Irinotecan

CAS No.: 97682-44-5
Purity: 98.0%
Min quantity: 10 Kilograms
Weight: 586.67802
Place of Orign: Shirley,New York,United States

Contact:Ms.Alex Brown

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BOC Sciences
United States
Contact:Ms.Alex Brown
Tel:1-631-4854226
Total Annual Sales Volume:US$5 Million - US$10 Million
Number of Employees:101 - 500 People
Business Type:Manufacturer
Main Markets:North America,Southeast Asia,Mid East,South America,Africa,Eastern Asia,Eastern Europe,Oceania,Western Europe

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Item specifics

Product Name.:Irinotecan
CAS No: 97682-44-5
Weight: 586.67802
Formula: C₃₃H₃₈N₄O₆
Melting Point: 222-223 deg C
Boiling Point: 873.4 °C at 760 mmHg
Density: 1.4 g/cm³

Details

Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively. It is used for the treatment of colon and rectum cancers. It binds to topoisomerase I-DNA complex, preventing religation of the DNA strand and leading to double-strand DNA breakage and cell death.https://www.bocsci.com/irinotecan-cas-97682-44-5-item-84-101283.html

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