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CAS No 104-06-3 , N-[4-[(E)-(carbamothioylhydrazinylidene)methyl]phenyl]acetamide

  • Name: N-[4-[(E)-(carbamothioylhydrazinylidene)methyl]phenyl]acetamide
  • Synonyms: Tubin; Conteben; Benzothiozane;AMITHIOZONE;N-[4-[(E)-(carbamothioylhydrazinylidene)methyl]phenyl]acetamide; Ambathizon; Thioacetazon; Tibon; Parazone; Thiacetazone;
  • CAS Registry Number:
  • Melting Point: 225-230 °C
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.3g/cm3
  • Refractive index: 1.639
  • Safety Statements: Moderately toxic by ingestion and subcutaneous routes. Mutation data reported. A tuberculostatic antibacterial agent. When heated to decomposition it emits very toxic fumes of NOx and SOx.
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: °C
  • EINECS: 203-170-6
  • Molecular Weight: 236.29348
  • InchiKey: SRVJKTDHMYAMHA-WUXMJOGZSA-N
  • InChI: InChI=1S/C10H12N4OS/c1-7(15)13-9-4-2-8(3-5-9)6-12-14-10(11)16/h2-6H,1H3,
    (H,13,15)(H3,11,14,16)/b12-6+
  • Risk Statements: 22
  • Molecular Formula: C10H12N4OS
  • Molecular Structure:CAS No:104-06-3 N-[4-[(E)-(carbamothioylhydrazinylidene)methyl]phenyl]acetamide
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104-06-3 4-Acetylaminobenzaldehyde thiosemicarbazone; 98%

  • 4-Acetylaminobenzaldehyde thiosemicarbazone; 98%
  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
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  • Address: Im Schlehert 10
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    Germany null,nullGermany
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104-06-3 4-ACETYLAMINOBENZALDEHYDE THIOSEMICARBAZONE

  • 4-ACETYLAMINOBENZALDEHYDE THIOSEMICARBAZONE
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
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    Hong Kong null,nullHong kong
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104-06-3 Acetylaminobenzaldehyde thiosemicarbazone, 4-

  • Acetylaminobenzaldehyde thiosemicarbazone, 4-
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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104-06-3 4-Acetylaminobenzaldehyde thiosemicarbazone

  • 4-Acetylaminobenzaldehyde thiosemicarbazone
  • Switzerland CONNECT MARKETING GMBH [Manufacturer]
  • Tel: +41 81 740 58 50
  • Fax: +41 81 740 58 51
  • Address: CONNECT MARKETING GMBH
    BAHNWEG NORD 35
    CH-9475 SEVELEN/SG
    SWITZERLAND null,nullSwitzerland
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104-06-3 4-Acetylaminobenzaldehyde thiosemicarbazone

  • 4-Acetylaminobenzaldehyde thiosemicarbazone, 98%
  • Slovakia Georganics Ltd. [Manufacturer]
  • Tel: +421 33 6403132
  • Fax: +421 33 6403133
  • Address: Georganics Ltd
    Korenicova 1
    811 03 Bratislava
    Slovak Republic null,nullSlovakia
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104-06-3 ACETYLAMINOBENZALDEHYDE THIOSEMICARBAZONE

  • France GTH Chimie Fine - Fine Chemicals [Manufacturer]
  • Tel: +33 3 44 21 60 30/ +33 6 07 47 90 01 (mobile)
  • Fax: + 33 3 44 21 60 31
  • Address: 72, avenue Charles de Gaulle
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104-06-3 Thiacetazone

  • Thiacetazone
  • Germany Intatrade Chemicals null
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  • Address: Vierzoner Strasse 14 D-06749 Bitterfeld, Germany null,nullGermany
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104-06-3 Thiacetazone

  • India Exim-Pharm International null
  • Tel: +91-(22)-26191948
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  • Address: 1, Ashish Mahal, 2nd Floor, Ist Road, Golibar Santacruz (E), Mumbai, Maharashtra 400 055, null,nullIndia
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104-06-3 Thiacetazone, BP

  • Thiacetazone, BP
  • India G. Amphray Laboratories [Manufacturer]
  • Tel: +91 (22) 22 66 10 34
  • Fax: +91 (22) 22 82 81 81
  • Address: Sambava Chambers, 4th Floor, Sir P.M.Road, Fort, Mumbai - 400 001, INDIA.400 001 MumbaiINDIA 400 001 Mumbai,nullIndia
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104-06-3 4-ACETYLAMINOBENZALDEHYDE THIOSEMICARBAZONE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of N-[4-[(E)-(carbamothioylhydrazinylidene)methyl]phenyl]acetamide
Title: Thiacetazone
CAS Registry Number: 104-06-3
CAS Name: N-[4-[[(Aminothioxomethyl)hydrazono]methyl]phenyl]acetamide
Synonyms: 2-[[4-(acetylamino)phenyl]methylene]hydrazinecarbothioamide; 4¢-formylacetanilide thiosemicarbazone; p-acetamidobenzaldehyde thiosemicarbazone; p-acetylaminobenzaldehyde thiosemicarbazone; p-acetaminobenzylidenethiosemicarbazone; amithiozone; thibone; thioacetazone
Manufacturers' Codes: Tb I-698
Trademarks: Conteben (Bayer); Livazone (Specia); Myrizone (Squibb); Neustab (Boots); Panrone (Panray); Seroden (Allen & Hanburys); Tebethion; Thiocarbazil; Thioparamizone (Smith & Nephew); Tibione (Schenley); Tiobicina
Molecular Formula: C10H12N4OS
Molecular Weight: 236.29
Percent Composition: C 50.83%, H 5.12%, N 23.71%, O 6.77%, S 13.57%
Literature References: Prepn: G. Domagk et al., Naturwissenschaften 33, 315 (1946); Behnisch et al., Angew. Chem. 60A, 113 (1948); Chabrier, Cattelain, Bull. Soc. Chim. Fr. 1950M, 52; Das, Mukherjee, J. Am. Chem. Soc. 75, 1241 (1953). Toxicity data: Bavin et al., J. Pharm. Pharmacol. 2, 764 (1950). HPLC determn in body fluids: P. J. Jenner, J. Chromatogr. 276, 463 (1983). Review of clinical experience: H. C. Hinshaw, W. McDermott, Am. Rev. Tuberc. 61, 145-157 (1950); of clinical safety and efficacy: P. Nunn et al., Trans. R. Soc. Trop. Med. Hyg. 87, 578 (1993).
Properties: Minute, pale yellow crystals from abs alc. Bitter taste. Darkens on exposure to light. Dec 225-230°. uv max (ethanol): 328 nm, extinction 0.580. Sol in hot alc; very sparingly sol in cold alc. Insol in water, acetone, benzene, carbon tetrachloride, chloroform, carbon disulfide, petr ether. Practically insol in the other common organic solvents except glycols. Soly in propylene glycol ~1%. LD50 s.c. in mice: 1-2 g/kg (Bavin).
Absorption maximum: uv max (ethanol): 328 nm
Toxicity data: LD50 s.c. in mice: 1-2 g/kg (Bavin)
Therap-Cat: Antibacterial (tuberculostatic).
Keywords: Antibacterial (Tuberculostatic).