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CAS No 10318-26-0 , Galactitol,1,6-dibromo-1,6-dideoxy-

  • Name: Galactitol,1,6-dibromo-1,6-dideoxy-
  • Synonyms: DBD; DBD (alcohol); Elobromol; Dibromdulcit; NSC 104800; 1,6-Dibromodideoxydulcitol;Galactitol,1,6-dibromo-1,6-dideoxy-;1,6-Dibromodulcitol;Dibromogalactitol; Dibromodulcitol; NCI C04795; Mitolactol;1,6-Dibromo-1,6-dideoxy-D-dulcitol;1,6-Dibromo-1,6-dideoxydulcitol;
  • CAS Registry Number:
  • Melting Point: 183-185
  • Flash Point: 263°C
  • Boiling Point: 511.2°Cat760mmHg
  • Density: 2.117g/cm3
  • Refractive index: 1.622
  • Water Solubility: Insoluble (
  • Safety Statements: Poison by ingestion. Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Human mutation data reported. An anti-cancer agent taken orally. When heated to decomposition it emits very toxic fumes of Br−.
  • Flash Point: 263°C
  • EINECS: 207-676-8
  • Molecular Weight: 308.00
  • InChI: InChI=1/C6H12Br2O4/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,9-12H,1-2H2/t3-,4+,5+,6-
  • Molecular Formula: C6H12 Br2 O4
  • Molecular Structure:CAS No:10318-26-0 Galactitol,1,6-dibromo-1,6-dideoxy-

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References of Galactitol,1,6-dibromo-1,6-dideoxy-
Title: Mitolactol
CAS Registry Number: 10318-26-0
CAS Name: 1,6-Dibromo-1,6-dideoxygalactitol
Synonyms: 1,6-dibromo-1,6-dideoxydulcitol; dibromodulcitol; dibromodulcit; DBD
Manufacturers' Codes: NSC-104800
Trademarks: Elobromol (Chinoin)
Molecular Formula: C6H12Br2O4
Molecular Weight: 307.97
Percent Composition: C 23.40%, H 3.93%, Br 51.89%, O 20.78%
Literature References: Diastereoisomer of mitobronitol, q.v., with myelosuppressive effects. Prepn and anticancer activity: NL 6600395; P. Horváth-Lengyel et al., US 3993781 (1966, 1976 both to Chinoin); B. Kellner et al., Nature 213, 402 (1967). Structure-activity correlations: L. Institoris et al., Arzneim.-Forsch. 17, 145 (1967). Pharmacological study: T. H. Corbett et al., Cancer 40, Suppl. 5, 2660 (1977). Metabolism, pharmacokinetics: I. P. Horváth et al., Eur. J. Cancer 15, 337 (1979). Clinical studies: W. Medina, J. M. Kirkwood, Cancer Treat. Rep. 66, 195 (1982); D. C. Tormey et al., Am. J. Clin. Oncol. 5, 33 (1982).
Properties: Crystals from methanol, aq alc, or aq acetone, mp 187-188° (dec). LD50 in rats (mg/kg): 1400 orally; 470 i.p. (Kellner).
Melting point: mp 187-188° (dec)
Toxicity data: LD50 in rats (mg/kg): 1400 orally; 470 i.p. (Kellner)
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Alkylating Agents.