemie); Impromen (Janssen); Tesoprel (Organon)
Molecular Formula: C21H23BrFNO2
Molecular Weight: 420.32
Percent Composition: C 60.01%, H 5.52%, Br 19.01%, F 4.52%, N 3.33%, O 7.61%
Literature References: Bromine analog of haloperidol, q.v. Prepn (no data): P. A. J. Janssen, GB 895309; idem, US 3438991 (1962, 1969 both to Janssen); C. J. E. Niemegeers, P. A. J. Janssen, Arzneim.-Forsch. 24, 45 (1974). Prepn of 82Br bromperidol and preliminary tissue distribution studies: S. H. Vincent et al., J. Med. Chem. 23, 75 (1980). Pharmacological study: C. J. E. Niemegeers, P. A. J. Janssen, Life Sci. 24, 2201 (1979). Preliminary clinical study: B. Woggon et al., Int. Pharmacopsychiatry 14, 213 (1979). Radioimmunoassay: E. Van Den Eeckhout et al., Eur. J. Drug Metab. Pharmacokinet. 5, 45 (1980).
Properties: Off-white amorphous or microcrystalline powder, mp 155-158°. uv max: 245 nm. pKa 8.6-8.7. Soly in water: 0.09 mg/ml; in 0.1M tartaric, lactic, citric and acetic acids: greater than or equal to 10 mg/ml.
Melting point: mp 155-158°
pKa: pKa 8.6-8.7
Absorption maximum: uv max: 245 nm
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Butyrophenones.