Home > Pharmaceuticals and Biochemicals > Antineoplastic Agents : 4345 Products found
Substances that inhibit or prevent the proliferation of NEOPLASMS.
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    • VX-680(Tozasertib) 639089-54-6

    • VX-680 (Tozasertib, MK-0457) is a pan-Aurora inhibitor, mostly against Aurora A with Kiapp of 0.6 nM, less potent towards Aurora B/Aurora C and 100-fold more selective for Aurora A than 55 other kinases. Phase 2.
    • FOB Price: USD150 - 960 / null
    • China Wuhan Sun-shine chemical Corporation Limited [Manufacturer, Trading Company]
    • Tel: 86--18312560332
    • Fax: --
    • Address: No.8 Rd, the Great Wall Park, DonghuHigh-Tech District wuhan,HubeiChina
    Contact Supplier

    AZ3146 1124329-14-1

    • AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit.
    • FOB Price: USD200 - 1320 / null
    • China Wuhan Sun-shine chemical Corporation Limited [Manufacturer, Trading Company]
    • Tel: 86--18312560332
    • Fax: --
    • Address: No.8 Rd, the Great Wall Park, DonghuHigh-Tech District wuhan,HubeiChina
    Contact Supplier

    XL-880,Foretinib 849217-64-7

    • Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50of 0.4 nM and 0.9 nM. Less potent against Ron, Flt-1/3/4, Kit, PDGFR/ and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
    • FOB Price: USD150 - 960 / null
    • China Wuhan Sun-shine chemical Corporation Limited [Manufacturer, Trading Company]
    • Tel: 86--18312560332
    • Fax: --
    • Address: No.8 Rd, the Great Wall Park, DonghuHigh-Tech District wuhan,HubeiChina
    Contact Supplier

    Vigabatrin 60643-86-9

    • Vigabatrin, also known as gamma-vinyl-GABA, is an antiepileptic drug that inhibits the breakdown of -aminobutyric acid (GABA) by acting as a suicide inhibitor of GABA transaminase (GABA-T). It is a structural analog of GABA, but does not bind to GABA...
    • FOB Price: USD150 - 1000 / null
    • China Wuhan Sun-shine chemical Corporation Limited [Manufacturer, Trading Company]
    • Tel: 86--18312560332
    • Fax: --
    • Address: No.8 Rd, the Great Wall Park, DonghuHigh-Tech District wuhan,HubeiChina
    Contact Supplier

    AT13148 1056901-62-2

    • AT13148, a first-in-class multi-AGC kinase inhibitor, against gastric cancer cells. AT13148 exerted potent cytotoxic and anti-proliferative activities against a panel human gastric cancer cell lines (HGC-27, AGS, SNU-601, N87 and MKN-28), possibly vi...
    • FOB Price: USD300 - 2000 / null
    • China Wuhan Sun-shine chemical Corporation Limited [Manufacturer, Trading Company]
    • Tel: 86--18312560332
    • Fax: --
    • Address: No.8 Rd, the Great Wall Park, DonghuHigh-Tech District wuhan,HubeiChina
    Contact Supplier

    Carfilzomib(PR-171) 868540-17-4

    • Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM.
    • FOB Price: USD250 - 1000 / null
    • China Wuhan Sun-shine chemical Corporation Limited [Manufacturer, Trading Company]
    • Tel: 86--18312560332
    • Fax: --
    • Address: No.8 Rd, the Great Wall Park, DonghuHigh-Tech District wuhan,HubeiChina
    Contact Supplier

    SNS-032(BMS-387032) 345627-80-7

    • SNS-032 has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6. Phase 1.
    • FOB Price: USD250 - 1340 / null
    • China Wuhan Sun-shine chemical Corporation Limited [Manufacturer, Trading Company]
    • Tel: 86--18312560332
    • Fax: --
    • Address: No.8 Rd, the Great Wall Park, DonghuHigh-Tech District wuhan,HubeiChina
    Contact Supplier

    Rucaparib(AG-014699,PF-01367338) 459868-92-9

    • Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1, also showing binding affinity to eight other PARP domains. Phase 3.
    • FOB Price: USD300 - 1840 / null
    • China Wuhan Sun-shine chemical Corporation Limited [Manufacturer, Trading Company]
    • Tel: 86--18312560332
    • Fax: --
    • Address: No.8 Rd, the Great Wall Park, DonghuHigh-Tech District wuhan,HubeiChina
    Contact Supplier

    Tildipirosin 328898-40-4

    • Tildipirosin (TIP) is a novel 16-membered-ring macrolide authorized for the treatment of bovine and swine respiratory disease. Tildipirosin is developed to treat bacterial pathogens, including Mannheimia haemolytica and Pasteurella multocida, that ca...
    • FOB Price: USD250 - 1200 / null
    • China Wuhan Sun-shine chemical Corporation Limited [Manufacturer, Trading Company]
    • Tel: 86--18312560332
    • Fax: --
    • Address: No.8 Rd, the Great Wall Park, DonghuHigh-Tech District wuhan,HubeiChina
    Contact Supplier

    KRN 633 286370-15-8

    • KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM, weakly inhibits PDGFR-/ and c-Kit, does not block the phosphorylation of FGFR-1, EGFR or c-Met in cell.
    • FOB Price: USD200 - 1300 / null
    • China Wuhan Sun-shine chemical Corporation Limited [Manufacturer, Trading Company]
    • Tel: 86--18312560332
    • Fax: --
    • Address: No.8 Rd, the Great Wall Park, DonghuHigh-Tech District wuhan,HubeiChina
    Contact Supplier
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