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CAS No 100-92-5 , N,2-dimethyl-1-phenylpropan-2-amine

  • Name: N,2-dimethyl-1-phenylpropan-2-amine
  • Synonyms: Wyfentermina; Vialin; Mefenterdrin; Mephenterdrinum; Wyamine; Mephine; Mefentermin; Mephetedrine;Mephenterdrine;N,2-dimethyl-1-phenylpropan-2-amine;
  • CAS Registry Number:
  • Flash Point: 90°C
  • Boiling Point: 229.4°Cat760mmHg
  • Density: 0.903g/cm3
  • Refractive index: 1.501
  • Flash Point: 90°C
  • EINECS: 202-901-6
  • Molecular Weight: 163.25938
  • InchiKey: RXQCGGRTAILOIN-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H17N/c1-11(2,12-3)9-10-7-5-4-6-8-10/h4-8,12H,9H2,1-3H3
  • Molecular Formula: C11H17N
  • Molecular Structure:CAS No:100-92-5 N,2-dimethyl-1-phenylpropan-2-amine

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100-92-5 Mephentermine

  • IUPAC NAME-N,2-dimethyl-1-phenylpropan-2-amine MOLECULAR FORMULA-C11H17N MOLAR MASS-163.259 g/mol
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100-92-5 Mephentermine Base

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100-92-5 Mephentermine

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100-92-5 Benzeneethanamine, N,a,a-trimethyl-

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100-92-5 MEPHENTERMINE

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1/1
References of N,2-dimethyl-1-phenylpropan-2-amine
Title: Mephentermine
CAS Registry Number: 100-92-5
CAS Name: N,a,a-Trimethylbenzeneethanamine
Synonyms: 2-methylamino-2-methyl-1-phenylpropane; N-methyl-w-phenyl-tert-butylamine; N,a,a-trimethylphenethylamine
Molecular Formula: C11H17N
Molecular Weight: 163.26
Percent Composition: C 80.92%, H 10.50%, N 8.58%
Literature References: a-Adrenergic agonist. Prepd by hydrogenating 1-chloro-2-methylamino-2-methyl-1-phenylpropane hydrochloride in methanol in the presence of palladium barium carbonate: Bruce, Szabo, US 2597445 (1952 to Wyeth). Alternate process: Abel et al., US 2590079 (1952 to Wyeth). Pharmacology: D. K. Eckfeld et al., J. Am. Pharm. Assoc. 43, 705 (1954).
Properties: Liquid. Fishy amine odor. bp7mm 82-83°. n20D 1.5110. d2020 0.9231. pKa (30°) 10.35. Alkaline reaction. Freely sol in alc. Sol in ether. Practically insol in water.
Boiling point: bp7mm 82-83°
pKa: pKa (30°) 10.35
Index of refraction: n20D 1.5110
Density: d2020 0.9231
 
Derivative Type: Sulfate dihydrate
CAS Registry Number: 6190-60-9
Trademarks: Wyamine (Wyeth); Mephine
Molecular Formula: (C11H17N)2.H2SO4.2H2O
Molecular Weight: 460.63
Percent Composition: C 57.36%, H 8.75%, N 6.08%, S 6.96%, O 20.84%
Properties: Crystals, mp 215-217° (dec). One gram dissolves in 20 ml water, about 150 ml ethanol (95%). Practically insol in chloroform. pH of aq soln about 6. LD50 (calc as base) intra-abdominally in mice: 89.4 mg/kg (Eckfeld).
Melting point: mp 215-217° (dec)
Toxicity data: LD50 (calc as base) intra-abdominally in mice: 89.4 mg/kg (Eckfeld)
 
Therap-Cat: Antihypotensive.
Keywords: a-Adrenergic Agonist.